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  • T2327PelitinibPelitinib,WAY-EKB 569,EKB-569

    Pelitinib (EKB-569) is an effective irreversible EGFR inhibitor (IC50: 38.5 nM).

    价 格:¥电议型 号:T2327产 地:美洲

  • T5093Pim1/AKK1-IN-1Pim1/AKK1-IN-1,LKB1/AAK1 dual inhibitor,MDK-2275

    Pim1/AKK1-IN-1 is a potent multi-kinase inhibitor with Kd values of 35 nM/53 nM/75 nM/380 nM for Pim1/AKK1/MST2/LKB1 respectively, and also inhibits MPSK1 and TNIK.

    价 格:¥电议型 号:T5093产 地:美洲

  • T5360EprotiromeEprotirome,KB2115,

    Eprotirome, a synthetic thyroid hormone mimetic, is a thyroid hormone receptor agonist.

    价 格:¥电议型 号:T5360产 地:美洲

  • T5S1569AKBAAKBA,Acetyl-11-keto-β-boswellic acid,3-O-Acetyl-11-keto-β-boswellic acid

    1. 3-O-Acetyl-11-keto-beta-boswellic acid inhibits 5-lipoxygenase product formation with an IC(5) of 1.5 m muM.

    价 格:¥电议型 号:T5S1569产 地:美洲

  • T6144KB-R7943KB-R7943,KB-R7943 mesylate,

    KB-R7943 mesylate is a widely used inhibitor of the reverse Na+/Ca2+ exchanger (NCXrev) with IC50 of 5.7±2.1 μM.

    价 格:¥电议型 号:T6144产 地:美洲

  • T6484EI1EI1,Ezh2 inhibitor,KB-145943

    EI1 is a potent and selective EZH2 inhibitor with IC50 of 15 nM and 13 nM for EZH2 (WT) and EZH2 (Y641F), respectively.

    价 格:¥电议型 号:T6484产 地:美洲

  • T6571Lomerizine hydrochlorideLomerizine hydrochloride,KB-2796,Lomerizine dihydrochloride

    Lomerizine dihydrochloride is an antagonist of L- and T-type voltage-gated calcium channels used to treat migraine.

    价 格:¥电议型 号:T6571产 地:美洲

  • T80914Tyr0-Neurokinin B;化合物 Tyr0-Neurokinin BTyr-NKB;Tyr-NKB

    Tyr0-Neurokinin B (Tyr-NKB), an analogue of Neurokinin B, induces contractions in the bladder [1].

    价 格:¥电议型 号:T80914产 地:中国大陆

  • T80731Zifanocycline TFA;化合物 Zifanocycline TFAKBP-7072 TFA;KBP-7072 TFA

    Zifanocycline (KBP-7072) TFA is a semi-synthetic aminomethylcycline antibiotic with oral bioavailability, targeting bacterial ribosomes to impede their function. Displaying a broad spectrum of in vitro antimicrobial efficacy, it combats both Gram-positive and Gram-negative bacteria, inclusive of numerous multidrug-resistant strains. Its clinical investigations focus on efficacies in treating acute bacterial skin and skin structure infections, community-acquired bacterial pneumonia, and complicat

    价 格:¥电议型 号:T80731产 地:中国大陆

  • T80195Garvicin KS, GakB;化合物 Garvicin KS, GakBGarvicin KS, GakB

    Garvicin KS (GarKS) is a bacteriocin comprising a 34-amino-acid peptide, GakB, along with two additional peptides, GakA and GakC. GakB specifically impairs fibroblast viability and proliferation. When combined with GakA, GarKS demonstrates enhanced peptide stability, antimicrobial activity, and notable impacts on fibroblast viability and proliferation. Regarding methicillin-sensitive Staphylococcus aureus (MSSA) inhibition, minimum inhibitory concentration (MIC) values rank the peptides in desce

    价 格:¥电议型 号:T80195产 地:中国大陆

  • T79184FKBP51F67V-selective antagonist Ligand2;化合物 FKBP51F67V-selective antagonist Ligand2FKBP51F67V-select

    FKBP51F67V-selective antagonist Ligand2 (example 3-3), a potent ligand, selectively binds to the FKBP51 F67V variant, with no affinity for wild-type FKBP51 or FKBP52 [1]. It effectively reverses the anxiogenic phenotype resulting from FKBP51 F67V overexpression in the amygdala.

