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T81624Obexelimab;化合物 ObexelimabXmAb5871;XmAb5871
Obexelimab (XmAb5871) is a humanized Fc-engineered anti-CD19 antibody with enhanced affinity for FcγRIIb, utilized in the study of autoimmune diseases [1].
价 格:¥电议型 号:T81624产 地:中国大陆
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T80761XQ2B;化合物 XQ2BXQ2B
XQ2B is a cGAS inhibitor that impedes protein-DNA interactions and phase separation. It suppresses antiviral immune responses induced by herpes simplex virus 1 (HSV-1) and augments HSV-1 infection in both in vitro and in vivo settings [1].
价 格:¥电议型 号:T80761产 地:中国大陆
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T80726Ziralimumab;化合物 ZiralimumabABX-RB2;ABX-RB2
Ziralimumab (ABX-RB2), an anti-human CD147/BSG monoclonal antibody, is employed for immunosuppression [1].
价 格:¥电议型 号:T80726产 地:中国大陆
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T78072Prohexadione calcium;化合物 Prohexadione calciumBX-112;BX-112
Prohexadione calcium (BX-112) is a plant growth regulator that inhibits gibberellin biosynthesis in plants [1] [2].
价 格:¥电议型 号:T78072产 地:中国大陆
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T76953Xeligekimab;化合物 XeligekimabXeligekimab
Xeligekimab (GR 1501) is a humanized monoclonal antibody targeting human interleukin 17A (IL-17A) to inhibit the pro-inflammatory cascade [1].
价 格:¥电议型 号:T76953产 地:中国大陆
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T75569Xerophilusin B;化合物 Xerophilusin BXerophilusin B
Xerophilusin B, isolated from Isodon xerophilus as an anticancer agent, demonstrates antiproliferative effects on esophageal squamous cell carcinoma (ESCC) cell lines. It induces G2/M cell cycle arrest and mediates apoptosis [1].
价 格:¥电议型 号:T75569产 地:中国大陆
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T74867UBX1325;化合物 UBX1325UBX1325
UBX1325, a Bcl-xL inhibitor, enhances apoptosis in senescent cells, serving as an effective anti-aging agent. It holds potential for age-related eye disease research, including diabetic macular oedema (DME), age-related macular degeneration (AMD), and diabetic retinopathy (DR) [1].
价 格:¥电议型 号:T74867产 地:中国大陆
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T71905BX-513 HCl;化合物 BX-513 HClBX-513 HCl
BX-513 HCl is a selective CCR1 receptor antagonist.
价 格:¥电议型 号:T71905产 地:中国大陆
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T71837HBX;化合物 HBXHBX
HBX is a deubiquitinase inhibitor. It inhibits HAdV type 5 (species C, HAdV-C5) replication and oncogenic transformation through inhibition of the cellular pro-viral factor ubiquitin-specific protease 7 (USP7). HBX also significantly inhibits virus genome replication and progeny release of all adenovirus types tested, with the exception of types 12 and 31, from tested species.
价 格:¥电议型 号:T71837产 地:中国大陆
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T70578BX-795 hydrochloride;化合物 BX-795 hydrochlorideBX-795 hydrochloride
BX-795 hydrochloride is a TBK1 and IKKε inhibitor. BX-795 is a potential maternal embryonic leucine zipper kinase inhibitor.
价 格:¥电议型 号:T70578产 地:中国大陆
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T7014Voxtalisib;化合物VoxtalisibXL765|||SAR245409;XL765|||SAR245409
Voxtalisib (XL765) (SAR245409, XL765) is a dual inhibitor of mTOR/PI3K, mostly for p110γ with IC50 of 9 nM; also inhibits DNA-PK and mTOR. Phase 1/2.
价 格:¥电议型 号:T7014产 地:中国大陆
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T68876BXL0124;化合物 BXL0124BXL0124
BXL0124 is a gemini vitamin D analog which targets CD44-STAT3 signaling and inhibits breast cancer invasion.
价 格:¥电议型 号:T68876产 地:中国大陆
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T68319MBX-8025 lysine anhydrous;化合物 MBX-8025 lysine anhydrousMBX-8025 lysine anhydrous
MBX-8025 lysine anhydrous is a selective PPAR-delta agonist.
价 格:¥电议型 号:T68319产 地:中国大陆
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T5821BC-1215化合物BC-1215Ligands for E3 Ligase|||E3 ligase-recruiting Moiety|||F-box protein 3 (Fbxo3)|||Inh
BC-1215 is an inhibitor of F-box protein 3 (FBXO3, a ubiquitin E3 ligase component, IC50=0.9 μg/mL for IL-1β release).
价 格:¥电议型 号:T5821产 地:中国大陆
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T5353ABX-1431;化合物ABX-1431Elcubragistat;Elcubragistat
ABX-1431 (Elcubragistat) is a selective and orally available CNS-penetrant monoacylglycerol lipase (MAGL/MGLL) inhibitor (IC50: 14 nM).
价 格:¥电议型 号:T5353产 地:中国大陆
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T4628Seladelpar;化合物MBX 8025MBX 8025;MBX 8025
Seladelpar (MBX 8025) has been used in trials studying the treatment of Hyperlipidemia.
价 格:¥电议型 号:T4628产 地:中国大陆
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T4046BX517;化合物BX517PDK1 inhibitor 2|||BX 517|||BX-517;PDK1 inhibitor 2|||BX 517|||BX-517
BX517 (PDK1 inhibitor 2) is a potent and selective inhibitor of PDK1.
价 格:¥电议型 号:T4046产 地:中国大陆
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T39432HKOCl-4;HKOCl-4HKOCl-4|||BXY2142;HKOCl-4|||BXY2142
HKOCl-4 (BXY2142) is a rhodol-based yellow fluorescent probe that demonstrates exceptional sensitivity and selectivity in detecting hypochlorous acid. Its absorption wavelength is significantly longer than that of fluorescein-based probes, and it exhibits better pH stability. Notably, HKOCl-4 exhibits excitation at 530 nm and emission at 557 nm.
价 格:¥电议型 号:T39432产 地:中国大陆
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T37561BX-320;BX-320BX-320
BX-320 is an inhibitor of the serine/threonine kinase 3-phosphoinositide-dependent protein kinase 1 (PDK1; IC50= 30 nM).1It is selective for PDK1 over a panel of 10 additional kinases (IC50s = >820 nM for all). BX-320 inhibits Akt and p70S6K1 phosphorylation in PC3 cells (IC50s = 1-3 μM). It induces apoptosis in, and inhibits the growth of, MDA-MB-468 breast cancer cells (IC50s = 0.5 and 0.6 μM, respectively), as well as inhibits cell growth in a panel of cancer cells (IC50s = 0.12-1.2 μM). BX-3
价 格:¥电议型 号:T37561产 地:中国大陆
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T35961Prostaglandin Bx;Prostaglandin BxProstaglandin Bx
PGBx is a mixture of oligomers of PGB1 with a molecular weight of 1,000-1,500. It has antioxidant and free radical trapping activity that was first studied in isolated mitochondria.1 PGBx has anti-inflammatory and cytoprotective activity which may be attributed to inhibition of the 14 kDa sPLA2.2,3 At a dose of 1 mg/kg, PGBx significantly reduces the incidence of ulcers in rats.2
价 格:¥电议型 号:T35961产 地:中国大陆