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T71752Metoprolol fumarate;化合物 Metoprolol FumarateLopressor OROS|||CGP 2175C|||CGP 2175C ; Lopressor OROS;
Metoprolol fumarate (CGP 2175C) is a selectively active β1-adrenoceptor antagonist administered orally. It exhibits anti-inflammatory, antitumor, and anti-angiogenic properties.
价 格:¥电议型 号:T71752产 地:中国大陆
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T71199CGP7040;化合物 CGP7040CGP7040
CGP7040 is a rifamycin analogue, is a protein 50S ribosomal subunit inhibitor that was being developed by Novartis.
价 格:¥电议型 号:T71199产 地:中国大陆
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T71005CGP-42456A;化合物 CGP-42456ACGP-42456A
CGP-42456A - Benazepril Related Compound A, it is an Impurity. Benazepril is a prodrug which is metabolized by the liver into its active form benazeprilat via cleavage of the drug´s ester group. Benazepril and Benazeprilat inhibit angiotensin-converting enzyme (ACE) in human subjects and animals. Benazeprilat has much greater ACE inhibitory activity than does Benazepril. It is indicated for the treatment of hypertension.
价 格:¥电议型 号:T71005产 地:中国大陆
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T70566CGP 54062;化合物 CGP 54062CGP 54062
CGP 54062 is a GABA-B receptor antagonist; CGP 55845 is the (1S,2S)-isomer.
价 格:¥电议型 号:T70566产 地:中国大陆
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T70531CGP 55845;化合物 CGP 55845CGP 55845
CGP 55845 is a potent, selective GABAB receptor antagonist (IC50 = 5 nM) that prevents agonist binding (pKi = 8.35) and inhibits GABA and glutamate release (pEC50 values are 8.08 and 7.85 respectively).
价 格:¥电议型 号:T70531产 地:中国大陆
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T70521CGP-49823;化合物 CGP-49823CGP-49823
CGP-49823 is a non-peptide tachykinin NK1 receptor antagonist.
价 格:¥电议型 号:T70521产 地:中国大陆
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T70518CGP-53437;化合物 CGP-53437CGP-53437
CGP-53437 is a novel HIV-1 protease inhibitor, also potently inhibiting major aspartyl peptidase 1 (May1), a secreted Cryptococcus neoformans protease.
价 格:¥电议型 号:T70518产 地:中国大陆
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T70061CGP 71683 (free base);化合物 CGP 71683 (free base)CGP 71683 (free base)
CGP 71683 (free base) is a potent and highly selective non-peptide antagonist of the NPY Y(5) receptor in the study of obesity.
价 格:¥电议型 号:T70061产 地:中国大陆
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T69949CGP-78608;化合物 CGP-78608CGP-78608
CGP-78608 is a glycine site-specific N-methyl-D-aspartate receptor antagonist prevents activation of the NMDA/NO/CGMP pathway by ammonia.
价 格:¥电议型 号:T69949产 地:中国大陆
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T69891CGP 40215;化合物 CGP 40215CGP 40215
CGP 40215 is a specific S-adenosylmethionine decarboxylase (AdoMetDC) inhibitor that was found to inhibit the growth of Leishmania donovani promastigotes
价 格:¥电议型 号:T69891产 地:中国大陆
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T69200CGP74514A;化合物 CGP74514ACGP74514A
CGP74514A is a CDK1 inhibitor with potential anticancer activity. In U937 cells, CGP74514A - induced apoptosis (5 microM) became apparent within 4 hr and approached 100% by 24 hr. The pan- caspase inhibitor Boc-fmk and the caspase-8 inhibitor lETD-fmk opposed CGP74514A -induced caspase-9 activation and PARP degradation, but not cytochrome c or Smac/DIABLO release. CGP74514A -mediated apoptosis was substantially blocked by ectopic expression of full-length Bel- 2, a loop-deleted mutant Bcl-2, and
价 格:¥电议型 号:T69200产 地:中国大陆
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T68661Edatrexate;化合物 EdatrexateCGP 30694;CGP 30694
Edatrexate (CGP 30694), also known as 10-Ethyl-10-deazaaminopterin, is an analog of Methotrexate that demonstrates antitumor activity against Methotrexate-resistant tumors. This antifolate antimetabolite is utilized in research related to non-small-cell lung cancer, breast cancer, non-Hodgkin´s lymphoma, and head and neck cancer [1] [2].
