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  • T72791AChE/MAO-B-IN-3；化合物 AChE/MAO-B-IN-3AChE/MAO-B-IN-3

    AChE/MAO-B-IN-3 is a dual inhibitor targeting both acetylcholinesterase (AChE) and monoamine oxidase B (MAO-B), exhibiting inhibitory concentrations (IC50s) of 0.0257 μM and 0.0456 μM against human AChE and MAO-B, respectively. This compound holds potential for Alzheimer’s disease research.

    价 格：￥电议型 号：T72791产 地：中国大陆

  • T72454AChE/BChE/MAO-B-IN-4；化合物 AChE/BChE/MAO-B-IN-4AChE/BChE/MAO-B-IN-4

    AChE/BChE/MAO-B-IN-4, an indan-1-one derivative, serves as a potent inhibitor for both monoamine oxidase B (MAO-B) and acetylcholinesterase/butyrylcholinesterase (AChE/BChE) enzymes. It exhibits a strong inhibitory effect on human MAO-B with an IC50 of 0.0393 μM, and demonstrates significant potency against human AChE and BChE enzymes with IC50 values of 0.0458 μM and 0.075 μM, respectively. Additionally, this compound displays notable antioxidant properties and the ability to prevent β-amyloid

    价 格：￥电议型 号：T72454产 地：中国大陆

  • T72453AChE/BChE/MAO-B-IN-3；化合物 AChE/BChE/MAO-B-IN-3AChE/BChE/MAO-B-IN-3

    AChE/BChE/MAO-B-IN-3, an indan-1-one derivative, serves as a potent inhibitor of human monoamine oxidase B (MAO-B) with an IC50 of 0.0359 μM, demonstrating significant inhibitory effects on acetylcholinesterase (AChE) and butyrylcholinesterase (BChE) with IC50 values of 0.0473 μM and 0.0782 μM, respectively. Exhibiting notable antioxidant activity, AChE/BChE/MAO-B-IN-3 holds considerable promise for Alzheimer´s disease (AD) research.

    价 格：￥电议型 号：T72453产 地：中国大陆

  • T72452AChE/BChE/MAO-B-IN-2；化合物 AChE/BChE/MAO-B-IN-2AChE/BChE/MAO-B-IN-2

    AChE/BChE/MAO-B-IN-2 is a potent inhibitor of the enzymes AChE, BChE, and MAO-B, with IC50 values of 48.2 nM, 83.9 nM, and 31.2 nM, respectively. It exhibits significant antioxidant activity and is applicable in Parkinson’s disease research.

    价 格：￥电议型 号：T72452产 地：中国大陆

  • T72018MAO-B ligand-1；化合物 MAO-B ligand-1MAO-B ligand-1

    MAO-B ligand-1 is a selective MAO-B inhibitor.

    价 格：￥电议型 号：T72018产 地：中国大陆

  • T67879hMAO-B-IN-5；化合物hMAO-B-IN-5hMAO-B-IN-5

    hMAO-B-IN-5 is a potent reversible and selective human monoamine oxidase hMAO-B inhibitor (IC50:0.12μM). hMAO-B-IN-5 can cross the blood-brain barrier and can be used in the study of Parkinson´s disease. It is a promising compound in the treatment and diagnosis of central nervous system diseases.

    价 格：￥电议型 号：T67879产 地：中国大陆

  • T67764hMAO-B-IN-4；化合物hMAO-B-IN-4hMAO-B-IN-4

    hMAO-B-IN-4 is a selective, reversible and blood–brain barrier (BBB) penetrable inhibitor of human monoamine oxidase-B (hMAO-B, IC50=0.067 μM, Ki= 0.03 μM, hMAO-A, IC50= 33.82 μM).

    价 格：￥电议型 号：T67764产 地：中国大陆

  • T64271MAO-B-IN-6；化合物 MAO-B-IN-6MAO-B-IN-6

    MAO-B-IN-6 is a selective, potent, orally active MAO-B inhibitor (IC50: 0.019 μM). MAO-B-IN-6 is superior to Safinamide both in vitro and in vivo.

    价 格：￥电议型 号：T64271产 地：中国大陆

  • T640365-HT6R/MAO-B modulator 1；化合物 5-HT6R/MAO-B modulator 15-HT6R/MAO-B modulator 1

    5-HT6R/MAO-B modulator 1 is an antagonist of 5-HT6R at Gs signaling and an irreversible inhibitor of MAO-B that exhibits glial protective activity. 5-HT6R/MAO-B modulator 1 exhibits induction of scopolamine-induced memory deficits.

    价 格：￥电议型 号：T64036产 地：中国大陆

  • T62172Dual AChE-MAO B-IN-1；化合物 Dual AChE-MAO B-IN-1Dual AChE-MAO B-IN-1

    Dual AChE-MAO B-IN-1 (compound 15) is a safe, metabolically stable neuroprotective agent.Dual AChE-MAO B-IN-1 is a potent, orally active CNS-permeable inhibitor of human AChE (IC50=550 nM) and MAO-B (IC50=8.2 nM), and has low in vitro activity against AChE and MAO-B with IC50 values of 550 nM, 8.2 nM respectively.

