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T6447Clindamycinbroad-spectrum,Antibiotic,Parasite,Inhibitor,Clindamycin,inhibit,bacteriostatic,Bacterial
Clindamycin dissociates peptidyl-tRNA from the bacterial ribosome, thereby disrupting bacterial protein synthesis. Clindamycin is a semisynthetic broad-spectrum antibiotic produced by chemical modification of the parent compound lincomycin.
价 格:¥电议型 号:T6447产 地:中国大陆
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T5530Mithramycin A
Mithramycin A, a DNA-binding antitumor antibiotic, is a selective specificity protein 1 (Sp1) inhibitor, which inhibits the growth of various cancers by decreasing Sp1 protein. Specificity protein 1 (Sp1) is a zinc-finger transcription factor that regulates multiple cellular functions and promotes tumor progression.
价 格:¥电议型 号:T5530产 地:中国大陆
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T6678SplitomicinInhibitor,Histone deacetylases,Splitomycin,HDAC,inhibit,Splitomicin
Splitomicin (IC50 of 60 μM), a specific inhibitor of NAD(+)-dependent histone deacetylase Sir2p, displays a high activity in a cell-based assay.
价 格:¥电议型 号:T6678产 地:中国大陆
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T9033BTYNBInhibitor,inhibit,ES-2,BTYNB,c-Myc,IMP1,Myc,IGROV-1,cancer cell,SK-MEL2
MDK6620?is an inhibitor of the oncofetal mRNA-binding protein IMP1 (IC50 = 5 μM for IMP1 binding to c-Myc mRNA).?MDK6620?downregulates β-TrCP1 mRNA and reduces activation of nuclear transcriptional factors-kappa B (NF-κB).?It disrupts this enhancer function by impairing IGF2 mRNA-binding protein 1 (IGF2BP1)-RNA association
价 格:¥电议型 号:T9033产 地:中国大陆
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T7166GNE-493GNE493,Mammalian target of Rapamycin,PI3K,Inhibitor,inhibit,GNE-493,Phosphoinositide 3-kinase
GNE-493 is potent, selective, and orally available PI3K and mTOR inhibitor with potential anticancer activity.IC50s of 3.4 nM, 12 nM, 16 nM, 16 nM and 32 nM for PI3Kα, PI3Kβ, PI3Kδ, PI3Kγ and mTOR,respectively.
价 格:¥电议型 号:T7166产 地:中国大陆
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T60104Mycophenolic acid-β-D-glucuronide solution
Mycophenolic acid glucuronide is the glucuronide metabolite of mycophenolic acid in human plasma.
价 格:¥电议型 号:T60104产 地:中国大陆
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TN6729Azadiradioneanti-nociceptive,antimycobacterial,Inhibitor,Heat shock proteins,inhibit,HSF1 Activator,
Azadiradione (AZD) from the methanolic extract of seeds of Azadirachta indica
价 格:¥电议型 号:TN6729产 地:中国大陆
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T6731WYE-354inhibit,Apoptosis,WYE354,WYE-354,WYE 354,Inhibitor,Autophagy,Mammalian target of Rapamycin,mT
WYE-354(IC50=5 nM) is an effective, selective and ATP-competitive mTOR inhibitor. It blocks mTORC2/P-AKT(S473) and mTORC1/P-S6K(T389), not P-AKT(T308). The selectivity for mTOR is higher than PI3Kα (>100-fold) and PI3Kγ (>500-fold).
价 格:¥电议型 号:T6731产 地:中国大陆
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T8641VancomycinInhibitor,Vancomycin,Antibiotic,inhibit,Autophagy,Bacterial
Vancomycin is an antibiotic used to treat serious bacterial infections by stopping the growth of bacteria.
价 格:¥电议型 号:T8641产 地:中国大陆
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T962810074-A4Inhibitor,10074-A4,10074-A-4,anticancer,cycle,CDK4,inhibit,cell,c-Myc,10074A4,Myc,CCND2,1007
10074-A4 is a c-Myc binding compound that associates with c-Myc370–409 and behaves like a “ligand cloud” around a “protein cloud”, with distinct features from that of a non-binding ligand.
