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T67428mDPR-Val-Cit-PAB-MMAE;化合物 mDPR-Val-Cit-PAB-MMAEmDPR-Val-Cit-PAB-MMAE
mDPR-Val-Cit-PAB-MMAE consists the ADCs linker (mDPR-Val-Cit-PAB) and potent tubulin inhibitor (MMAE), mDPR-Val-Cit-PAB-MMAE is an antibody drug conjugate.
价 格:¥电议型 号:T67428产 地:中国大陆
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T6651LSafinamide;沙芬酰胺EMD1195686|||FCE26743|||FCE 26743|||EMD-1195686|||EMD 1195686|||FCE-26743;EMD1195686|
Safinamide (FCE-26743) is a reversible and selective monoamine oxidase B (IC50 0.098μM) inhibitor, reducing the degradation of dopamine, and a glutamate release inhibitor (IC50 8μM). It also inhibits dopamine reuptake. Safinamide also blocks sodium and calcium channels. Potential additional uses of Safinamide might be Parkinson´s disease, restless leg syndrome and epilepsy.
价 格:¥电议型 号:T6651L产 地:中国大陆
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T6651Safinamide mesylate;沙芬酰胺甲磺酸盐PNU-151774E,FCE28073|||PNU-151774E|||NW-1015|||EMD 1195686 mesylate;PNU-
Safinamide mesylate (EMD 1195686 mesylate) , a mesylate salt of Safinamide, can reversibly and specifically inhibit MAO-B (IC50: 98 nM), has 5918-fold selectivity against MAO-A.
价 格:¥电议型 号:T6651产 地:中国大陆
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T6635EMD638683;化合物EMD638683EMD638683
EMD638683,a novel SGK inhibitor with antihypertensive potency(with an IC50 of 3 μM).
价 格:¥电议型 号:T6635产 地:中国大陆
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T62839Dalzanemdor;化合物DalzanemdorSAGE-718;SAGE-718
Dalzanemdor (SAGE-718) is an NMDA receptor-positive modulator of metabolism that can be used to study Huntington´s chorea, Alzheimer´s disease, and cognitive dysfunction.
价 格:¥电议型 号:T62839产 地:中国大陆
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T62670Cemdomespib;化合物 CemdomespibCemdomespib
Cemdomespib (KU-596) is a potent second-generation Hsp90 modulator. cemdomespib induces a heat shock response, induces Hsp70 levels and has neuroprotective effects. cemdomespib has been shown to improve sensory deficits in models of diabetic peripheral neuropathy.
价 格:¥电议型 号:T62670产 地:中国大陆
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T6232Vilazodone Hydrochloride;盐酸维拉佐酮SB659746A|||EMD 68843|||Vilazodone HCl;盐酸维拉佐酮|||SB659746A|||EMD 68843
Vilazodone Hydrochloride (EMD 68843) , a partial agonist of 5-HT1A receptors and specific serotonin reuptake inhibitor (SSRI), is utilized in treating of the major depressive disorder.
价 格:¥电议型 号:T6232产 地:中国大陆
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T6121Tepotinib;特泊替尼EMD-1214063|||MSC2156119;特泊替尼|||EMD-1214063|||MSC2156119
Tepotinib (EMD-1214063) is an inhibitor of MET tyrosine kinase with potential antineoplastic activity.
价 格:¥电议型 号:T6121产 地:中国大陆
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T5333Rimeporide hydrochloride;盐酸RimeporideEMD-87580 hydrochloride;盐酸Rimeporide|||EMD-87580 hydrochloride
Rimeporide hydrochloride (EMD-87580 hydrochloride) is a potent and selective Sodium hydrogen exchange 1 (NHE-1) inhibitor.
价 格:¥电议型 号:T5333产 地:中国大陆
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T5319Rimeporide;化合物RimeporideEMD-87580;EMD-87580
Rimeporide (EMD-87580) (EMD-87580) is a potent and selective Sodium hydrogen exchange 1 (NHE-1) inhibitor.
价 格:¥电议型 号:T5319产 地:中国大陆
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T4691Asimadoline hydrochloride;阿西马朵林盐酸盐EMD-61753 hydrochloride;EMD-61753 hydrochloride|||阿西马朵林盐酸盐
Asimadoline hydrochloride (EMD-61753 hydrochloride) is a κ-opioid receptor agonist potentially for the treatment of pruritus. Asimadoline hydrochloride has also been shown to be used in the treatment of irritable bowel syndrome.