    价 格：￥电议型 号：T62172产 地：中国大陆

  • T62152Dual AChE-MAO B-IN-2；化合物 Dual AChE-MAO B-IN-2Dual AChE-MAO B-IN-2

    Dual AChE-MAO B-IN-2 is a potent, dual inhibitor of AChE (IC50: 0.12 μM) and MAO B (IC50: 0.01 μM).Dual AChE-MAO B-IN-2 has potential for Alzheimer´s disease studies.

    价 格：￥电议型 号：T62152产 地：中国大陆

  • T62062MAO-B-IN-7；化合物 MAO-B-IN-7MAO-B-IN-7

    MAO-B-IN-7 is a potent and blood-brain barrier permeable MAO-B and AChE inhibitor. MAO-B-IN-7 exhibits IC50 s of 41 nM, 87 nM and 0.3 μM for human AChE, electric eel AChE and MAO-B, respectively. MAO-B-IN-7 effectively alleviates oxidative stress and neuroinflammatory damage.

    价 格：￥电议型 号：T62062产 地：中国大陆

  • T61958MAO A/HDAC-IN-1；化合物 MAO A/HDAC-IN-1MAO A/HDAC-IN-1

    MAO A/HDAC-IN-1 is an effective monoamine oxidase A (MAO A) and HDAC dual inhibitor, which can be used for glioma research.

    价 格：￥电议型 号：T61958产 地：中国大陆

  • T61830MAO-B-IN-10；化合物 MAO-B-IN-10MAO-B-IN-10

    MAO-B-IN-10 (compound 4f) is a highly potent and selective inhibitor of MAO-B (monoamine oxidase-B). It effectively penetrates the blood-brain barrier and exhibits an IC50 of 5.3 μM. This compound demonstrates the ability to inhibit self-mediated Aβ (amyloid β) aggregation by 58.2% and disaggregate it by 43.3%. Thus, MAO-B-IN-10 holds promise for Alzheimer´s disease research [1].

    价 格：￥电议型 号：T61830产 地：中国大陆

  • T61321MAO-B-IN-12；化合物 MAO-B-IN-12MAO-B-IN-12

    MAO-B-IN-12 (Compound 16c) is a highly effective inhibitor of monoamine oxidase B (MAO-B), displaying significant potency with an IC50 value of 1.3 μM. Additionally, MAO-B-IN-12 exhibits notable neuroprotective activity [1].

    价 格：￥电议型 号：T61321产 地：中国大陆

  • T61131MAO-B-IN-11；化合物 MAO-B-IN-11MAO-B-IN-11

    MAO-B-IN-11, also known as Compound 8c, is a highly potent inhibitor of monoamine oxidase B (MAO-B), with an IC50 value of 1.3 μM. Additionally, MAO-B-IN-11 exhibits neuroprotective properties [1].

    价 格：￥电议型 号：T61131产 地：中国大陆

  • T61002hMAO-B-IN-3；化合物 hMAO-B-IN-3hMAO-B-IN-3

    hMAO-B-IN-3 (Compound 15) is a potent hMAO-B inhibitor (IC 50 = 47.4 nM) with favourable drug-like properties and a broad safety window. Therefore, hMAO-B-IN-3 is a suitable candidate for lead optimization and multitarget-directed ligands development [1].

    价 格：￥电议型 号：T61002产 地：中国大陆

  • T60947HDAC1/MAO-B-IN-1；化合物 HDAC1/MAO-B-IN-1HDAC1/MAO-B-IN-1

    HDAC1/MAO-B-IN-1 has the potential to be used in the Alzheimer’s disease research. HDAC1/MAO-B-IN-1 is a potent and selective inhibitor of HDAC1/MAO-B that can cross the blood-brain barrier. The IC50 values of HDAC1/MAO-B-IN-1 for HDAC1 and MAO-B are 21.4 nM and 99.0 nM, respectively [1].

    价 格：￥电议型 号：T60947产 地：中国大陆

  • T60932MAO-B-IN-8；化合物MAO-B-IN-8MAO-B-IN-8

    MAO-B-IN-8 is a highly potent and reversible inhibitor of monoamine oxidase-B (MAO-B), which also exhibits inhibitory effects on the microglial production of neuroinflammatory mediators. This compound is specifically designed for use in research related to neurodegenerative diseases [1].

    价 格：￥电议型 号：T60932产 地：中国大陆

  • T60891AChE/BChE/MAO-B-IN-1；化合物AChE/BChE/MAO-B-IN-1AChE/BChE/MAO-B-IN-1

    AChE/BChE/MAO-B-IN-1 is a reversible, non-time-dependent inhibitor of AChE, BChE and MAO-B that crosses the blood-brain barrier and exhibits inhibitory effects on hAChE, hBChE and hMAO-B with IC50s of 7.31, 0.56 and 26.1 μM, respectively. 1 had a neuroprotective effect and was not significantly cytotoxic.

    价 格：￥电议型 号：T60891产 地：中国大陆

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