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T80071PKCζ/ι pseudosubstrate inhibitor;化合物 PKCζ/ι pseudosubstrate inhibitorPKCζ/ι pseudosubstrate inhibito
PKCζ/ι pseudosubstrate inhibitor demonstrates comprehensive inhibitory activity across the protein kinase C (PKC) family and is associated with the induction of memory impairment [1].
价 格:¥电议型 号:T80071产 地:中国大陆
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T80070PKCβII Peptide Inhibitor I;化合物 PKCβII Peptide Inhibitor IPKCβII Peptide Inhibitor I
PKCβII Peptide Inhibitor I, a specific PKCβII inhibitor, exhibits cardioprotective properties in a rat cardiac ischemia/reperfusion injury model and mitigates vascular endothelial dysfunction [1].
价 格:¥电议型 号:T80070产 地:中国大陆
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T7885Afuresertib hydrochloride化合物Afuresertib hydrochlorideAfuresertib|||PKC|||Protein kinase C
Afuresertib hydrochloride is an inhibitor of Akt kinase (Kis of 0.08/2/2.6 nM for Akt1/Akt2/Akt3 respectively)
价 格:¥电议型 号:T7885产 地:中国大陆
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T76412PKCδ Peptide Substrate;化合物 PKCδ Peptide SubstratePKCδ Peptide Substrate
PKCδ Peptide Substrate is a highly specific substrate for the δ-type of Protein kinase C, composed of a sequence that mirrors murine eEF-1α (422-443) and includes Thr-431 [1].
价 格:¥电议型 号:T76412产 地:中国大陆
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T75885PKC β pseudosubstrate TFA;化合物 PKC β pseudosubstrate TFAPKC β pseudosubstrate TFA
PKC β pseudosubstrate TFA is a selective cell-permeable inhibitor of PKC [1] .
价 格:¥电议型 号:T75885产 地:中国大陆
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T72919PKCiota-IN-1;化合物 PKCiota-IN-1PKCiota-IN-1
PKCiota-IN-1 is a potent inhibitor of PKCiota (PKC-ι), exhibiting an IC50 of 2.7 nM. Additionally, it displays inhibitory activity against PKC-α and PKC-ε, with IC50 values of 45 nM and 450 nM, respectively.
价 格:¥电议型 号:T72919产 地:中国大陆
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T71930aPKC-I;化合物 aPKC-IaPKC-I
aPKC-I is an inhibitor of atypical protein kinase C (aPKC ) which inhibits both PKCζ and PKCι with high specificity and prevents VEGF-induced endothelial permeability in cell culture and in vivo, thereby blocking ischemia-reperfusion (IR)-induced permeability.
价 格:¥电议型 号:T71930产 地:中国大陆
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T62945Aurora A/PKC-IN-1;化合物 Aurora A/PKC-IN-1Aurora A/PKC-IN-1
Aurora A/PKC-IN-1 (Compound 2e) is a potent dual inhibitor of Aurora A (AurA) and PKC (α, β1, β2, θ), acting on AurA (IC50: 6.9 nM) and PKCα (IC50: 16.9 nM). Aurora A/PKC-IN-1 showed anti-proliferative and anti-metastatic effects on breast cancer cells.
价 格:¥电议型 号:T62945产 地:中国大陆
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T61604PKC-IN-4;化合物 PKC-IN-4PKC-IN-4
PKC-IN-4 (compound 7l) is a highly potent and orally active inhibitor of atypical protein kinase C (aPKC), exhibiting an IC 50 value of 0.52 μM. In vitro studies have demonstrated that PKC-IN-4 effectively suppresses NF-κB activity induced by TNF-α. Moreover, this compound effectively impedes the permeability of the retinal vasculature, induced by both VEGF and TNFα. [1]
价 格:¥电议型 号:T61604产 地:中国大陆
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T5817PKC-theta inhibitor hcl;化合物PKC-theta inhibitor hclPKC-theta inhibitor;PKC-theta inhibitor
PKC-theta inhibitor hcl is a selective PKC-θinhibitor(IC50:12 nM).
