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T64114SPH5030;化合物 SPH5030SPH5030
SPH5030 is an irreversible, selective inhibitor of HER2. SPH5030 inhibits HER2WT (IC50: 3.51 nM), EGFRWT (IC50: 8.13 nM). SPH5030 can be used in cancer research.
价 格:¥电议型 号:T64114产 地:中国大陆
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T63777QH536;化合物 QH536QH536
QH536 is an effective degrader of HMGCR (EC50: 0.22 μM).QH536 exhibits anti-inflammatory effects and does not have the side effect of inducing intracellular accumulation of cholesterol.QH536 can be used to study cardiovascular disease and non-alcoholic steatohepatitis.
价 格:¥电议型 号:T63777产 地:中国大陆
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T63563AN-12-H5;化合物 AN-12-H5AN-12-H5
AN-12-H5 is an anti-enteroviral compound that targets the replication process of PV and EV71 viruses.
价 格:¥电议型 号:T63563产 地:中国大陆
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T60984TH588 hydrochloride;化合物 TH588 hydrochlorideTH588 hydrochloride
TH588 hydrochloride is first-in-class inhibitor of nudix hydrolase family that selectively and effectively bind and inhibit the MTH1 with IC50 value of 5 nM.
价 格:¥电议型 号:T60984产 地:中国大陆
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T6024Zoligratinib;化合物CH5183284FF284|||CH5183284|||Debio 1347;FF284|||CH5183284|||Debio 1347
Zoligratinib (CH5183284) is a selective and orally available FGFR inhibitor, which is for FGFR1(IC50=9.3 nM), FGFR2(IC50=7.6 nM), FGFR3(IC50=290), and FGFR4(IC50=22 nM), respectively.
价 格:¥电议型 号:T6024产 地:中国大陆
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T39785LTH5427;化合物TH5427TH5427
TH5427 is a lead NUDT5 inhibitor(MG assay IC50?=?29?nM).
价 格:¥电议型 号:T39785L产 地:中国大陆
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T39785TH5427 hydrochlorideTH5427 hydrochlorideTH5427 hydrochloride|||TH-5427 hydrochloride
TH5427 hydrochloride is a potent and selective inhibitor of NUDT5 with an IC50 of 29 nM. It demonstrates a remarkable 690-fold selectivity towards NUDT5 compared to MTH1. Moreover, TH5427 hydrochloride effectively inhibits progestin-dependent, PAR-derived nuclear ATP synthesis in breast cancer cells, thereby impeding chromatin remodeling, gene regulation, and ultimately suppressing proliferation.
价 格:¥电议型 号:T39785产 地:中国大陆
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T37042SCH529074;化合物SCH529074SCH 529074;SCH 529074
SCH529074 is a selective activator of p53 (Ki = 1 μM) and can be used in studies about non-small-cell lung carcinoma. SCH529074 restores mutant p53 function and interrupts HDM2-mediated ubiquitination of wild Type p53.
价 格:¥电议型 号:T37042产 地:中国大陆
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T35050Vesamicol hydrochloride;化合物 T35050AH 5183 hydrochloride|||AH5183 hydrochloride|||AH-5183 hydrochlori
Vesamicol hydrochloride is a biochemical.
价 格:¥电议型 号:T35050产 地:中国大陆
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T34632SH-5;化合物 T34632SH5 PIA5. LchiroInositol 1deoxy6Omethyl 5(2R)2methoxy3(octadecyloxy)propyl hydrogen p
SH-5, an AKT inhibitor potentiates apoptosis and inhibits invasion through the suppression of anti-apoptotic, proliferative and metastatic gene products regulated by IκBα kinase activation.
价 格:¥电议型 号:T34632产 地:中国大陆
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T34571SCH 54388;化合物 T34571W 873|||SCH54388|||W-873|||SCH-54388|||BRN 3051738;W 873|||SCH54388|||W-873|||SC
SCH 54388 is a biochemical.
价 格:¥电议型 号:T34571产 地:中国大陆
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T31055CP-457493;化合物 T31055OSI-493|||Erlotinib metabolite M6|||CP457493|||UNII-X0JH558S7E;OSI-493|||Erlotin
CP-457493 is a bio-active chemical.
价 格:¥电议型 号:T31055产 地:中国大陆
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T30868CH-5137291;化合物 T30868CH 5137291|||CH5137291;CH 5137291|||CH5137291
CH-5137291 is a pure AR antagonist with AR nuclear translocation inhibition activity. It suppresses castration and prevents the growth of prostate cancer cells.
价 格:¥电议型 号:T30868产 地:中国大陆
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T28778Silperisone HCl;西哌立松盐酸盐RGH5002|||SILA336|||RGH-5002|||Silperisone hydrochloride|||SILA-336;RGH5002||
Silperisone HCl (RGH-5002) blocks sodium and calcium channels in cells, decreases excitability and contractility of muscle cells, reduces peripheral tone, and acts as a muscle relaxant and peripheral vasodilator. Silperisone HCl is used to treat recurrent painful myoclonus due to spinal cord injury, abnormal hypertonia due to cerebrovascular disease, dystonia symptoms, cone tension syndrome, multiple sclerosis myospasm and myelitis. silperisone is a sodium channel protein type 2 alpha channel bl
价 格:¥电议型 号:T28778产 地:中国大陆
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T28730SCH51048;化合物 T28730SCH 51048|||SCH-51048;SCH 51048|||SCH-51048
SCH 51048 is a broad spectrum antifungal with oral activity.
价 格:¥电议型 号:T28730产 地:中国大陆
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T28729SCH-50910 free base;化合物 T28729SCH50910|||SCH 50910;SCH50910|||SCH 50910
SCH-50910 is an antagonist of GABAB receptor.
价 格:¥电议型 号:T28729产 地:中国大陆
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T28722SCH 57790;化合物SCH 57790SCH57790|||SCH-57790;SCH57790|||SCH-57790
SCH 57790 is a novel and selective muscarinic M(2) receptor antagonist that releases acetylcholine and enhances cognition in experimental animals for the treatment of Alzheimer´s disease.
价 格:¥电议型 号:T28722产 地:中国大陆
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T2619CH5132799;化合物CH5132799CH5132799
CH5132799 has been used in trials studying the treatment of Solid Tumors.
价 格:¥电议型 号:T2619产 地:中国大陆
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T25234CH5447240;化合物 T25234CH 5447240|||CH-5447240;CH 5447240|||CH-5447240
CH5447240 is an effective Human Parathyroid Hormone Receptor 1 (hPTHR1) Agonist for the treatment of Hypoparathyroidism. CH5447240 showed a potent in vitro hPTHR1 agonist effect (EC20: 3.0 nM; EC50: 12 nM). It showed 55% oral bioavailability and a significantly elevated serum calcium level in hypocalcemic model rats.
价 格:¥电议型 号:T25234产 地:中国大陆
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T24934Vesamicol;化合物 T24934AH-5183|||AH 5183|||AH5183;AH-5183|||AH 5183|||AH5183
Vesamicol is an experimental drug. It acting presynaptically by inhibiting acetylcholine uptake into synaptic vesicles and reducing its release.
价 格:¥电议型 号:T24934产 地:中国大陆