    价 格:¥电议型 号:T79184产 地:中国大陆

  • T79156(R)-SKBG-1;化合物 (R)-SKBG-1(R)-SKBG-1

    (R)-SKBG-1 is an inhibitor of the RNA-binding protein NONO, effectively downregulating androgen receptor expression by targeting both AR-FL mRNA and AR-V7 mRNA, with inhibition concentration (IC50) values of 3.1 μM and 5.5 μM, respectively [1].

    价 格:¥电议型 号:T79156产 地:中国大陆

  • T79011TrkB-IN-1;化合物 TrkB-IN-1TrkB-IN-1

    TrkB-IN-1 is a potent, orally active agonist of the TrkB receptor, with favorable pharmacokinetic (PK) properties. It has been shown to reverse cognitive deficits in an Alzheimer´s disease (AD) mouse model, thus serving as a valuable tool for Alzheimer’s disease research [1].

    价 格:¥电议型 号:T79011产 地:中国大陆

  • T78313Fazpilodemab;化合物 FazpilodemabBFKB8488A;BFKB8488A

    Fazpilodemab (BFKB8488A) is a humanized agonistic bispecific antibody that targets fibroblast growth factor receptor 1c (FGFR1c) and Klothoβ. It is utilized in research pertaining to Type 2 diabetes mellitus (T2DM) and nonalcoholic fatty liver disease (NAFLD) [1].

    价 格:¥电议型 号:T78313产 地:中国大陆

  • T71840FKBP12-IN-Q2;化合物 FKBP12-IN-Q2FKBP12-IN-Q2

    FKBP12-IN-Q2 is an inhibitor of FKBP12.

    价 格:¥电议型 号:T71840产 地:中国大陆

  • T70382KBP-7018 HCl;化合物 KBP-7018 HClKBP-7018 HCl

    KBP-7018 Hydrochloride is a novel, tyrosine kinase-selective inhibitor with potent effects on three fibrotic kinases (c-KIT, PDGFR, and RET).

    价 格:¥电议型 号:T70382产 地:中国大陆

  • T70280KB-R7785;化合物 KB-R7785KB-R7785

    KB-R7785 is a novel ADAM12 and MMP inhibitor, ameliorating cardiac function in a transverse aortic constriction (TAC) model by inhibiting the proteolytic activation of HB-EGF signaling, exerting its antidiabetic effect by ameliorating insulin sensitivity through the inhibition of TNF-alpha production.

    价 格:¥电议型 号:T70280产 地:中国大陆

  • T7027EURYCOMANONE;东革阿里提取物Pasakbumin A;东革阿里提取物|||Pasakbumin A

    Eurycomanone (Pasakbumin A) is cytotoxic on HepG2 cells by inducing apoptosis through the up-regulation of p53 and Bax, and down-regulation of Bcl-2.Eurycomanone has anti-cancer activity, inhibits A549 lung cancer cell proliferation in a dose-dependent manner at concentrations ranging from 5 to 20 μg/ml.

    价 格:¥电议型 号:T7027产 地:中国大陆

  • T6885Marimastat;马立马司他BB2516|||KB-R8898|||TA2516;BB2516|||马立马司他|||KB-R8898|||TA2516

    Marimastat (BB2516) (BB-2516) is a potent, broad spectrum matrix metalloprotease (MMP) inhibitor. MMP-9 (IC50=3 nM), MMP-1 (IC50=5 nM), MMP-2 (IC50=6 nM), MMP-14 (IC50=9 nM)and MMP-7 (IC50=13 nM).

    价 格:¥电议型 号:T6885产 地:中国大陆

  • T67864TH1760化合物TH1760MKB

    TH1760 (MKB) is an inhibitor of NUDIX-type 15 (NUDT15, IC50= 25 nM). TH1760 can sensitize cells to 6-thioguanine by increasing the accumulation of 6-thio- (d) GTP in nucleic acids. TH1760 can enhance the anti-leukemia effect of thiopurine.

    价 格:¥电议型 号:T67864产 地:中国大陆

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