价 格:¥电议型 号:T4691产 地:中国大陆
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T4633Asimadoline阿西马朵林EMD-61753|||阿西马朵林
Asimadoline (EMD-61753) is a proprietary small molecule therapeutic, originally discovered by Merck KGaA of Darmstadt, Germany. Asimadoline was originally developed to treat peripheral pain such as arthritis. Asimadoline is an orally administered agent that acts as a kappa opioid receptor agonist. It has shown encouraging clinical efficacy for the treatment of IBS in a barostat study in IBS patients and has the potential for treating other gastrointestinal diseases.
价 格:¥电议型 号:T4633产 地:中国大陆
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T41150EMD 527040 hydrochloride;EMD 527040 hydrochlorideEMD 527040 hydrochloride
EMD 527040 hydrochloride is an effective integrin αVβ6 inhibitor. The IC 50 values of EMD 527040 hydrochloride were 6 nM and 1.6 μM to inhibit αVβ6 binding to fibronectin and αVβ6 expression cells to fibronectin, respectively. EMD 527040 hydrochloride shows antifibrotic activity in animal models of biliary fibrosis and is active in vivo.
价 格:¥电议型 号:T41150产 地:中国大陆
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T41058Nelonemdaz potassiumNelonemdaz potassiumNeu2000potassium|||Salfaprodil
Nelonemdaz potassium (also known as Salfaprodil) is a potent NR2B-selective and uncompetitive antagonist of N-methyl-D-aspartate (NMDA). This compound exhibits remarkable neuroprotection against cell death induced by both NMDA and free radicals, in addition to its role as a free radical scavenger.
价 格:¥电议型 号:T41058产 地:中国大陆
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T40973MDNI-caged-L-glutamate;MDNI-caged-L-glutamateMDNI-caged-L-glutamate|||MDNI-glu;MDNI-caged-L-glutamat
MDNI-glu is a photosensitive derivative of L-glutamate, a major excitatory amino acid, that is biologically inert. It demonstrates improved utilization of incident light.
价 格:¥电议型 号:T40973产 地:中国大陆
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T40943EMD527040;EMD527040EMD527040
EMD527040 is a powerful and highly specific αvβ6 antagonist, exhibiting notable antifibrotic properties. It is suitable for conducting research on carcinoma and liver fibrosis.
价 格:¥电议型 号:T40943产 地:中国大陆
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T40439SarizotanSarizotanEMD 128130
Sarizotan (EMD 128130) is an orally active compound that acts as an agonist for serotonin 5-HT 1A receptors and dopamine receptors. It has shown potent activity with IC 50 values of 6.5 nM for rat 5-HT 1A , 0.1 nM for human 5-HT 1A , 15.1 nM for rat D 2 , 17 nM for human D 2 , 6.8 nM for human D 3 , and 2.4 nM for human D 4.2 .
价 格:¥电议型 号:T40439产 地:中国大陆
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T39940Plazinemdor;PlazinemdorPlazinemdor
Plazinemdor is an NMDA receptor positive allosteric modulator with potential applications in psychiatric, neurological, neurodevelopmental disorders, and diseases of the nervous system.
价 格:¥电议型 号:T39940产 地:中国大陆
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T39335Anti-virus agent 1Anti-virus agent 1Anti-virus agent 1|||Remdesivir isopropyl ester analog
Anti-virus agent 1 (compound 4i), a phosphoramidate prodrug of GS-5734, exhibits potent antiviral efficacy. It is primarily utilized in the study of coronavirus and Ebola virus (EBOV).
价 格:¥电议型 号:T39335产 地:中国大陆
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T39334Remdesivir nucleoside monophosphate;Remdesivir nucleoside monophosphateRemdesivir nucleoside monopho
Remdesivir nucleoside monophosphate, a metabolite of Remdesivir, is a potent antiviral compound with nucleoside analogue characteristics. It exhibits effective antiviral activity against both SARS-CoV and MERS-CoV.
价 格:¥电议型 号:T39334产 地:中国大陆