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T78212RMC-9805;化合物 RMC-9805KRAS G12D inhibitor 18|||KRAS G12D IN 18;KRAS G12D inhibitor 18|||KRAS G12D IN
RMC-9805 is a potent KRAS G12D inhibitor with potential anti-tumor and inhibitory activity against tumor cell proliferation for the study of pancreatic cancer.
价 格:¥电议型 号:T78212产 地:中国大陆
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T78170Kras4B G12D-IN-1;Kras4B G12D 抑制剂 1Kras4B G12D-IN-1
Kras4B G12D-IN-1 is an anticancer agent that functions as an inhibitor of the Kras4B G12D protein. It effectively reduces the expression of Kras protein in mouse embryonic fibroblasts (MEFs) harboring the Kras4B G12D mutation[1].
价 格:¥电议型 号:T78170产 地:中国大陆
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T77926PROTAC KRAS G12C degrader-1;化合物 PROTAC KRAS G12C degrader-1PROTAC KRAS G12C degrader-1
PROTAC KRAS G12C degrader-1, a cereblon-based degrader, promotes CRBN/KRAS G12C dimerization and facilitates the degradation of GFP-KRAS G12C in reporter cells [1].
价 格:¥电议型 号:T77926产 地:中国大陆
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T77805KRAS G12C mutant protein inhibitor A-1;化合物 KRAS G12C mutant protein inhibitor A-1KRAS G12C mutant pr
KRAS G12C mutant protein inhibitor A-1 can be used in studies about Ras.
价 格:¥电议型 号:T77805产 地:中国大陆
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T77804KRAS G12D mutation regulator 4;化合物 KRAS G12D mutation regulator 4KRAS G12D mutation regulator 4
KRAS G12D mutation regulator 4 can be used in studies about Ras.
价 格:¥电议型 号:T77804产 地:中国大陆
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T77802KRAS G12C inhibitor 1R;化合物 KRAS G12C inhibitor 1RKRAS G12C inhibitor 1R
KRAS G12C inhibitor 1R can be used in studies about Ras.
价 格:¥电议型 号:T77802产 地:中国大陆
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T75119KRASG12Cu00A0IN-2;化合物 KRASG12Cu00A0IN-2KRASG12Cu00A0IN-2
KRASG12C IN-2 (compound 17) is an orally active inhibitor of KRAS G12C, which effectively suppresses tumor growth in mice [1].
价 格:¥电议型 号:T75119产 地:中国大陆
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T74973KRas G12R inhibitor 1;化合物 KRas G12R inhibitor 1KRas G12R inhibitor 1
KRas G12R Inhibitor 1 (compound 3) is a selective covalent inhibitor targeting the KRas G12R mutation, leveraging the high nucleophilicity of mutant cysteines to bind irreversibly within the K-Ras Switch II region. This compound is utilized in cancer research [1].
价 格:¥电议型 号:T74973产 地:中国大陆
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T74920G12Si-2;化合物 G12Si-2G12Si-2
G12Si-2, an analog of G12Si-1 , is a negative control tool. G12Si-2 is not a covalent inhibitor of the G12S mutant of K-Ras [1] .
价 格:¥电议型 号:T74920产 地:中国大陆
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T74663KRAS G12D inhibitor 17;化合物 KRAS G12D inhibitor 17KRAS G12D inhibitor 17
KRAS G12D Inhibitor 17 (example 8), a quinazoline-linked (4R)-4-hydroxy-L-prolinamide compound, acts as a proteolysis targeting chimera (PROTAC) [1], specifically inducing degradation of the G12D-mutation KRAS protein.
价 格:¥电议型 号:T74663产 地:中国大陆
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T74607KRAS G12D inhibitor 15;化合物 KRAS G12D inhibitor 15KRAS G12D inhibitor 15
KRAS G12D inhibitor 15 is a potent inhibitor specifically targeting the KRAS G12D mutation. It holds potential for research into numerous diseases or disorders, including cancer and its metastases[1].
