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T9641Aβ42-IN-2Aβ42 IN 2,Aβ42IN2
Aβ42-IN-2 is a γ-secretase modulator (patent WO2016070107, compound example 36). Aβ42-IN-2 exhibits an IC50 of 6.5 nM for Αβ42. Aβ42-IN-2 has research value in Alzheimer´s disease.
价 格:¥电议型 号:T9641产 地:中国大陆
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TP1174Endothelin-2 (49-69), humanpeptide,21-amino,inhibit,Human endothelin 2,vasoactive,acid,ET-RB,Endothe
Endothelin-2, human is a 21-amino acid vasoactive peptide that binds to G-protein-linked transmembrane receptors, ET-RA and ET-RB.
价 格:¥电议型 号:TP1174产 地:中国大陆
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T9700EZH2-IN-2EZH2IN2,EZH-2-IN-2,EZH2 IN 2
EZH2-IN-2 is a EZH2 inhibitor with an IC50 of 64 nM (Patent WO2018133795A1, Compound Example 69).
价 格:¥电议型 号:T9700产 地:中国大陆
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T9711OGT-IN-2OGT,mono- acylglycerol acyltransferase,articular diseases,Inhibitor,articular cartilage,Acyl
OGT-IN-2 is a potent O-GlcNAc transferase (OGT) inhibitor. OGT-IN-2 inhibits sOGT and ncOGT with IC50 values of 30 μM and 53 μM, respectively[1]. OGT-IN-2 can be used for the research of articular diseases[1].
价 格:¥电议型 号:T9711产 地:中国大陆
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T9377ASK1-IN-2colitis,ulcerative,signal-regulating,ASK1 IN 2,ASK1IN2,inhibit,MAP kinase kinase kinase, ME
ASK1-IN-2 is a potent and orally active inhibitor of apoptosis signal-regulating kinase 1 (ASK1), with an IC50 of 32.8 nM. ASK1-IN-2 can potentially be used as a therapeutic strategy for ulcerative colitis[1].
价 格:¥电议型 号:T9377产 地:中国大陆
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T7514N2-MethylguanosineN2-Methylguanosine,inhibit,Nucleoside Antimetabolite/Analog,N-2-Methylguanosine,In
N2-methylguanosine is a modified nucleoside of tRNA that occurs at several specific locations in many tRNA´s
价 格:¥电议型 号:T7514产 地:中国大陆
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T67857(Z)-4-(5-((5-(4-bromophenyl)furan-2-yl)methylene)-4-oxo-2-thioxothiazolidin-3-yl)butanoic acid
(Z)-4-(5-((5-(4-bromophenyl)furan-2-yl)methylene)-4-oxo-2-thioxothiazolidin-3-yl)butanoic acid is an ASK1 inhibitor, IC50 = 0.2 μM.
价 格:¥电议型 号:T67857产 地:中国大陆
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T7639Deltorphin 2inhibit,Deltorphin2,Inhibitor,Deltorphin 2,Opioid Receptor,Deltorphin-2
Deltorphin 2(TFA) is an agonist of δ opioid receptor(IC50:0.41 nM)
价 格:¥电议型 号:T7639产 地:中国大陆
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T9156CDC25B-IN-2Inhibitor,CDC-25B-IN-2,CDC25BIN2,Phosphatase,CDC25B IN 2,inhibit
BIA is an inhibitor of the interaction between TMBIM6 and mTORC2, which ultimately blocks AKT activation and cancer progression.
价 格:¥电议型 号:T9156产 地:中国大陆
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T97523-(7,7-dimethyl-5-oxo-6,7-dihydro-5H-pyrrolo[3,4-b]pyridin-2-yl)-1H-indole-7-carbonitrile3 (7,7 dime
3-[7 ,7- dimethyl-5-oxo -6H-pyrrolo[3,4-b]pyridin-2-yI]-1H-indole-7 -carbonitrile is an androgen receptor modulator.
价 格:¥电议型 号:T9752产 地:中国大陆
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T9696β-catenin-IN-2HCT116,inhibit,cancer,β-catenin,cell,Beta catenin,HT-29,Tcf/4,Colorectal,Inhibitor,β c
β-catenin-IN-2 is a potent inhibitor of β-catenin that can be used in colorectal cancer research.
