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T18988FITC-DextranFITC-Dextran
FITC-Dextran (MW 10000) is a marker consisting of coupling fluorescein-isothiocyanate to dextran (10 kDa). FITC-Dextran can be used to determine ion, solute, and protein permeability of the blood-brain barrier (BBB) based on the size of the dextran used.
价 格:¥电议型 号:T18988产 地:美洲
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T1988DuvelisibDuvelisib,INK1197,IPI-145
Duvelisib is an orally bioavailable, highly selective and potent small molecule inhibitor of the delta and gamma isoforms of phosphoinositide-3 kinase (PI3K) with potential immunomodulating and antineoplastic activities.
价 格:¥电议型 号:T1988产 地:美洲
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T2081LY2409881 trihydrochlorideLY2409881 trihydrochloride,LY2409881,
LY2409881 trihydrochloride is a novel specific inhibitor of IKK2 (IC50: 30 nM); IC50 for IKK1 and other common kinases is at least one log higher.
价 格:¥电议型 号:T2081产 地:美洲
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T4988BoceprevirBoceprevir,SCH 503034,EBP 520
Boceprevir is a novel, potent, highly selective, orally bioavailable HCV NS3 protease inhibitor with Ki of 14 nM in both enzyme assay and EC90 of 350 nM in cell-based replicon assay.
价 格:¥电议型 号:T4988产 地:美洲
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T82988AP-C7;化合物 AP-C7AP-C7
AP-C7 is a selective inhibitor of cGMP-dependent protein kinase II (cGKII) with a pIC50 value of 5.0, demonstrating only weak inhibition of cGKII-dependent anion secretion [1].
价 格:¥电议型 号:T82988产 地:中国大陆
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T81988Kanshone C;化合物 Kanshone CKanshone C
Kanshone C, a sesquiterpenoid found in the roots of Nardostachys chinensis [1], exhibits noteworthy biological properties.
价 格:¥电议型 号:T81988产 地:中国大陆
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T81052T988C;化合物 T988C(+)-T988C;(+)-T988C
T988C, a heptacyclic epidithiodioxopiperazine (ETP) natural product, exhibits potent cytotoxicity against cultured P388 leukemia cells [1].
价 格:¥电议型 号:T81052产 地:中国大陆
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T80988Thymolphthalexon tetrasodium;化合物 Thymolphthalexon tetrasodiumThymolphthalexon tetrasodium
Thymolphthalexon (tetrasodium) is an organic thioxanthone derivative utilized as a biochemical assay reagent due to its potent antioxidant properties. It plays a significant role in researching free radical response, oxidative stress, and aging. Furthermore, Thymolphthalexon serves as a photosensitizer in photodynamic therapy, contributing to the treatment of cancer and various other diseases.
价 格:¥电议型 号:T80988产 地:中国大陆
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T79988Cytochalasin R;化合物 Cytochalasin RCytochalasin R
Cytochalasin R (compound 17), an analogue of cytochalasin, is derived from the endophytic fungus Phomopsis sp. xz-18 and exhibits potential antifungal activity [1].
价 格:¥电议型 号:T79988产 地:中国大陆
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T79888EGFR-IN-87;化合物 EGFR-IN-87EGFR-IN-87
EGFR-IN-87 is an EGFR tyrosine kinase inhibitor with potent inhibitory activity, exhibiting IC50 values of 3.1 nM, 1.3 nM, and 7.1 nM against EGFR_d746-750, EGFR_L858R/T790M, and EGFR_WT, respectively, in A431 cells. It is utilized in research pertaining to cancer diseases [1].
价 格:¥电议型 号:T79888产 地:中国大陆
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T79887Tubulin polymerization-IN-49;化合物 Tubulin polymerization-IN-49Tubulin polymerization-IN-49
Tubulin polymerization-IN-49 (compound 12d), a potent inhibitor of tubulin polymerization, binds to the colchicine site on tubulin, subsequently inducing cell cycle arrest at the G2/M phase and triggering apoptosis. This compound exhibits anticancer activity by preventing tumor generation and inhibiting tumor proliferation and angiogenesis [1].
价 格:¥电议型 号:T79887产 地:中国大陆
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T79886HSD17B13-IN-3;化合物 HSD17B13-IN-3HSD17B13-IN-3
HSD17B13-IN-3 (compound 2) is a potent inhibitor of hydroxysteroid 17?-dehydrogenase 13 (HSD17B13), lacking cellular experimental activity [1].
价 格:¥电议型 号:T79886产 地:中国大陆
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T79885HSD17B13-IN-2;化合物 HSD17B13-IN-2HSD17B13-IN-2
HSD17B13-IN-2 (compound 1) serves as a potent inhibitor of hydroxysteroid 17?-dehydrogenase 13 (HSD17B13) with demonstrable activity in cellular experiments [1].
价 格:¥电议型 号:T79885产 地:中国大陆
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T79884D-4-77;化合物 D-4-77D-4-77
D-4-77 is a potent inhibitor of SARS-CoV-2 Mpro, exhibiting an IC 50 of 0.95 μM, and possesses antiviral activity with an EC 50 of 0.49 μM. Furthermore, it suppresses SARS-CoV-2 Mpro-induced antagonism of the host NF-κB innate immune response [1].
价 格:¥电议型 号:T79884产 地:中国大陆
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T798839-Chloromethyl-10-hydroxy-11-F-Camptothecin;化合物 9-Chloromethyl-10-hydroxy-11-F-Camptothecin9-Chlorom
9-Chloromethyl-10-hydroxy-11-F-Camptothecin, a novel derivative of camptothecin, functions as a DNA topoisomerase I (Topo I) inhibitor with potential applications in anticancer research [1].
价 格:¥电议型 号:T79883产 地:中国大陆
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T79882JAK-IN-31;化合物 JAK-IN-31JAK-IN-31
JAK-IN-31 (Example 75), a JAK inhibitor, demonstrates IC50 values of ≤0.01 ?M for JAK1, ≤0.01 ?M for JAK2, 0.01-0.1 ?M for JAK3, and ≤0.01 ?M for Tyk2, indicating potent activity across these targets. It is utilized in cancer research [1].
价 格:¥电议型 号:T79882产 地:中国大陆
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T79881CDK7-IN-25;化合物 CDK7-IN-25CDK7-IN-25
CDK7-IN-25 (CY-16-1) is a potent CDK7 inhibitor with an IC50 value of less than 1nM, utilized in cancer research [1].
价 格:¥电议型 号:T79881产 地:中国大陆
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T79880FGFR4-IN-16;化合物 FGFR4-IN-16FGFR4-IN-16
FGFR4-IN-16 (CY-15-2) is a covalent inhibitor targeting FGFR-4, utilized in cancer research [1].
价 格:¥电议型 号:T79880产 地:中国大陆