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  • T62274AChE/BChE-IN-2；化合物 AChE/BChE-IN-2AChE/BChE-IN-2

    AChE/BChE-IN-2 (Compound 13b) is a potent inhibitor of AChE/BChE with IC50 values of 0.96 ± 0.14 μM and 1.23 ± 0.23 μM for AChE and BChE, respectively.

    价 格：￥电议型 号：T62274产 地：中国大陆

  • T61994AChE/BChE-IN-8；化合物 AChE/BChE-IN-8AChE/BChE-IN-8

    AChE/BChE-IN-8 (Compound 5a) is an uncompetitive AChE and mixed BChE inhibitor. AChE/BChE-IN-8 shows Ki of 0.788 μM and 2.364 μM against Electrophorus electricus AChE (EeAChE) and equine BChE (eqBChE), respectively. AChE/BChE-IN-8 has blood-brain barrier permeability and low cytotoxicity.

    价 格：￥电议型 号：T61994产 地：中国大陆

  • T61969AChE/BChE-IN-10；化合物AChE/BChE-IN-10AChE/BChE-IN-10

    AChE/BChE-IN-10 is a potent dual inhibitor of AChE and BChE with IC50 values of 0.176, and 0.47 μM, respectively. AChE/BChE-IN-10 exhibits good blood brain barrier permeability. AChE/BChE-IN-10 can inhibit Aβ-aggregation.

    价 格：￥电议型 号：T61969产 地：中国大陆

  • T61785BChE-IN-6；化合物 BChE-IN-6BChE-IN-6

    BChE-IN-6 (compound 12) is a highly effective inhibitor of BChE, showcasing a Ki value of 0.182 μM. Notably, BChE-IN-6 exhibits significant chelating abilities towards Zn 2+. Due to these characteristics, BChE-IN-6 serves as a valuable tool for researchers in the field of Alzheimer´s disease (AD) [1].

    价 格：￥电议型 号：T61785产 地：中国大陆

  • T61669BChE-IN-4；化合物 BChE-IN-4BChE-IN-4

    BChE-IN-4 is a highly potent inhibitor of the enzyme butyrylcholinesterase, capable of crossing the blood-brain barrier. It effectively reduces learning and memory impairments resulting from a deficiency in cholinergic activity in a mouse model. BChE-IN-4 holds promise for further investigation in the field of Alzheimer´s disease research [1].

    价 格：￥电议型 号：T61669产 地：中国大陆

  • T61408BChE-IN-2；化合物 BChE-IN-2BChE-IN-2

    BChE-IN-2 (compound 22) is a highly effective inhibitor of BChE, exhibiting a Ki value of 0.099 μM. This compound represents a promising pyrimidine and pyridine derivative for investigating Alzheimer´s disease (AD). [1]

    价 格：￥电议型 号：T61408产 地：中国大陆

  • T61397AChE/BChE-IN-9；化合物 AChE/BChE-IN-9AChE/BChE-IN-9

    AChE/BChE-IN-9 (Compound 7a) is a potent orally active inhibitor of AChE and BChE, with IC50 values of 5.74 μM and 14.05 μM against hAChE and eqBChE, respectively. It also demonstrates effective antioxidant activity, with an IC50 value of 57.35 μM. Additionally, AChE/BChE-IN-9 exhibits the ability to chelate iron and modulate the aggregation of amyloid β 1-42. Notably, AChE-IN-16 has the ability to cross the blood-brain barrier [1].

    价 格：￥电议型 号：T61397产 地：中国大陆

  • T61342BChE-IN-13；化合物 BChE-IN-13BChE-IN-13

    BChE-IN-13 (Compound 17c) is an orally active, potent, and selective inhibitor of Butyrylcholinesterase (BChE). It exhibits IC50 values of 0.22 μM and 0.016 μM for eqBChE and hBChE, respectively. BChE-IN-13 demonstrates the capability to enhance memory and cognitive impairments, making it valuable for Alzheimer´s disease (AD) research [1].

    价 格：￥电议型 号：T61342产 地：中国大陆

  • T61206AChE/BChE/BACE-1-IN-1；化合物 AChE/BChE/BACE-1-IN-1AChE/BChE/BACE-1-IN-1

    AChE/BChE/BACE-1-IN-1 (Compound 4k) is an orally active inhibitor that targets acetylcholinesterase (AChE), butyrylcholinesterase (BChE), and β-site amyloid precursor protein cleaving enzyme 1 (BACE-1). It displays IC50 values of 0.058 μM, 0.082 μM, and 0.115 μM against hAChE, hBChE, and hBACE-1, respectively. AChE/BChE/BACE-1-IN-1 exhibits significant binding affinity with PAS-AChE, excellent ability to cross the blood-brain barrier, potential disassembly of amyloid-beta (Aβ) aggregates, and ne

    价 格：￥电议型 号：T61206产 地：中国大陆

  • T61050BChE-IN-7；化合物 BChE-IN-7BChE-IN-7

    BChE-IN-7 (compound 13) is a potent, selective, and reversible inhibitor of AChE and BChE. The IC50 value of BChE-IN-7 for BChE is 0.06 μM. BChE-IN-7 is able to cross the blood-brain barrier and protect neuronal-like cells from toxic Aβ-species [1].

