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T2630PoziotinibPoziotinib,NOV120101,HM781-36B
Poziotinib(NOV120101; HM781-36B) is an irreversible HER1/2/4 inhibitor (IC50s: 3/5/23 nM).
价 格:¥电议型 号:T2630产 地:美洲
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T6072BGT226BGT226,BGT226 maleate,NVP-BGT226 (maleate)
BGT226 (NVP-BGT226) is a class I PI3K/mTOR inhibitor for PI3Kα/β/γ (IC50: 4/63/38 nM) .
价 格:¥电议型 号:T6072产 地:美洲
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T6173BI 2536BI 2536
BI2536 is an effective Plk1 inhibitor (IC50: 0.83 nM). It has 4- and 11-fold greater selectivity than Plk2 and Plk3.
价 格:¥电议型 号:T6173产 地:美洲
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T6428BV6BV6
BV6 is an antagonist of c-IAP1 and XIAP, members of the inhibitors of apoptosis (IAP) family.
价 格:¥电议型 号:T6428产 地:美洲
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T8758Poziotinib hydrochloride;波齐替尼盐酸盐HM 781-36B hydrochloride|||NOV120101 hydrochloride;HM 781-36B hydroc
Poziotinib hydrochloride irreversibly inhibits EGFR (HER1 or ErbB1), including EGFR mutants, HER2, and HER4, thereby inhibiting the proliferation of tumor cells that overexpress these receptors. It is an orally bioavailable, quinazoline-based pan epidermal growth factor receptor (EGFR or HER) inhibitor with potential antineoplastic activity.
价 格:¥电议型 号:T8758产 地:中国大陆
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T8515Osoresnontrine;化合物BI-409306BI-409306;BI-409306
Osoresnontrine (BI-409306) is a potent and selective inhibitor of PDE9A (IC50 of 52 nM),and can be used in the research of memory
价 格:¥电议型 号:T8515产 地:中国大陆
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T8474Dabrafenib Mesylate;甲磺酸达拉非尼GSK 2118436B|||GSK2118436 Mesylate;达帕菲尼甲磺酸盐|||甲磺酸达拉非尼|||GSK 2118436B|||GS
Dabrafenib Mesylate (GSK2118436 Mesylate) is a B-Raf inhibitor(IC50s of 0.6 and 5.0 nM for RafV600E and c-Raf, respectively).
价 格:¥电议型 号:T8474产 地:中国大陆
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T83554(4R,4aS,5aS,6aR,6bS,7aR)-4-Hydroxy-3,6b-dimethyl-5-methylene-4,4a,5,5a,6,6a,7,7a-octahydrocyclopropa
(4R,4aS,5aS,6aR,6bS,7aR)-4-Hydroxy-3,6b-dimethyl-5-methylene-4,4a,5,5a,6,6a,7,7a-octahydrocyclopropa[2,3]indeno[5,6-b]furan-2(6bH)-one is a sesquiterpene lactone featuring a complex bicyclic structure [1].
价 格:¥电议型 号:T83554产 地:中国大陆
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T82910Bcl-2-IN-16;化合物 Bcl-2-IN-16Bcl-2-IN-16
Bcl-2-IN-16 is a Bcl-2 (B-cell lymphoma 2) inhibitor [1].
价 格:¥电议型 号:T82910产 地:中国大陆
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T82849BMS-496;化合物 BMS-496BMS-496
BMS-496 is a dual DGKα/ζ lipid kinase inhibitor exhibiting IC50 values of 0.09 μM (DGKα) and 0.006 μM (DGKζ) [1].
价 格:¥电议型 号:T82849产 地:中国大陆
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T82502Efaprinermin alfa;化合物 Efaprinermin alfaOMP-336B11;OMP-336B11
Efaprimermin alfa (OMP-336B11) is a human monoclonal antibody that targets TNFRSF18, and functions as a GITR ligand-Fc fusion protein [1].
价 格:¥电议型 号:T82502产 地:中国大陆
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T79830B-Raf IN 16;B-Raf 抑制剂 16B-Raf IN 16
B-Raf IN 16, a BRAF inhibitor, belongs to cyclic iminopyrimidine derivatives and can be used for cancer or tumour research.
价 格:¥电议型 号:T79830产 地:中国大陆
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T79313BI 7446;化合物 BI 7446BI 7446
BI 7446 is a potent and selective cyclic dinucleotide (CDN)-based stimulator of interferon genes (STING) agonist capable of activating all five STING variants in cells, thus inducing tumor-specific immune-mediated tumor rejection. This compound is utilized in immuno-oncology research [1].
价 格:¥电议型 号:T79313产 地:中国大陆
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T78989BET-IN-16;化合物 BET-IN-16BET-IN-16
BET-IN-16 (Comp I), a bromodomain and extra-terminal (BET) inhibitor, demonstrates anticancer activity by impeding the growth of prostate cancer cells. It exhibits potent inhibitory effects with half-maximal inhibitory concentration (IC50) values of 0.043 μM for LNCaP cells and 0.034 μM for 22Rv1 cells [1].
价 格:¥电议型 号:T78989产 地:中国大陆
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T78982BK60106;化合物 BK60106BK60106
BK60106, a CD99 inhibitor, selectively targets and binds to the extracellular domain of CD99, effectively inducing apoptosis in Ewing sarcoma (ES) cells with minimal associated DNA damage [1].
价 格:¥电议型 号:T78982产 地:中国大陆
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T78933BD-9136;化合物 BD-9136BD-9136
BD-9136, a highly selective BRD4 degrader, demonstrates the capability to inhibit tumor growth without inducing adverse effects in mice, showing potential for cancer research [1].
价 格:¥电议型 号:T78933产 地:中国大陆
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T78695BChE-IN-16;化合物 BChE-IN-16BChE-IN-16
BChE-IN-16 (compound 87) is a potent inhibitor of human butyrylcholinesterase (hBChE) exhibiting an inhibition concentration half-maximum (IC50) of 3.8 nM. It demonstrates low cytotoxicity and potential for central nervous system (CNS) permeability, along with unique adaptability, rendering it a valuable tool for research into Alzheimer´s disease (AD).
价 格:¥电议型 号:T78695产 地:中国大陆
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T77713BTM-3566;化合物BTM-3566BTM 3566|||BTM3566;BTM 3566|||BTM3566
BTM-3566 activates the ISR through the mitochondrial protease OMA1.BTM-3566 induces apoptosis in cancer cells. BTM-3566 overactivates the mitochondrial ISR to study DLBCL.
价 格:¥电议型 号:T77713产 地:中国大陆
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T75707BIM-26226;化合物 BIM-26226BIM-26226
BIM-26226, a gastrin-releasing peptide, serves as a potent and selective antagonist to the bombesin receptor, effectively inhibiting BN- or GRP-stimulated amylase release with IC50 values in the nanomolar range. It is utilized in cancer research [1] [2].
价 格:¥电议型 号:T75707产 地:中国大陆