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T9235GW604714XInhibitor,mitochondrial respiration,Mitochondrial Metabolism,Parkinson’s Disease,MCT1,GW604
GW604714X were found to be potent inhibitors of mitochondrial respiration supported by pyruvate
价 格:¥电议型 号:T9235产 地:中国大陆
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T6347Ki16198lung,Ki 16198,inhibit,Inhibitor,LPL Receptor,BxPC-3,liver metastasis,Ki16198,Ki-16198,Lysopho
Ki16198 is the methyl ester of Ki16425, which is a LPA antagonist and inhibits LPA1- and LPA3-induced inositol phosphate production with Ki of 0.34 μM and 0.93 μM, respectively, shows weaker inhibition for LPA2, no activity at LPA4, LPA5, LPA6.
价 格:¥电议型 号:T6347产 地:中国大陆
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T8471VonafexorNR1H4,HBV,FXR,EYP 001,Inhibitor,Vonafexor,EYP-001,inhibit,Hepatitis B virus
Vonafexor is a farnesoid X receptor (FXR, NR1H4) agonist, with anti-HBV effects
价 格:¥电议型 号:T8471产 地:中国大陆
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T41275PF-04753299PF04753299,PF 04753299
PF-04753299 is a potent and selective inhibitor of UDP-3-O-(R-3-hydroxymyristol)-N-acetylglucosamine deacetylase (LpxC). PF-04753299 is bactericidal for the gonococcal isolates. PF-04753299 inhibits E. coli, P. aeruginosa and K. pneumoniae strains with MIC 90 values of 2 μg/ml, 4 μg/ml and 16 μg/ml, respectively. PF-04753299 is used for the study of gram-negative bacteria infection [1].
价 格:¥电议型 号:T41275产 地:中国大陆
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T8247(+)-Aromadendrene(+)Aromadendrene,(+) Aromadendrene
(+)-Aromadendrene is a natural product that has significant antibacterial activity against the Gram-positive and Gram-negative bacteria.
价 格:¥电议型 号:T8247产 地:中国大陆
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T6947PiperlongumineExtracellular signal regulated kinases,Ferroptosis,Bacterial,Inhibitor,inhibit,Apoptos
Piperlongumine is a natural alkaloid from Piper longum L. It selectively kills cancer cells and strengthens the level of reactive oxygen species (ROS).
价 格:¥电议型 号:T6947产 地:中国大陆
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T60122AldometanibCompoundIA47
Aldometanib (LXY-05-029) is an orally active aldolase inhibitor. Aldometanib prevents FBP from binding to v-ATPase-associated aldolase and activates lysosomal AMPK. Aldometanib can be used for the research of metabolic homeostasis [1].
价 格:¥电议型 号:T60122产 地:中国大陆
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T7309TAS-103 dihydrochlorideBMS247615,Topoisomerase,TAS-103,TAS103,inhibit,TAS 103 dihydrochloride,BMS-24
TAS-103 (dihydrochloride) is a novel anticancer agent targeting both topoisomerase (Topo) I and Topo II.
价 格:¥电议型 号:T7309产 地:中国大陆
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T7947FT113FT 113,Fatty Acid Synthase (FASN),Inhibitor,FT-113,FT113,inhibit
FT113 is a novel potent inhibitor of fatty acid synthase (fasn, IC50 : 213 nM),and exhibits anti-cancer activity
价 格:¥电议型 号:T7947产 地:中国大陆
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T7152Ravuconazoleinhibit,ER30346,BMS207147,Ravuconazole,BMS 207147,Fungal,ER 30346,Inhibitor
Ravuconazole is a potent triazole antifungal that potently inhibits a wide range of fungi.
价 格:¥电议型 号:T7152产 地:中国大陆
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T64337PF-04745637PF04745637,Inhibitor,bowel,TRPA1,disease,inhibit,respiratory,PF-04745637,Transient recept
PF-04745637 is a potent and selective TRPA1 antagonist with an IC50 of 17 nM[1].
价 格:¥电议型 号:T64337产 地:中国大陆
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TP1875LCDK2 acetate(255064-79-0 free base)CDK2 acetate(255064790 free base),CDK-2 acetate(255064-79-0 free
CDK2 acetate is a member of the eukaryotic S/T protein kinase family and its function is to catalyze the phosphoryl transfer of ATP γ-phosphate to serine or threonine hydroxyl (denoted as S0/T0) in a protein substrate.
价 格:¥电议型 号:TP1875L产 地:中国大陆
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T6479Dovitinib lactate hydrateVEGFR1,FGFR1,TKI258 lactate,SCFR,CD117,Dovitinib lactate hydrate,FGFR,Fms l
Dovitinib (TKI258) Lactate is the Lactate of Dovitinib, which is a multitargeted RTK inhibitor, mostly for class III (FLT3/c-Kit) with IC50 of 1 nM/2 nM, also potent to class IV (FGFR1/3) and class V (VEGFR1-4) RTKs with IC50 of 8-13 nM, less potent to InsR, EGFR, c-Met, EphA2, Tie2, IGFR1 and HER2. Phase 4.
价 格:¥电议型 号:T6479产 地:中国大陆
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T6473DioscinAutophagy,CCRIS-4123,CCRIS4123,Apoptosis,Dioscin,inhibit,Inhibitor
Dioscin is a saponin with antitumor activities.
价 格:¥电议型 号:T6473产 地:中国大陆
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T8875CD73-IN-3Inhibitor,cancer,CD73 IN 3,CD-73-IN-3,CD73IN3,CD73,Immunosuppression,tumor,inhibit
LY-3475070 is a potent and selective CD73 inhibitor with an IC50 of 28 nM, and its use alone or in combination with pembrolizumab is currently being tested in patients with advanced cancer.
价 格:¥电议型 号:T8875产 地:中国大陆
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TN1471Cassiaside Cnephropathy,Diabetic,mesangial cell,end products,Endogenous Metabolite,Cassiae Semen,TGF
Cassiaside C is a naphthopyrone isolated from the seed of Cassia tora. It has inhibitory activity on advanced glycation end products (AGE) formation in vitro.
价 格:¥电议型 号:TN1471产 地:中国大陆
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TP1666LKisspeptin-10, rat acetate(478507-53-8 free base)Kisspeptin10, rat acetate(478507538 free base),Kiss
Endogenous ligand for the rodent kisspeptin receptor (KISS1, GPR54).
价 格:¥电议型 号:TP1666L产 地:中国大陆
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T9347EAAT2 activator 1GLT-1,Excitatory amino acid transporter 2,inhibit,Glutamate transporter 1,Inhibitor
F2005-0304 is a thiopyridazine derivative that has been found to increase EAAT2 protein levels in astrocytes.
价 格:¥电议型 号:T9347产 地:中国大陆