    价 格：￥电议型 号：T61050产 地：中国大陆

  • T60983BChE-IN-14；化合物 BChE-IN-14BChE-IN-14

    BChE-IN-14 (compound 19c) can restore cognitive impairment in vivo that can be used in the Alzheimer’s disease research. BChE-IN-14 has primary cell safety and good blood brain barrier permeability. BChE-IN-14 is a selective inhibitor of butyrylcholinesterase (BChE) with IC50 values of 0.011 μM and 0.23 μM for hBChE and eqBChE, respectively [1].

    价 格：￥电议型 号：T60983产 地：中国大陆

  • T60891AChE/BChE/MAO-B-IN-1；化合物AChE/BChE/MAO-B-IN-1AChE/BChE/MAO-B-IN-1

    AChE/BChE/MAO-B-IN-1 is a reversible, non-time-dependent inhibitor of AChE, BChE and MAO-B that crosses the blood-brain barrier and exhibits inhibitory effects on hAChE, hBChE and hMAO-B with IC50s of 7.31, 0.56 and 26.1 μM, respectively. 1 had a neuroprotective effect and was not significantly cytotoxic.

    价 格：￥电议型 号：T60891产 地：中国大陆

  • T60831AChE/BChE-IN-3 hydrochloride；化合物 AChE/BChE-IN-3 hydrochlorideAChE/BChE-IN-3 hydrochloride

    AChE/BChE-IN-3 (BMC-1) hydrochloride is an AChE and BChE dual inhibitor. The IC50 values of AChE/BChE-IN-3 against equine serum BChE (eqBChE) and electric eel AChE (elAChE) is 0.383 μM and 6.08 μM, respectively [1].

    价 格：￥电议型 号：T60831产 地：中国大陆

  • T60720AChE/BChE-IN-4；化合物 AChE/BChE-IN-4AChE/BChE-IN-4

    AChE/BChE-IN-4 (BMC-3) is an AChE and BChE dual inhibitor that can cross the BBB. The IC 50 values of AChE/BChE-IN-4 for human AChE (hAChE) and human BChE (hBChE) are 792 nM and 2.2 nM, respectively[1].

    价 格：￥电议型 号：T60720产 地：中国大陆

  • T60691AChE/BChE/BACE-1-IN-2；化合物 AChE/BChE/BACE-1-IN-2AChE/BChE/BACE-1-IN-2

    AChE/BChE/BACE-1-IN-2 (Compound 4o) exhibits remarkable antioxidant potential and considerable binding capability towards PAS-AChE. AChE/BChE/BACE-1-IN-2 is an orally active AChE, BACE-1 and BChE inhibitor with IC 50 values of 0.069, 0.097 and 0.127 μM against hAChE, hBACE-1 and hBChE, respectively. AChE/BChE/BACE-1-IN-2 shows potential disassembly of Aβ aggregates and neuroprotective activity against Aβ-induced stress with excellent brain permeation [1].

    价 格：￥电议型 号：T60691产 地：中国大陆

  • T60529AChE/BChE-IN-3；化合物 AChE/BChE-IN-3AChE/BChE-IN-3

    AChE/BChE-IN-3 (BMC-1) is an AChE and BChE dual inhibitor with IC 50 values of 6.08 μM for electric eel AChE (elAChE) and 0.383 μM for equine serum BChE (eqBChE), respectively [1].

    价 格：￥电议型 号：T60529产 地：中国大陆

  • T41008BODIPY-Cholesterol；化合物BODIPY-CholesterolBCh2；BCh2

    BODIPY-Cholesterol (TF-Chol) is a cholesterol analog with a fluorescent BODIPY motif and cellular permeability, and is a novel BODIPY cholesterol probe.BODIPY-Cholesterol can be used to study intracellular sterol uptake and interorganelle sterol flux.

    价 格：￥电议型 号：T41008产 地：中国大陆

  • T38302Chrysomycin B金黄霉素BChrysomycin B

    Chrysomycin B is an antibiotic isolated from Streptomyces sp. Chrysomycin B induces DNA damage and inhibits topoisomerase II in the human lung adenocarcinoma A549 cell line.

    价 格：￥电议型 号：T38302产 地：中国大陆

  • T36814Chevalone B；Chevalone BChevalone B

    Chevalone B is a meroterpenoid originally isolated from the fungus E. chevalieri. It is cytotoxic to KB and NCI-H187 cells with IC50 values of 2.9 and 9.8 μg/ml, respectively.

    价 格：￥电议型 号：T36814产 地：中国大陆

  • T33891PBI-1393；化合物 T33891PBI1393|||BCH1393|||BCH 1393|||BCH-1393|||PBI 1393；PBI1393|||BCH1393|||BCH 1393||

    PBI-1393 can be used as an enhancer for Th1 type cytokine production and primary T cell activation.

    价 格：￥电议型 号：T33891产 地：中国大陆

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