价 格:¥电议型 号:T5817产 地:中国大陆
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T5423PKC-theta inhibitor;化合物PKC-theta inhibitorPKC-theta inhibitor
PKC-theta inhibitor is PKC-θinhibitor, with an IC50 of 12 nM.
价 格:¥电议型 号:T5423产 地:中国大陆
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T35827LPKCε Inhibitor Peptide acetate;化合物PKCε Inhibitor Peptide acetatePKCε Inhibitor Peptide acetate(18268
PKCε Inhibitor Peptide acetate is a selective PKCε inhibitor containing the site for its specific receptor for activated C kinase (RACK). PKCε Inhibitor Peptide acetate inhibits the translocation of PKCε, but not α-, β-, and δPKC.
价 格:¥电议型 号:T35827L产 地:中国大陆
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T35827Epsilon-V1-2;PKCε Inhibitor PeptidePKCε Inhibitor Peptide|||Protein Kinase C? Inhibitor Peptide|||?V
Protein kinase C (PKC ) is a calcium-independent, phospholipid- and diacylglycerol-dependent serine/threonine kinase involved in diverse signaling pathways, including those involved in neuronal signaling, cytoskeletal function, and inflammation.[1] PKC inhibitor peptide is a synthetic peptide corresponding to an amino acid sequence found in the amino terminal C2 domain of most mammalian forms of PKC .[2] It selectively and reversibly inhibits the translocation of PKC to intracellular membrane
价 格:¥电议型 号:T35827产 地:中国大陆
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T35826PKC fragment (530-558);PKC fragment (530-558)PKC fragment (530-558)
PKC fragment (530-558) is a peptide fragment of protein kinase C (PKC) and is a potent PKC activator. Protein Kinase C (530-558) significantly inhibits osteoclastic bone resorption.
价 格:¥电议型 号:T35826产 地:中国大陆
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T3211Midostaurin;米哚妥林N-Benzoylstaurosporine|||PKC412|||CGP41231|||CGP 41251;米哚妥林|||N-Benzoylstaurosporine
PKC412(Midostaurin (PKC412); CGP41231; CGP41251) is a broad spectrum protein kinase inhibitor. Midostaurin inhibits protein kinase C alpha (PKCalpha), vascular endothelial growth factor receptor 2 (VEGFR2), c-kit, platelet-derived growth factor receptor (PDGFR) and FMS-like tyrosine kinase 3 (FLT3) tyrosine kinases, which may result in disruption of the cell cycle, inhibition of proliferation, apoptosis, and inhibition of angiogenesis in susceptible tumors.
价 格:¥电议型 号:T3211产 地:中国大陆
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T12496PKC-theta inhibitor 1;化合物 T12496PKC-theta inhibitor 1
PKC-theta inhibitor 1 is an inhibitor of PKCθ (Ki of 6 nM)
价 格:¥电议型 号:T12496产 地:中国大陆
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T12494PKC-IN-1;化合物PKC-IN-1PKC-IN-1
PKC-IN-1 is an ATP-competitive and reversible conventional PKC enzymes inhibitor (PKCα, PKCβI, PKCβII, PKCθ, PKCγ, PKC mu and PKCε with IC50s of 2.3, 8.1, 7.6, 25.6, 57.5, 314, 808 nM, respectively).
价 格:¥电议型 号:T12494产 地:中国大陆
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T12280O-Desmethyl Midostaurin;化合物 T12280CGP62221|||O-Desmethyl PKC412;CGP62221|||O-Desmethyl PKC412
O-Desmethyl Midostaurin is the active Midostaurin metabolite via cytochrome P450 liver enzyme metabolism.
价 格:¥电议型 号:T12280产 地:中国大陆
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T12036Midostaurin-D5;化合物 T12036PKC412-D5|||CGP 41251-D5;PKC412-D5|||CGP 41251-D5
Midostaurin-D5 is a deuterium labeled Midostaurin.
价 格:¥电议型 号:T12036产 地:中国大陆