价 格:¥电议型 号:T9628产 地:中国大陆
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T7865DanofloxacinInhibitor,Antibiotic,DNA-gyrase,respiratory,mycoplasma,inhibit,Fluoroquinolone,Danofloxa
Danofloxacin is a fluoroquinolone antibiotic used in veterinary medicine.
价 格:¥电议型 号:T7865产 地:中国大陆
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T6758AnisomycinAnisomycin,Bacterial,Inhibitor,JNK,DNA/RNA Synthesis,inhibit,Antibiotic,Apoptosis
Anisomycin is an antibiotic isolated from various Streptomyces species. It interferes with protein and DNA synthesis by inhibiting peptidyl transferase or the 80S ribosome system.
价 格:¥电议型 号:T6758产 地:中国大陆
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T8504DianemycinAntibiotic,Dianemycin,Nanchangmycin,Bacterial,inhibit,Inhibitor
Dianemycin is a broad spectrum polyether antibiotic, inhibits gram-positive bacteria. Nanchangmycin is a broad spectrum antiviral active against Zika virus
价 格:¥电议型 号:T8504产 地:中国大陆
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T6730WAY-600inhibit,Inhibitor,mTOR,WAY 600,WAY-600,Mammalian target of Rapamycin
WAY-600 is a potent, ATP-competitive and selective inhibitor of mTOR with IC50 of 9 nM; blocks mTORC1/P-S6K(T389) and mTORC2/P-AKT(S473) but not P-AKT(T308); selective for mTOR than PI3Kα (>100-fold) and PI3Kγ (>500-fold).
价 格:¥电议型 号:T6730产 地:中国大陆
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T9533BC-LI-0186Aminoacyl-tRNA Synthetase,RagD,rapamycin-resistant,BCLI0186,tRNA Synthetase, aaRS,H460,KRA
BC-LI-0186 is a potent and selective inhibitor of the interaction of Leucyl-tRNA synthetase (LRS) and Ras-related GTP-binding protein D (RagD) with IC50 of 46.11 nM. BC-LI-0186 competitively binds the RagD interaction site of LRS with Kd of 42.1 nM and has no effect on LRS-vps34, LRS-eprs, RagB-RagD association, mTORC1 complex formation. BC-LI-0186 potently inhibits the activity of tumor-associated MTOR mutants and the growth of rapamycin-resistant cancer cells. BC-LI-0186 can be used for lung c
价 格:¥电议型 号:T9533产 地:中国大陆
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T6402AzomycinAntibiotic,Azomycin,Inhibitor,Bacterial,inhibit
Azomycin is an antimicrobial antibiotic produced by a strain of Nocardia mesenterica.
价 格:¥电议型 号:T6402产 地:中国大陆
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T21572Erythromycin A enol etherInhibitor,inhibit,Acidic,Erythromycin A enol ether,degradation
Erythromycin A enol ether is a degradation product of Erythromycin A which is a macrolide antibiotic.
价 格:¥电议型 号:T21572产 地:中国大陆
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T7148JOSAMYCINinhibit,EN141,Inhibitor,Antibiotic,EN 141,JOSAMYCIN,Bacterial
JOSAMYCIN is a macrolide antibiotic exhibiting antimicrobial activity. The dissociation constant Kd from ribosome for Josamycin is 5.5 nM.
价 格:¥电议型 号:T7148产 地:中国大陆
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T7343PF-04979064Inhibitor,Phosphoinositide 3-kinase,Mammalian target of Rapamycin,PF 04979064,PF04979064,
PF-04979064 is a potent and selective PI3K and mTOR dual kinase inhibitor(Ki of 0.13 nM and 1.42 nM,respectively).
价 格:¥电议型 号:T7343产 地:中国大陆
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T9605Sangivamycincells,Nucleoside Antimetabolite/Analog,Sangivamycin,antitumor,NSC-65346,PKC,MCF7,NSC6534
Sangivamycin is an effective inhibitor of protein kinase C (PKC, Ki = 10 μM). Sangivamycin exhibits antiproliferative activity against a variety of human cancers.
价 格:¥电议型 号:T9605产 地:中国大陆