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T79060MOR agonist-1；化合物 MOR agonist-1MOR agonist-1
MOR Agonist-1 is a μ-opioid receptor (MOR) agonist noted for its potent analgesic properties and is utilized in research concerning pain and associated disorders [1].
价 格：￥电议型 号：T79060产 地：中国大陆
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T79023CaSR antagonist-1；化合物 CaSR antagonist-1CaSR antagonist-1
CaSR Antagonist-1 is a potent inhibitor of the calcium-sensing receptor (CaSR) with an inhibitory concentration (IC50) of 50 nM, suitable for the investigation of diseases related to dysregulated bone or mineral homeostasis, including osteoporosis [1].
价 格：￥电议型 号：T79023产 地：中国大陆
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T78954hNTS1R agonist-1；化合物 hNTS1R agonist-1hNTS1R agonist-1
Compound 10, an hNTS1R agonist-1, acts as a full agonist with a strong affinity for hNTS1R (K i: 6.9 nM), showing the ability to cross the blood-brain barrier (BBB). It not only enhances motor function but also improves memory in a mouse model of Parkinson´s disease (PD). Additionally, this compound is an analog of Neurotensin(8-13) and demonstrates neuroprotective properties [1].
价 格：￥电议型 号：T78954产 地：中国大陆
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T78825D4R agonist-1；D4R激动剂1D4R agonist-1
D4R agonist-1 is a selective and potent D4R partial agonist (Ki:2.2 nM).D4R agonist-1 can be used to study neurological diseases.
价 格：￥电议型 号：T78825产 地：中国大陆
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T77835Glucocorticoid receptor agonist-1 phosphate Gly-Glu-Br；化合物 Glucocorticoid receptor agonist-1 phospha
Glucocorticoid Receptor Agonist-1 Phosphate (Gly-Glu-Br) is an antibody-drug conjugate (ADC) linker utilized in the synthesis of ABBV-154, ABBV-927, ABBV-368, and related analogs [1].
价 格：￥电议型 号：T77835产 地：中国大陆
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T75150GIP/GLP-1 dual receptor agonist-1；化合物 GIP/GLP-1 dual receptor agonist-1GIP/GLP-1 dual receptor agoni
GIP/GLP-1 dual receptor agonist-1 (compound 4), a receptor agonist for both GIP and GLP-1, shows potential for the research of metabolic disorders and fatty liver diseases, such as nonalcoholic steatohepatitis (NASH) and nonalcoholic fatty liver disease (NAFLD) [1].
价 格：￥电议型 号：T75150产 地：中国大陆
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T75130Glucocorticoid receptor agonist-1 phosphate Ala-Ala-Br；化合物 Glucocorticoid receptor agonist-1 phospha
Glucocorticoid Receptor Agonist-1 Phosphate Ala-Ala-Br is a drug-linker conjugate for antibody-drug conjugates (ADCs), serving as a reaction reagent in the creation of anti-CD40 antibody agent conjugates [1].
价 格：￥电议型 号：T75130产 地：中国大陆
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T75016Glucocorticoid receptor agonist-1 phosphate Ala-Ala-Mal；化合物 Glucocorticoid receptor agonist-1 phosph
Glucocorticoid Receptor Agonist-1 Phosphate Ala-Ala-Mal functions as a glucocorticoid receptor agonist, utilized in the formulation of anti-CD40 antibody agent conjugates (ADC). It serves as a research tool for exploring inflammation and immune regulation [1].
价 格：￥电议型 号：T75016产 地：中国大陆
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T74854GluN2B-NMDAR antagonist-1；化合物 GluN2B-NMDAR antagonist-1GluN2B-NMDAR antagonist-1
GluN2B-NMDAR Antagonist-1, an orally active compound, functions as a GluN2B-NMDAR antagonist with neuroprotective properties. It is applicable in the research of ischemic injury [1].
价 格：￥电议型 号：T74854产 地：中国大陆
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T74708β2AR/M-receptor agonist-1；化合物 β2AR/M-receptor agonist-1β2AR/M-receptor agonist-1
β2AR/M-receptor agonist-1 (example 131), a muscarinic antagonist and β2 adrenoceptor agonist (MABA), exhibits dual potency towards β2 adrenoceptor and muscarinic receptor. It demonstrates a significant affinity for the β2 adrenoceptor, indicated by an EC50 value of 9.2 nM, and for the muscarinic receptor with a Ki value of 30.2 nM. Furthermore, its MABA activity is highlighted by an EC50 value of 4.0 nM [1].
