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T7558CID-1067700ML282,competitively,CID1067700,brain,Rab7,ML 282,GTPase,Ras,machinery,Ras-related,CID-106
CID-1067700 is one of the first identified competitive inhibitors of nucleotide binding by Ras-related GTPases(Rab7 with a Ki of 13 nM).
价 格:¥电议型 号:T7558产 地:中国大陆
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T22552LAD57AD57
AD57 is a potent inhibitor of both c-Src and Abl with IC50 of 0.025 μM and 0.041 μM, respectively.
价 格:¥电议型 号:T22552L产 地:中国大陆
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T8230PNU112455A hydrochlorideanticooperative,Cyclin dependent kinase,PNU112455A hydrochloride,Alzheimer’s
PNU 112455A is an ATP site competetive inhibitor of CDK2 and CDK5,binds to the ATP site of CDK2 and CDK5 with Kms of 3.6 and 3.2 μM, respectively.
价 格:¥电议型 号:T8230产 地:中国大陆
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T9011VU0155094VU0155094,Inhibitor,Metabotropic glutamate receptors,ML397,inhibit,mGluR
ML397 is a positive allosteric modulator with differential activity at the various group III mGluRs.
价 格:¥电议型 号:T9011产 地:中国大陆
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T10855CO23CO23,CO-23
CO23 is a blood-brain barrier penetrant and selective TRα agonist and can be used in studies about the regulation of growth and development.
价 格:¥电议型 号:T10855产 地:中国大陆
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TP1875LCDK2 acetate(255064-79-0 free base)CDK2 acetate(255064790 free base),CDK-2 acetate(255064-79-0 free
CDK2 acetate is a member of the eukaryotic S/T protein kinase family and its function is to catalyze the phosphoryl transfer of ATP γ-phosphate to serine or threonine hydroxyl (denoted as S0/T0) in a protein substrate.
价 格:¥电议型 号:TP1875L产 地:中国大陆
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T6602Naratriptan hydrochlorideNaratriptan hydrochloride,Inhibitor,GR-85548A,Naratriptan,5-HT Receptor,5-h
Naratriptan Hydrochloride is the hydrochloride salt form of naratriptan, a sulfonamide with selective serotonin (5-HT) 1 receptor agonistic activity and anti-migraine property. Naratriptan hydrochloride binds selectively and with high affinity to the 5-HT1D and 5-HT1B receptor subtypes. Activation of these 5-HT1D/B receptors located on intracranial blood vessels leads to vasoconstriction and provides relief of migraine headaches. Naratriptan hydrochloride may also exerts its effect by stimulatio
价 格:¥电议型 号:T6602产 地:中国大陆
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T17255WJ460WJ-460,WJ460
WJ460 is an effective inhibitor of myoferlin. WJ460 exerts anti-metastatic activity in breast cancer cells.
价 格:¥电议型 号:T17255产 地:中国大陆
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T0155ArgatrobanArgatroban,MCI 9038,MCI9038,MD805,inhibit,MD 805,Inhibitor,Thrombin
Argatroban, a specific thrombin inhibitor, which is a non-heparin anticoagulant, prevents the formation of thrombi.
价 格:¥电议型 号:T0155产 地:中国大陆
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T12424PF-06305591
PF-06305591 is an effective and selective blocker of voltage-gated sodium channel NaV1.8 (IC50 = 15 nM).
价 格:¥电议型 号:T12424产 地:中国大陆
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T7382NBD-557HIV,NBD557,NBD 557,NBD-557,inhibit,Human immunodeficiency virus,Inhibitor
NBD-557 is a potentially HIV-1 inhibitor.
价 格:¥电议型 号:T7382产 地:中国大陆
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T40555LLyP-1 acetateLyP 1 acetate,LyP1 acetate
LyP-1 acetate is a tumor homing peptide specifically binding to p32 receptors overexpressed in various tumor-associated cells.
价 格:¥电议型 号:T40555L产 地:中国大陆
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TQ0255OlafertinibInhibitor,ErbB-1,Olafertinib,Epidermal growth factor receptor,NSCLC,HER1,EGFR,inhibit
CK-101 (RX-518) is a novel mutant-selective, irreversible, orally available EGFR inhibitor. It can overcome T790M-mediated resistance in NSCLC.
价 格:¥电议型 号:TQ0255产 地:中国大陆
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T35548Dynapyrazole ADynapyrazole A
Dynapyrazole A is a specific inhibitor of microtubule dynamin with IC50s of 2.3 and 2.6 μM for dynein 1 and dynein 2-dependent microtubule gliding. Dynapyrazole A inhibits Hedgehog signaling with an IC50 of 1.9 μM.
价 格:¥电议型 号:T35548产 地:中国大陆
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TP1381LHAEGT TFA(852155-81-8 free base)HAEGT TFA(852155 81 8 free base),HAEGT TFA(852155818 free base)
HAEGT TFA is the first N-terminal 1-5 residues of GLP-1 peptide.
价 格:¥电议型 号:TP1381L产 地:中国大陆
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T8553BC-1471IL-1β,Inhibitor,STAM-binding protein,inhibit,BC-1471,BC1471,DUBs,STAMBP,NALP7,BC 1471,Deubiqu
BC-1471 is a STAM-binding protein (STAMBP) deubiquitinase inhibitor. BC-1471 inhibits inflammasome activity of NALP7 (NACHT, LRR and PYD domains-containing protein 7) [1].
价 格:¥电议型 号:T8553产 地:中国大陆
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T35528LTD52 dihydrochloride
TD52 dihydrochloride, an Erlotinib derivative, is an orally active, potent cancerous inhibitor of protein phosphatase 2A (CIP2A) inhibitor. TD52 dihydrochloride mediates the apoptotic effect in triple-negative breast cancer (TNBC) cells via regulating the CIP2A/PP2A/p-Akt signalling pathway. TD52 dihydrochloride indirectly reduced CIP2A by disturbing Elk1 binding to the CIP2A promoter. TD52 dihydrochloride has less p-EGFR inhibition and has potent anti-cancer activity.
价 格:¥电议型 号:T35528L产 地:中国大陆
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TP1651LProinsulin C-peptide human acetateProinsulin C peptide human acetate,Proinsulin Cpeptide human aceta
Proinsulin C-peptide (human) is a polypeptide of 31 amino acid residues that links the A and B chains of proinsulin to ensure proper folding, has biological activity and regulates cellular functions.
价 格:¥电议型 号:TP1651L产 地:中国大陆
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T6554JZL 184MAGL,neurons,JZL-184,inhibit,JZL 184,2-Arachidonoylglycerol,Inhibitor,hydrolysis,Monoacylglyc
JZL 184 is a potent and selective inhibitor of MAGL with IC50 of 8 nM and 4 μM for inhibition of MAGL and FAAH in mouse brain membranes respectively.
价 格:¥电议型 号:T6554产 地:中国大陆
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T8055TFEB activator 1disease,TFEB,Inhibitor,inhibit,mTOR-independent,TFEB activator1,TFEB activator 1,neu
TFEB activator 1 is an activator of transcription factor EB (TFEB) with promise for the prevention or treatment of Alzheimer´s disease.
价 格:¥电议型 号:T8055产 地:中国大陆