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产品数:86101
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T9351NirmatrelvirPF 07321332,inhibit,Antiviral,Nirmatrelvir,virus,Inhibitor,PF07321332,PF-07321332,SARS c
PF-07321332 is a potent and orally active inhibitor of SARS-CoV 3C-like protease (3CLPRO) .
价 格:¥电议型 号:T9351产 地:中国大陆
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T8463PF-06873600PF06873600,PF 06873600
PF-06873600 is a selective and orally bioavailable cyclin-dependent kinase (CDK) inhibitor(CDK2, CDK4 and CDK6 with Ki of 0.09 nM, 0.13 nM and 0.16 nM, respectively), has potential antineoplastic activity.
价 格:¥电议型 号:T8463产 地:中国大陆
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TN1406DihydrokaempferolApoptosis,Dihydrokaempferol,Inhibitor,Bcl-2 Family,inhibit
Aromadendrin is a natural product. It induces apoptosis and inhibits Bcl-2 and Bcl-xL expression, possesses anti-inflammatory, antioxidant, and anti-diabetic properties, it exhibits anti-inflammatory activity
价 格:¥电议型 号:TN1406产 地:中国大陆
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T28374PF-06651481-00
PF-06651481-00 is a Bosutinib analog and a Bcr-Abl inhibitor.
价 格:¥电议型 号:T28374产 地:中国大陆
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T16515PF 750
PF 750 is a selective and covalent inhibitor of FAAH. PF 750 shows IC50s varying from 16.2 to 595 nM in different incubation times.
价 格:¥电议型 号:T16515产 地:中国大陆
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T7729PF-06454589Inhibitor,G2019S LRRK2,inhibit,LRRK2,parkinson’s disease,PF06454589,PF 06454589,PF-064545
PF-06454589 is a potent inhibitor of LRRK2.
价 格:¥电议型 号:T7729产 地:中国大陆
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T12414PF-00356231 hydrochloridePF 00356231 hydrochloride,PF00356231 hydrochloride
PF-00356231 hydrochloride is an inhibitor of matrix metalloproteinase MMP-12 with IC50 of 1.4 μM.
价 格:¥电议型 号:T12414产 地:中国大陆
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T7502PF 05089771 tosylatePF 05089771 tosylate,TTX-R,pain,Na channels,PF-05089771,neuropathy,diabetic,Sodi
PF-05089771 is a voltage-gated sodium channel 1.7 (Nav1.7) blocker (IC50: 11, 16, 33, and 20 nM for 5N11S, 5A11L, 5A11S, and 5A11L Nav1.7 splice variants, respectively). It is selective for Nav1.7 over Nav1.1-1.6 and 1.8 channels (IC50: 0.11-25 μM), L-type calcium, and KvLQT and hERG potassium channels (IC50: ≥10 μM), as well as human and cynomolgus monkey TRPV1 receptors (IC50: 10/20 μM). PF-05089771 is also 1, 000-fold selective for half-inactivated over resting Nav1.7 channels, and mutation o
价 格:¥电议型 号:T7502产 地:中国大陆
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T7767FMoc-Val-Cit-PAB-PNPFMocValCitPABPNP,ADC Linkers,inhibit,Antibody-drug conjugates linkers,Inhibitor,
Fmoc-Val-Cit-PAB-PNP is a linker for Antibody-Drug-Conjugation (ADC).
价 格:¥电议型 号:T7767产 地:中国大陆
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T21548PF-4981517
CYP3cide (PF-4981517) is a efficient, specific and time-dependent inhibitor of cytochrome P4503A4 (CYP3A4). The IC 50 values for Midazolam 1’-hydroxylase activity are 0.03 μM, 17 μM, and 71 μM for CYP3A4, CYP3A5, and CYP3A7, respectively. CYP3cide is able to be used to distinguish the contributions of CYP3A4 versus CYP3A5 on drug metabolism [1].
价 格:¥电议型 号:T21548产 地:中国大陆
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T8840PF-543 hydrochlorideNrf-2,PF543 hydrochloride,anti-cancer,sphingosine-competitive,S1P,Sphingosine Ki
PF-543 inhibits SphK1 with a K(i) of 3.6 nM, is sphingosine-competitive and is more than 100-fold selective for SphK1 over the SphK2 isoform.
价 格:¥电议型 号:T8840产 地:中国大陆
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T9253CPFX4158CPFX4158,CPFX-4158
CPFX4158 is a mannose deriviative and an antibacterial agent that is potentially useful in transgenic humanized- CEACAM6 mouse.
价 格:¥电议型 号:T9253产 地:中国大陆
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TN1823Kaempferol 3-O-β-D-galactopyranosideTrifolin,Inhibitor,inhibit,Kaempferol 3 O β D galactopyranoside,
Kaempferol-3-O-galactoside has antioxidant, anti-inflammatory and antinociceptive activities.
价 格:¥电议型 号:TN1823产 地:中国大陆
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T9458PF-00835231Inhibitor,SARS coronavirus,PF00835231,PF-00835231,SARS CoV-2,COVID-19,SARS-CoV,SARS CoV-1
PF-00835231 is a CoV-2 cysteine 3C-like protease (3CLpro) inhibitor, with IC50s of 0.27 nM and 4 nM for SARS CoV-2 and SARS CoV-1 3CLpro, respectively.PF-00835231 is the active compound of the first anti-3CLpro regimen in clinical trials.
价 格:¥电议型 号:T9458产 地:中国大陆
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TN1818Kaempferol 3-O-β-D-glucuronidecytokine,Inhibitor,inhibit,mice,secretion,Interleukin Related,RAW 264.
Kaempferol 3-O-β-D-glucuronidee has antioxidant activity. Flavonoid glucuronides can be deconjugated by microsomal α?-glucuronidase from various human cells.
价 格:¥电议型 号:TN1818产 地:中国大陆
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T9592OATD-01inhibit,CHIT1,OATD-01,chitinase,antifibrotic,IPF,pulmonary fibrosis,OATD01,OATD 01,Inhibitor
OATD-01 is a highly active inhibitor of both Chitotriosidase (CHIT1) and acidic mammalian chitinase (AMCase).
价 格:¥电议型 号:T9592产 地:中国大陆
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TN6719Kaempferol-3-O-β-D-glucosyl(1-2)rhamnosideKaempferol 3 O β D glucosyl(1 2)rhamnoside,Kaempferol3OβDg
Kaempferol-3-O-β-D-glucosyl(1-2)rhamnoside is a natural peoduct isolated from Arabian jasmine
价 格:¥电议型 号:TN6719产 地:中国大陆
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TN5137TetramethylkaempferolTetramethylkaempferol
Tetramethylkaempferol is a PPARγ agonist, it can improve insulin sensitivity by increasing the levels of adiponectin, an important adipocytokine associated with insulin sensitivity in adipose tissue. Tetramethylkaempferol can concentration-dependently enhance the accumulation of triglyceride, a marker of adipogenesis.
价 格:¥电议型 号:TN5137产 地:中国大陆
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TQ0037Abrocitinibinhibit,Abrocitinib,Inhibitor,JAK,PF04965842,Janus kinase,PF 04965842
Abrocitinib (PF-04965842) is a potent, specific and orally-active JAK1 inhibitor (IC50s: 29/803 nM for JAK1/2).
价 格:¥电议型 号:TQ0037产 地:中国大陆
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T8876PF-06882961 TrisPF 06882961 Tris,PF06882961 Tris
PF-06882961 Tris is an orally bioavailable glucagon-like peptide-1 receptor (GLP-1R) agonist.
价 格:¥电议型 号:T8876产 地:中国大陆