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T15404GNE-6468GNE-6468
GNE-6468 is a potent and selective agonist of RORγ(RORc) (EC50: 13 nM for HEK-293 cell).
价 格:¥电议型 号:T15404产 地:美洲
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T15624JNJ-64619178JNJ-64619178
JNJ-64619178 has effective activity In lung cancer. JNJ-64619178 is a selective, orally active, and pseudo-irreversible inhibitor of protein arginine methyltransferase 5 (IC50: 0.14 nM).
价 格:¥电议型 号:T15624产 地:美洲
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T1646FamciclovirFamciclovir,BRL 42810,
Famciclovir is a Herpes Simplex Virus Nucleoside Analog DNA Polymerase Inhibitor. The mechanism of action of famciclovir is as a DNA Polymerase Inhibitor, and DNA Polymerase Inhibitor.
价 格:¥电议型 号:T1646产 地:美洲
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T2084ETP46464ETP46464
ETP-46464 is an effective and specific ATR inhibitor (IC50: 25 nM).
价 格:¥电议型 号:T2084产 地:美洲
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T2433NU7026NU7026,LY293646,DNA-PK Inhibitor II
NU7026 is an effective DNA-PK inhibitor (IC50: 0.23 μM, in cell-free assays), 60-fold selective for DNA-PK than PI3K and no inhibition against both ATM and ATR.
价 格:¥电议型 号:T2433产 地:美洲
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T2452C646C646
C646, a histone acetyltransferase inhibitor, inhibits p300 (Ki: 400 nM, in a cell-free assay).
价 格:¥电议型 号:T2452产 地:美洲
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T4646TA-02TA-02,TA02,TA 02
TA-02 is a p38 MAPK inhibitor with IC50 of 20 nM.TA-02 especially inhibits TGFBR-2.
价 格:¥电议型 号:T4646产 地:美洲
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T4654SLV319SLV319,(±)-BMS6462,(±)-Ibipinabant
SLV319 has been used in trials studying the treatment of Obesity and Obesity and Type 2 Diabetes.
价 格:¥电议型 号:T4654产 地:美洲
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T5646Cinnamic acidCinnamic acid,3-Phenylacrylic acid,β-Phenylacrylic acid
Cinnamic acid has potential use in cancer intervention,The concentration causing a 50% reduction of cell proliferation (IC50) ranged from 1 to 4.5 mM in glioblastoma, melanoma, prostate and lung carcinoma cells.
价 格:¥电议型 号:T5646产 地:美洲
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T8711PF-05186462;化合物PF-05186462PF-05150122;PF-05150122
PF-05186462 (PF-05150122) is a potent, state-dependent, subtype selective Nav1.7 inhibitor with IC50 of 21 nM, no significant activity against Nav1.5.
价 格:¥电议型 号:T8711产 地:中国大陆
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T8646URB937;化合物URB937URB937
URB937 is an inhibitor of FAAH and increases anandamide levels(IC50 : 26.8 nM).
价 格:¥电议型 号:T8646产 地:中国大陆
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T83930SJ 11646;化合物 SJ 11646SJ 11646
SJ 11646, a potent lymphocyte-specific protein tyrosine kinase (LCK) Degrader (PROTAC) with a DC50 of 0.00838 pM, utilizes Dasatinib as the LCK ligand and incorporates a phenyl glutarimide-based cereblon binder. Demonstrating cytotoxicity in both LCK-activated T cell acute lymphoblastic leukemia (T-ALL) cell lines and primary leukemia samples in vitro, SJ 11646 also exhibits anti-leukemic efficacy in vivo within patient-derived xenograft models of T-ALL.
价 格:¥电议型 号:T83930产 地:中国大陆
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T83646(S)-OSMI 3;化合物(S)-OSMI 3Ent-OSMI-3;Ent-OSMI-3
(S)-OSMI 3 (Ent-OSMI-3) has anti-inflammatory and anti-tumour activity and can be used to study diabetes and neurodegenerative diseases.
价 格:¥电议型 号:T83646产 地:中国大陆
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T8357SB-200646;化合物SB-200646SB-200646
SB-200646 is a selective and potent antagonist of 5-HT2B/5-HT2C receptor
价 格:¥电议型 号:T8357产 地:中国大陆
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T82646CYCA-117-70;化合物 CYCA-117-70CYCA-117-70
CYCA-117-70, a DCAF1 ligand with a dissociation constant (K D) of 70 μM, serves as an optimal chemical handle for the recruitment of DCAF1 in PROTACs [1].
价 格:¥电议型 号:T82646产 地:中国大陆
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T81646NPAS3-IN-1;NPAS3制剂1NPAS3-IN-1
NPAS3-IN-1 is a potent inhibitor of NPAS3-ARNT heterodimerization, which regulates NPAS3 transcription by modulating the heterodimerization of NPAS3 with ARNT at the cellular level.
价 格:¥电议型 号:T81646产 地:中国大陆
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T80646Thalidomide-NH-(CH2)2-NH2 TFA;化合物 Thalidomide-NH-(CH2)2-NH2 TFAThalidomide-NH-(CH2)2-NH2 TFA
Thalidomide-NH-(CH2)2-NH2 TFA is an alkyl-modified derivative of Thalidomide serving as a Cereblon ligand to recruit CRBN proteins and a pivotal intermediate in the synthesis of CRBN-based PROTAC molecules for the targeted small molecule PROTACs aimed at SHP2 protein.
价 格:¥电议型 号:T80646产 地:中国大陆
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T79646Anticancer agent 153;化合物 Anticancer agent 153Anticancer agent 153
Anticancer Agent 153 (Compound 3) promotes apoptosis through the generation of Reactive Oxygen Species (ROS) and elevates the loss of Mitochondrial Membrane Potential (MMP), effectively inhibiting cancer cell proliferation [1].
价 格:¥电议型 号:T79646产 地:中国大陆
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T79019JNJ-64264681;化合物 JNJ-64264681JNJ-64264681
JNJ-64264681 is a potent, orally active, selective, and irreversible covalent inhibitor of Bruton´s tyrosine kinase (BTK). This compound demonstrates favorable pharmacokinetic properties and is applicable in the research of cancer and autoimmune diseases [1].
价 格:¥电议型 号:T79019产 地:中国大陆
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T78646Estrogen receptor antagonist 8;Estrogen receptor 拮抗剂 8Estrogen receptor antagonist 8
Estrogen receptor antagonist 8 acts as an estrogen receptor (ER) antagonist with anti-uterine activity and potential anti-tumorigenic activity and can be used to study ovarian dysfunction.
价 格:¥电议型 号:T78646产 地:中国大陆