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T9020GSK620Inhibitor,oral,GSK 620,phenotype,selectivity,GSK-620,whole,anti-inflammatory,GSK620,Epigenetic
GSK620 is a pan-BD2 inhibitor, which shows an anti-inflammatory phenotype in human whole blood with excellent broad selectivity, developability, and in vivo oral pharmacokinetics.GSK620 is highly selective for the BET-BD2 family of proteins, with >200-fold selectivity over all other bromodomains. GSK620 shows an anti-inflammatory phenotype in human whole blood.
价 格:¥电议型 号:T9020产 地:中国大陆
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TN2139Regaloside Blongiflorum,COX,Inhibitor,phenylpropanoid,iNOS,Lilium,Cyclooxygenase,COX-2,anti-inflamma
Regaloside B can inhibit the expression of iNOS and COX-2. Regaloside B is a phenylpropanoid isolated from Lilium longiflorum.It has anti-inflammatory activity.
价 格:¥电议型 号:TN2139产 地:中国大陆
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T6828ZL0420inhibit,Epigenetic Reader Domain,(E/Z)-ZL0420,BRD4,airway inflammation,immune response genes,Z
ZL0420 is a potent and selective bromodomain-containing protein 4 ( BRD4 ) inhibitor with nanomolar binding affinities to bromodomains (BDs) of BRD4. ZL0420 has IC 50 values of 27 nM against BRD4 BD1 and 32 nM against BRD4 BD2.
价 格:¥电议型 号:T6828产 地:中国大陆
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T7813α-MSHMelanocortin Receptor,hormone,αMSH,inhibit,Inhibitor,α MSH,neuroimmunomodulatory,inflammation,e
α-MSH is amide stimulates melanocortin 1 receptor that results in the activation of adenylyl cyclase.
价 格:¥电议型 号:T7813产 地:中国大陆
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TQ0248Alisol FInhibitor,Alisol F,immunosuppressive,triterpene,Hepatitis B virus,HBV,inhibit,virus
Alisol F is a natural product from Alisma plantago-aquatica Linn and has many activities.
价 格:¥电议型 号:TQ0248产 地:中国大陆
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T9424Temgicolurilinhibit,Inhibitor,γ-Aminobutyric acid Receptor,Mebicar,Temgicoluril,Gamma-aminobutyric a
Temgicoluril acts on?GABA Receptor.
价 格:¥电议型 号:T9424产 地:中国大陆
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T6557KU-0060648mTOR,inhibit,KU-0060648,Phosphoinositide 3-kinase,Inhibitor,Mammalian target of Rapamycin,
KU-0060648 is a dual inhibitor of DNA-PK and PI3Kα, PI3Kβ, PI3Kδ with IC50 of 8.6 nM and 4 nM, 0.5 nM, 0.1 nM respectively, less inhibition of PI3Kγ with IC50 of 0.59 μM.
价 格:¥电议型 号:T6557产 地:中国大陆
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TN2283Tripterifordininhibit,HIV,Human immunodeficiency virus,replication,Tripterifordin,anti-HIV,Inhibitor
Tripterifordin shows anti-HIV replication activity in H9 lymphocyte cells with an EC50 of 1 microgram/ml.
价 格:¥电议型 号:TN2283产 地:中国大陆
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T8233BRD3308β-cells,glucolipotoxicity,inflammatory,BRD-3308,Human immunodeficiency virus,BRD3308,Histone
BRD3308 is a highly selective inhibitor of HDAC3(IC50 of 54 nM), attenuating PE-mediated phosphorylation of ERK but not JNK.
价 格:¥电议型 号:T8233产 地:中国大陆
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TN6791Palvanilanti-inflammation,inhibit,HEK-293,Inhibitor,anti-nociceptive,Palvanil
Palvanil is a fast desensitizing agonist of TRPV1. it may be promising agents in the therapy of IBS since it modulates intestinal motility and reduces visceral pain.
价 格:¥电议型 号:TN6791产 地:中国大陆
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T6737ZaltoprofenCN-100,anti-inflammatory,COX-2,inhibit,non-steroidal,Zaltoprofen,Inhibitor,COX,NSAID,COX-
Zaltoprofen is a Cox-1 and Cox-2 inhibitor, which is used for the treatment of arthritis.
价 格:¥电议型 号:T6737产 地:中国大陆
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T8238Fosamprenavir Calcium SaltHuman immunodeficiency virus,HIV,Fosamprenavir Calcium Salt,Inhibitor,inhi
Fosamprenavir Calcium Salt (GW433908G) is a phosphate ester prodrug of the antiretroviral protease inhibitor Amprenavir, with improved solubility. Fosamprenavir Calcium Salt has Anti-HIV infection.
价 格:¥电议型 号:T8238产 地:中国大陆
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T8875CD73-IN-3Inhibitor,cancer,CD73 IN 3,CD-73-IN-3,CD73IN3,CD73,Immunosuppression,tumor,inhibit
LY-3475070 is a potent and selective CD73 inhibitor with an IC50 of 28 nM, and its use alone or in combination with pembrolizumab is currently being tested in patients with advanced cancer.
价 格:¥电议型 号:T8875产 地:中国大陆
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T6716ValsartanAngiotensin Receptor,Inhibitor,failure,blood,proinflammatory,aorta,CGP-48933,endothelial,cy
Valsartan is a tetrazole derivative and angiotensin II type 1 receptor blocker that is used to treat hypertension.
价 格:¥电议型 号:T6716产 地:中国大陆
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TN1259Complanatoside BAnti-Inflammatory,inhibit,Inhibitor,Complanatoside B,flavonoid
Complanatoside B is a natural product
价 格:¥电议型 号:TN1259产 地:中国大陆
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TQ0023LorediplonGABA Receptor,γ-Aminobutyric acid Receptor,inhibit,Inhibitor,Lorediplon,Gamma-aminobutyric
Lorediplon is a novel hypnotic drug acting as a GABAA receptor modulator, differentially active at the α1-subunit, associated with promoting sleep.
价 格:¥电议型 号:TQ0023产 地:中国大陆
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T6445CilomilastCilomilast,asthma,immunomodulatory,obstructive,Inhibitor,Phosphodiesterase (PDE),inhibit,P
Cilomilast is a potent PDE4 inhibitor with IC50 of about 110 nM, has anti-inflammatory activity and low central nervous system activity. Phase 3.
价 格:¥电议型 号:T6445产 地:中国大陆
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TQ0218DeoxyandrographolideInhibitor,proinflammatory,mRNA,inhibit,LPS,Interleukin Related,neurite,Deoxyandr
Deoxyandrographolide potentiates NGF-induced neurite outgrowth. Deoxyandrographolide suppresses the production of proinflammatory mediators TNF-α and IL-6.
价 格:¥电议型 号:TQ0218产 地:中国大陆
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T8961GW280264XGW-280264X,inhibit,GIC,Inhibitor,immunotherapy,metalloproteinases,Matrix metalloproteinases
GW280264X is an inhibitor of ADAM17 .
价 格:¥电议型 号:T8961产 地:中国大陆