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产品数:86101
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已选条件
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TQ0255OlafertinibInhibitor,ErbB-1,Olafertinib,Epidermal growth factor receptor,NSCLC,HER1,EGFR,inhibit
CK-101 (RX-518) is a novel mutant-selective, irreversible, orally available EGFR inhibitor. It can overcome T790M-mediated resistance in NSCLC.
价 格:¥电议型 号:TQ0255产 地:中国大陆
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T6496Vactosertibantimetastatic,invasion,Smad,TEW7197,Transforming growth factor beta receptors,TGFβ,migra
Vactosertib is an orally bioavailable inhibitor of the serine/threonine kinase, transforming growth factor (TGF)-beta receptor type 1 (TGFBR1), also known as activin receptor-like kinase 5 (ALK5), with potential antineoplastic activity.
价 格:¥电议型 号:T6496产 地:中国大陆
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T6S0627Mesaconitineinhibit,Mesaconitine,Inhibitor,Tumor Necrosis Factor Receptor,TNFR,TNF Receptor
1. Mesaconitine has antiinflammatory activity. 2. Mesaconitine has antinociceptive activity through cyclic AMP and stimulation of the central β-adrenergic system.
价 格:¥电议型 号:T6S0627产 地:中国大陆
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T6153IcotinibIcotinib,Inhibitor,BPI2009,BPI 2009,ErbB-1,HER1,inhibit,EGFR,Epidermal growth factor recepto
Icotinib is an orally available quinazoline-based inhibitor of epidermal growth factor receptor (EGFR), with potential antineoplastic activity.
价 格:¥电议型 号:T6153产 地:中国大陆
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T6429Caffeic Acid Phenethyl EsterApoptosis,Caffeic Acid Phenethyl Ester,Nuclear factor-kappaB,Inhibitor,N
Caffeic Acid Phenethyl Ester (CAPE) inhibits the activation of nuclear transcription factor NF-kappa B and may suppress p70S6K and Akt-driven signaling pathways, with antineoplastic, cytoprotective and immunomodulating activities. CAPE is the phenethyl alcohol ester of caffeic acid and a bioactive component of honeybee hive propolis. In addition, CAPE inhibits PDGF-induced proliferation of vascular smooth muscle cells through the activation of p38 mitogen-activated protein kinase (MAPK) and hypo
价 格:¥电议型 号:T6429产 地:中国大陆
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T8151MobocertinibAP-32788,Epidermal growth factor receptor,TAK-788,H1975,Inhibitor,Mobocertinib,HCC827,in
Mobocertinib is a potent inhibitor of epidermal growth factor receptor (EGFR) and an antineoplastic agent
价 格:¥电议型 号:T8151产 地:中国大陆
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T4341BetrixabanBetrixaban,PRT-054021,Factor Xa,inhibit,Fxa,PRT 054021,Inhibitor
Betrixaban is a non-vitamin K oral anticoagulant whose action is driven by the competitive and reversible inhibition of the factor Xa [1]. It was selected among all lead compounds due to its low hERG channel affinity while sustaining its factor Xa inhibition capacity [3]. Betrixaban, now developed by Portola Pharmaceuticals Inc., is prescribed as a venous thromboembolism (VTE) prophylactic for adult patients with moderate to severe restricted motility or with other risks for VTE [2]. VTE can be
价 格:¥电议型 号:T4341产 地:中国大陆
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T828814-Deoxyandrographolideplatelet activating factor,rat,bovine neutrophils,14 Deoxyandrographolide,Cal
14-Deoxyandrographolide is a bioactive compound of Andrographis paniculata with hepatoprotective efficacy. It desensitizes hepatocytes to TNF-α-mediated apoptosis through the release of TNFRSF1A release.
价 格:¥电议型 号:T8288产 地:中国大陆
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T22667CID 5951923Krüppel-like factor,CID-5951923,CID5951923,KLF5,inhibit,cancer,factor,KLF,transcription,I
CID 5951923 is an inhibitor of KLF5 transcription factor with an IC50 of 603 nM.
价 格:¥电议型 号:T22667产 地:中国大陆
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T7802M1001786-O,HIF/HIF Prolyl-Hydroxylase,inhibit,HIF-PH,M-1001,Hypoxia-inducible factors,HIFs,chronic k
M1001 is a HIF-2α agonist.