价 格:¥电议型 号:T74607产 地:中国大陆
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T73828KRAS G12D inhibitor 3 TFA;化合物 KRAS G12D inhibitor 3 TFAKRAS G12D inhibitor 3 TFA
KRAS G12D Inhibitor 3 TFA, exhibiting an inhibitory concentration (IC50) of less than 500 nM, is effective as an antitumor agent.
价 格:¥电议型 号:T73828产 地:中国大陆
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T72394KRAS G12D inhibitor 3;化合物 KRAS G12D inhibitor 3KRAS G12D inhibitor 3
KRAS G12D Inhibitor 3, a compound targeting the KRAS G12D mutation, demonstrates potent antitumor efficacy with an inhibitory concentration (IC50) of less than 500 nM.
价 格:¥电议型 号:T72394产 地:中国大陆
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T72356KRAS G12C inhibitor 56;化合物 KRAS G12C inhibitor 56KRAS G12C inhibitor 56
KRAS G12C inhibitor 56, a powerful inhibitor of SOS1 with an inhibitory concentration (IC50) of 1.6 nM, holds promise for use in cancer research.
价 格:¥电议型 号:T72356产 地:中国大陆
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T72355KRAS G12D inhibitor 16;化合物 KRAS G12D inhibitor 16KRAS G12D inhibitor 16
KRAS G12D Inhibitor 16 is a potent compound targeting the KRAS G12D and its mutation, exhibiting inhibitory activity with IC50 values of 0.7 nM and 0.35 μM, respectively. It is utilized in researching various malignant tumors including pancreatic ductal adenocarcinomas (PDAC), colon and rectal carcinomas (CRC), and non-small cell lung carcinomas (NSCLC).
价 格:¥电议型 号:T72355产 地:中国大陆
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T72348KRAS G12C inhibitor 48;化合物 KRAS G12C inhibitor 48KRAS G12C inhibitor 48
KRAS G12C Inhibitor 48 is a potent inhibitor targeting the KRAS G12C mutation, exhibiting an IC50 value of 639.91 nM. Demonstrating antiproliferative activity, KRAS G12C Inhibitor 48 (0-50 ?M) yields IC50 values of 0.796 ?M, 6.33 ?M, and 16.14 ?M against H358, H23, and A549 cell lines, respectively.
价 格:¥电议型 号:T72348产 地:中国大陆
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T72346KRAS G12C inhibitor 20;化合物 KRAS G12C inhibitor 20KRAS G12C inhibitor 20
KRAS G12C inhibitor 20 is a KRAS G12C inhibitor.
价 格:¥电议型 号:T72346产 地:中国大陆
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T72345KRAS G12D inhibitor 10;化合物 KRAS G12D inhibitor 10KRAS G12D inhibitor 10
KRAS G12D Inhibitor 10 is a potent agent targeting the KRAS G12D mutation, a variant in the Ras protein family crucial for cellular growth and development. This compound shows promise for investigating cancers mediated by KRAS G12D.
价 格:¥电议型 号:T72345产 地:中国大陆
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T72344KRAS G12C inhibitor 41;化合物 KRAS G12C inhibitor 41KRAS G12C inhibitor 41
KRAS G12C Inhibitor 41 is a potent agent targeting the KRAS G12C mutation within the Ras family of proteins, which are crucial for intracellular signaling related to growth and development. This compound holds significant potential for advancing research in cancers mediated by KRAS G12C.
价 格:¥电议型 号:T72344产 地:中国大陆
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T72343KRAS G12C inhibitor 40;化合物 KRAS G12C inhibitor 40KRAS G12C inhibitor 40
KRAS G12C inhibitor 40, a potent suppressor of the KRAS G12C, targets the Ras family of intracellular signaling proteins crucial for growth and development. This compound holds significant potential for researching cancers mediated by KRAS G12C.
价 格:¥电议型 号:T72343产 地:中国大陆