价 格:¥电议型 号:T68661产 地:中国大陆
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T67442CGP-53716;化合物 CGP-53716CGP-53716
The growth factors, platelet-derived growth factor (PDGF) and basic fibroblast growth factor (bFGF) play major roles in enhanced smooth muscle cells growth in rodent blood vessels after vascular injury. Tyrosine kinase inhibition has been shown to be effective in blocking tyrosine phosphorylation at the PDGF and bFGF receptors in cultured fibroblast and vascular smooth muscle cells which in turn inhibits their proliferation[1]. CGP 53716 is a specific PDGFR tyrosine kinase inhibitor on SMC (smoo
价 格:¥电议型 号:T67442产 地:中国大陆
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T6720Vatalanib dihydrochloride;瓦他拉尼CGP-797870 dihydrochloride|||ZK-222584 dihydrochloride|||Vatalanib 2HC
Vatalanib dihydrochloride (PTK787 dihydrochloride)(IC50=37 nM) is an inhibitor of VEGFR2/KDR. It exhibits less effective against VEGFR1/Flt-1 and 18-fold against VEGFR3/Flt-4.
价 格:¥电议型 号:T6720产 地:中国大陆
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T6716Valsartan;缬沙坦Diovan|||Tareg|||CGP 48933;Diovan|||缬沙坦|||Tareg|||CGP 48933
Valsartan (CGP 48933) is a tetrazole derivative and angiotensin II type 1 receptor blocker that is used to treat hypertension.
价 格:¥电议型 号:T6716产 地:中国大陆
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T6680Staurosporine;星形孢菌素Antibiotic AM-2282|||AM-2282|||CGP 41251;Antibiotic AM-2282|||星形孢菌素|||AM-2282|||C
Staurosporine (AM-2282) is a protein kinase inhibitor with ATP-competitive and non-selective inhibitory activity (IC50=6/15/2/3/3000 nM) against PKC, PKA, c-Fgr, phosphorylase kinase and TAOK2. Staurosporine also induces apoptosis.
价 格:¥电议型 号:T6680产 地:中国大陆
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T6529Halobetasol propionate;卤倍他索丙酸酯Halobetasol Propionate|||Ulobetasol propionate|||BMY-30056|||CGP-1445
Halobetasol propionate (BMY-30056) is the propionate salt form of halobetasol, a synthetic corticosteroid with anti-inflammatory, antipruritic, and vasoconstrictor activities. Halobetasol, a topical steroid, diffuses across cell membranes to interact with cytoplasmic corticosteroid receptors located in both the dermal and intradermal cells, thereby activating gene expression of anti-inflammatory proteins mediated via corticosteroid receptor response element. Specifically, this agent induces phos
价 格:¥电议型 号:T6529产 地:中国大陆
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T6505Formoterol fumarate;福美特罗富马酸盐Formoterol Hemifumarate|||NSC 299587|||Eformoterol Hemifumarate|||CGP 25
Formoterol fumarate (Eformoterol Hemifumarate), an effective, specific and long-acting β2-adrenoceptor agonist, is utilized in the treatment of chronic obstructive pulmonary disease(COPD) and asthma.
价 格:¥电议型 号:T6505产 地:中国大陆
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T6470Diclofenac Potassium;双氯芬酸钾CGP-45840B|||Cataflam|||Voltfast;双氯芬酸钾|||CGP-45840B|||Cataflam|||Voltfast
Diclofenac Potassium (CGP-45840B) is a nonsteroidal anti-inflammatory drug taken to reduce inflammation and as an analgesic reducing pain in certain conditions.
价 格:¥电议型 号:T6470产 地:中国大陆
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T6440CGP 57380;化合物CGP 57380MNK1 Inhibitor;N3-(4-氟苯基)-1H-吡唑并[3,4-D]嘧啶-3,4-二胺|||MNK1 Inhibitor
CGP 57380 (MNK1 Inhibitor) is a potent MNK1 inhibitor with IC50 of 2.2 μM, exhibiting no inhibitory activity on p38, JNK1, ERK1 and -2, PKC, or c-Src-like kinases.
价 格:¥电议型 号:T6440产 地:中国大陆