价 格:¥电议型 号:T7802产 地:中国大陆
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T9912TrastuzumabEGFR,Trastuzumab,Anti-Human HER2, Humanized Antibody,Epidermal growth factor receptor,HER
Trastuzumab is a humanized monoclonal antibody for patients with invasive breast cancers that overexpress HER2. Trastuzumab has been clinically used to treat HER2 Positive Metastatic Breast Cancer and HER2 Positive Gastric Cancer.
价 格:¥电议型 号:T9912产 地:中国大陆
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T7001TIC10TIC 10,Tumor Necrosis Factor Receptor,inhibit,ONC201,Inhibitor,TNF Receptor,Apoptosis,TNFR,ONC
TIC10 inactivates Akt and ERK to induce TRAIL through Foxo3a, possesses superior drug properties: delivery across the blood-brain barrier, superior stability and improved pharmacokinetics. Phase 1/2.
价 格:¥电议型 号:T7001产 地:中国大陆
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T4485LazertinibErbB-1,YH 25448,GNS1480,Lazertinib,EGFR,Inhibitor,YH-25448,Epidermal growth factor recepto
Lazertinib is an effective, highly mutant-selective and irreversible EGFR-TKI with IC50 values of 1.7 nM, 2 nM, 5 nM, 20.6 nM and 76 nM for Del19/T790M, L858R/T790M, Del19, L85R and Wild type EGFR respectively.
价 格:¥电议型 号:T4485产 地:中国大陆
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T6427ButeinPDE4,Epidermal growth factor receptor,Inhibitor,EGFR,MAPK,ErbB-1,Apoptosis,Autophagy,FoxO3a,in
Butein, a plant polyphenol, is isolated from Rhus verniciflua. It can inhibit the activation of protein tyrosine kinase, NF-κB and STAT3, and also can inhibit EGFR.
价 格:¥电议型 号:T6427产 地:中国大陆
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T8846beta-Escinproliferation,anti-angiogenic,β-Escin,fibroblast growth factor,betaEscin,CAM angiogenesis,
beta-Escin is a natural mixture of triterpenoid saponins isolated from horse chestnut (Aesculus hippocastanum) seeds, can be used as a vasoprotective anti-inflammatory, anti-edematous and anti-nociceptive agent.
价 格:¥电议型 号:T8846产 地:中国大陆
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T6710Troxipidefactor,Inhibitor,gastritis,Troxipide,inhibit,orally,defensive,ulcer,antiulcer,gastric
Troxipide, a new-type systemic non-antisecretory gastric cytoprotective agent, which is mucus-secreting, anti-ulcer, and anti-inflammatory properties irrespective of pH of stomach or duodenum.
价 格:¥电议型 号:T6710产 地:中国大陆
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T9052XL092Axl,c-Met/HGFR,Vascular endothelial growth factor receptor,p-MET,XL092,TAM Receptor,p-VEGFR2,Me
JUN04542 is an Axl Mer cMet KDR inhibitor for the treatment of Axl and Mer receptor tyrosine kinase- dependent disorders.
价 格:¥电议型 号:T9052产 地:中国大陆
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TN1712GossypinAntiinflammatory,inhibit,Nuclear factor-κB,Gossypin,Inhibitor,Antioxidant,Anticancer,cardiov
Gossypin has antidiabetic, antioxdiant, anticonvulsant, anti-allergic, antiinflammatory, antinociceptive, cytotoxic and antibacterial activities; it inhibits the NF-kappaB activation pathway, which may explain its role in the suppression of inflammation, carcinogenesis, and angiogenesis.
价 格:¥电议型 号:TN1712产 地:中国大陆
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TQ0021NingetinibVascular endothelial growth factor receptor,inhibit,c-Met/HGFR,TAM Receptor,Mer,Tyro3,VEGF
Ningetinib (CT053PTSA) is an orally bioavailable tyrosine kinase inhibitor with IC50s of <1.0, 1.9 and 6.7 nM for Axl, VEGFR2, and c-Met, respectively.
价 格:¥电议型 号:TQ0021产 地:中国大陆
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T6894ML264ML-264,Inhibitor,Krüppel-like factor,ML 264,inhibit,ML264,KLF
ML264 is a selective kruppel-like factor 5 (KLF5) inhibitor, which potently Inhibits growth of Colorectal Cancer.
价 格:¥电议型 号:T6894产 地:中国大陆