价 格：￥电议型 号：T74708产 地：中国大陆
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T74606A2A/A3u00A0AR antagonist-1；化合物 A2A/A3u00A0AR antagonist-1A2A/A3u00A0AR antagonist-1
Compound 23, designated as A2A/A3 AR antagonist-1, is a dual fluorescent ligand targeting A2A and A3 adenosine receptors (AR), exhibiting dissociation constants (Ki) of 90 nM for hA2A AR and 31.8 nM for hA3 AR, respectively [1].
价 格：￥电议型 号：T74606产 地：中国大陆
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T74268STING agonist-13；化合物 STING agonist-13STING agonist-13
STING Agonist-13, a stimulator of interferon genes (STING) agonist, enhances cancer immunity through STING-mediated immune activation. It activates STING downstream signaling to promote type I interferon immune responses, significantly reduces tumor volume, and exhibits immunological memory-derived cancer inhibition [1].
价 格：￥电议型 号：T74268产 地：中国大陆
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T74267STING agonist-17；化合物 STING agonist-17STING agonist-17
STING agonist-17 (compound 4a) is a highly potent stimulator of the STING pathway, exhibiting an IC 50 of 0.062 nM. It demonstrates significant anti-cancer properties, promoting tumor immunization [1].
价 格：￥电议型 号：T74267产 地：中国大陆
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T74116Glucocorticoid receptor agonist-1 Ala-Ala-Mal；化合物 Glucocorticoid receptor agonist-1 Ala-Ala-MalGluco
Glucocorticoid receptor agonist-1 Ala-Ala-Mal (compound 88), a glucocorticosteroid and glucocorticoid receptor agonist, can be conjugated with Adalimumab to formulate an ADC [1].
价 格：￥电议型 号：T74116产 地：中国大陆
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T73746diABZI STING agonist-1；化合物 diABZI STING agonist-1diABZI STING agonist-1
DiABZI STING Agonist-1 is a selective receptor agonist for the stimulator of interferon genes (STING), demonstrating efficacy with EC50 values of 130 nM and 186 nM in human and mouse models, respectively.
价 格：￥电议型 号：T73746产 地：中国大陆
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T72626A2AR-antagonist-1；化合物 A2AR-antagonist-1A2AR-antagonist-1
A2AR-antagonist-1 (compound 38), an orally active adenosine A2A receptor antagonist with an IC50 value of 29 nM, demonstrates anti-tumor properties and stability in mouse liver microsomes (t1/2 = 86.1 min). Additionally, it activates T cells by inhibiting immunosuppressive molecules (LAG-3 and TIM-3) and promoting expression of effector molecules (GZMB, IFNG, and IL-2) [1].
价 格：￥电议型 号：T72626产 地：中国大陆
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T72473NOD1/2 antagonist-1；化合物 NOD1/2 antagonist-1NOD1/2 antagonist-1
NOD1/2 Antagonist-1 is a potent dual inhibitor of nucleotide-binding oligomerization domain-like receptors 1 and 2 (NOD1/2), displaying inhibitory concentrations (IC50) of 1.13 μM for NOD1 and 0.77 μM for NOD2. It exhibits an acceptable half-life (T1/2) of 67.6 minutes. Additionally, NOD1/2 Antagonist-1 enhances the antitumor efficiency of Paclitaxel (PTX).
价 格：￥电议型 号：T72473产 地：中国大陆
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T72294S1P5 receptor agonist-1；化合物 S1P5 receptor agonist-1S1P5 receptor agonist-1
S1P5 Receptor Agonist-1 (example 6) is a highly potent and selective agonist for the S1P5 receptor, exhibiting an EC50 value of 20 nM.
价 格：￥电议型 号：T72294产 地：中国大陆
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T71663FFA3 agonist 1；化合物 FFA3-Agonist-1FFA3 agonist 1
FFA3 Agonist 1, a potent agonist of the free fatty acid receptor 3 (FFA3), plays a crucial role in mediating the health-promoting effects of the intestinal microbiota through the activation of FFA3.
价 格：￥电议型 号：T71663产 地：中国大陆
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T64715FFA3-Agonist-1；化合物 FFA3-Agonist-1FFA3-Agonist-1
FFA3-Agonist-1 has a wide range of applications in life science related research.
价 格：￥电议型 号：T64715产 地：中国大陆