价 格:¥电议型 号:T9696产 地:中国大陆
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TQ0110ROCK-IN-2inhibit,Rho-kinase,Rho-associated protein kinase,Azaindole-1,ROCKIN2,Rho-associated kinase,
Azaindole 1 is a selective and ATP-competitive ROCK inhibitor with IC50 of 0.6 and 1.1 nM for human ROCK-1 and ROCK-2.
价 格:¥电议型 号:TQ0110产 地:中国大陆
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T7263SMS2-IN-2Inhibitor,SMS-2-IN-2,SMS2 IN 2,SMS2IN2,inhibit
SMS2-IN-2 is a potent, selective and orally active sphingomyelin synthase 2 (SMS2) inhibitor, (IC50s of 100 and 56 μM for SMS2 and SMS1, respectively). SMS2-IN-2 has anti-chronic inflammatory activity.
价 格:¥电议型 号:T7263产 地:中国大陆
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T9560MAO-B-IN-2MAO B IN 2,MAOBIN2
MAO-B-IN-2 is a selective and competitive inhibitor of MAO-B and BChE with IC 50 values of 0.51 and 7.00 μM, respectively. MAO-B-IN-2 attenuates H2O2-induced cellular damage via good ROS scavenging property.
价 格:¥电议型 号:T9560产 地:中国大陆
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T12379PD-1-IN-22PD 1 IN 22,PD1IN22
PD-1-IN-22 is a potent programmed cell death-1 (PD-1)/programmed cell death-ligand 1 (PD-L1) interaction inhibitor(IC50 of 92.3 nM).
价 格:¥电议型 号:T12379产 地:中国大陆
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T60086TTBK1-IN-2
TTBK1-IN-2 is an inhibitor of Tau-Tubulin kinase (TTBK1) with IC50s of 0.24 and 4.22 ?M. TTBK1-IN-2 reduces TDP-43 phosphorylation both in cell cultures and the spinal cord of transgenic TDP-43 mice.
价 格:¥电议型 号:T60086产 地:中国大陆
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T67868Oleana-2,12-dien-28-oic acidOleana2,12dien28oicacid
Oleana-2,12-dien-28-oic acid is an HBsAg and HBeAg inhibitor that obviously inhibit HBV deoxyribonucleic acid (HBV-DNA) replication in HepG2.2.15 cells. Oleana-2,12-dien-28-oic acid for the study of hepatitis B virus infection.
价 格:¥电议型 号:T67868产 地:中国大陆
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T89125-ETHYL-4,5,6,7-TETRAHYDRO-THIAZOLO[5,4-C]PYRIDIN-2-YLAMINE5ETHYL4,5,6,7TETRAHYDROTHIAZOLO[5,4C]PYRI
5-ETHYL-4,5,6,7-TETRAHYDRO-THIAZOLO[5,4-C]PYRIDIN-2-YLAMINE targets PLK1.
价 格:¥电议型 号:T8912产 地:中国大陆
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T64359(E)-1-[(E)-3-(4-hydroxy-3-methoxyphenyl)acryloyl]-3- (3,4,5-trimethoxybenzylidene) piperidin-2-one(E
(E)-1-[(E)-3-(4-hydroxy-3-methoxyphenyl)acryloyl]-3- (3,4,5-trimethoxybenzylidene) piperidin-2-one is an anti-inflammatory agent. It exhibited dose-dependent inhibition of LPS-induced release of TNF-a and IL-6 in active RAW 264.7 mouse macrophages, IC50=3.69uM and 3.68uM, respectively.
价 格:¥电议型 号:T64359产 地:中国大陆
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T9394CHIKV-IN-2Dihydroorotate Dehydrogenase,CHIKV,DHODH,virus,inhibit,CHIKV IN 2,Chikungunya,Inhibitor,CH
CHIKV-IN-2 shows inhibitory activity against a cellular target Dihydroorotate Dehydrogenase (DHODH), which interacts with various viruses and regulate their replication via depleting intracellular pyrimidine pools. Therefore, CHIKV-IN-2 is a potent inhibitor against Chikungunya virus (CHIKV), with excellent cellular antiviral activity (EC90=270 nM) and improved liver microsomal stability[1].
价 格:¥电议型 号:T9394产 地:中国大陆