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产品数：86101
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T41168SJF 0661；SJF 0661SJF 0661
SJF 0661 is the negative control for SJF 0628. Binds BRAF without inducing degradation.
价 格：￥电议型 号：T41168产 地：中国大陆
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T36246SJF 8240；SJF 8240SJF 8240
c-MET degrader. Comprises MET inhibitor foretinib (GSK 1363089) joined by a linker to a von Hippel-Lindau (VHL) recruiting ligand. Degrades c-MET within 6 hours in vitro. Inhibits agonist-driven AKT phosphorylation and GTL16 cell proliferation (IC50 = 66.7 nM). Also degrades exon-14-deleted c-MET in Hs746T cells.
价 格：￥电议型 号：T36246产 地：中国大陆
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T36245SJF 1528；SJF 1528SJF 1528
Potent EGFR Degrader (DC50 values are 39.2 nM for wild-type EGFR in OVCAR8 cells and 736 nM for Exon20Ins mutated EGFR in HeLa cells). Also degrades HER2. Comprises the EGFR inhibitor lapatinib joined by a linker to a von Hippel-Lindau (VHL) recruiting ligand. Inhibits proliferation of HER2-driven breast cancer cell lines (IC50 = 102 nM for SKBr3 cells).
价 格：￥电议型 号：T36245产 地：中国大陆
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T36244SJF 1521；SJF 1521SJF 1521
Selective EGFR Degrader. Comprises the EGFR inhibitor lapatinib joined by a linker to a von Hippel-Lindau (VHL) recruiting ligand. Exhibits selectivity for EGFR, including mutant forms, over HER2. Induces degradation of EGFR in OVCAR8 cells.
价 格：￥电议型 号：T36244产 地：中国大陆
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T35477BSJ-Bump；BSJ-BumpBSJ-Bump
Negative control for BSJ-03-123 . Displays binding and no degradation of Cdk6 in vitro.
价 格：￥电议型 号：T35477产 地：中国大陆
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T35476BSJ-04-132；BSJ-04-132BSJ-04-132
Selective Cdk4 degrader. Degrades Cdk4 in Molt-4 cells, with no effect on Cdk6 levels. Displays cereblon-dependent degradation.
价 格：￥电议型 号：T35476产 地：中国大陆
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T30775CC-8017；化合物 T30775XSKMMEVRGHPMSJ-UHFFFAOYSA-N|||M11(CC-8017)|||CC8017|||SCHEMBL2168383|||CC 8017；XSK
CC-8017 is a bio-active chemical.
价 格：￥电议型 号：T30775产 地：中国大陆
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T30600BSJ-03-204；化合物 T30600BSJ03204；BSJ03204
BSJ-03-204 is a selective Cdk4/6 degrader.
价 格：￥电议型 号：T30600产 地：中国大陆
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T28786SJA6017；化合物 T28786SJA-6017|||Calpain Inhibitor VI|||Calpain-In-4|||SJA 6017|||Calpain Inhibitor 4；SJ
SJA6017 is a inhibitor of calpain-1 (IC50 = 7.5 nM) and calpain-2 ( IC50 = 78 nM). SJA6017 also inhibits cathepsins B (IC50s = 15 nM) and cathepsins L (IC50s = 1.6 nM). SJA6017 reduces apoptotic cell death, preserves spinal cord tissue and improves functional outcome.
价 格：￥电议型 号：T28786产 地：中国大陆
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T27750KSJ0001；化合物 T27750KSJ-0001|||KSJ 0001；KSJ-0001|||KSJ 0001
KSJ0001, a HBV virus inhibitor, inhibits HBV replication in transfected Huh7 cells.
价 格：￥电议型 号：T27750产 地：中国大陆
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T27625IQP-0528；化合物IQP-0528SJ-3991|||SJ3991|||IQP0528；SJ-3991|||SJ3991|||IQP0528
IQP-0528 is a potent non-nucleoside reverse transcriptase inhibitor (NNRTI) that has potential for the treatment of HIV infection by blocking viral entry and shows antiviral activity as a microbicidal gel. . IQP-0528 showed inhibition of both HIV-1 and HIV-2, with an EC50 of 0.2 nM for HIV-1 and 100 nM for HIV-2.
价 格：￥电议型 号：T27625产 地：中国大陆
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T24835SSJ-183；化合物 T24835SSJ183|||SSJ 183；SSJ183|||SSJ 183
SSJ-183 is an antimalarial agent.
价 格：￥电议型 号：T24835产 地：中国大陆
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T24794SJ-3366；化合物 T24794SJ 3366；SJ 3366
SJ3366 is a unique and highly potent nonnucleoside reverse transcriptase human immunodeficiency virus type 1 and HIV-2 inhibitor.
价 格：￥电议型 号：T24794产 地：中国大陆
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T19876Simiarenol；化合物 T19876UNII-6OU4M247SJ|||Simiaren-3beta-ol|||beta-Simiarenol；UNII-6OU4M247SJ|||Simiare
Simiarenol may have leishmanicidal activity against Leishmania donovani promastigotes in vitro.
价 格：￥电议型 号：T19876产 地：中国大陆
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T18682SJFδ；化合物 T18682SJFδ
SJFδ is a 10-atom linker PROTAC. SJFδ degrades p38δ with a DC50 of 46.17 nM, but does not degrade p38α, p38β, or p38γ[1].
价 格：￥电议型 号：T18682产 地：中国大陆
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T18681SJFα；化合物 T18681SJFα
SJFα is a 13-atom linker PROTAC. SJFα degrades p38α with a DC50 of 7.16 nM, but is far less effective at degrading p38δ (DC50=299 nM) and does not degrade the other p38 isoforms (β and γ) at concentrations up to 2.5 μM[1].
价 格：￥电议型 号：T18681产 地：中国大陆
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T17313(+)-SJ733；化合物n(+)-SJ733SJ000557733；SJ000557733
(+)-SJ733 (SJ000557733) is a potent Na+-ATPase PfATP4 inhibitor with antimalarial activity for the study of malaria.
价 格：￥电议型 号：T17313产 地：中国大陆
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T16890SJG-136；化合物 T16890NSC-694501；NSC-694501
SJG-136 is a DNA cross-linking agent (XL50: 45 nM for pBR322 DNA).
价 格：￥电议型 号：T16890产 地：中国大陆
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T16889SJ572403；化合物SJ572403SJ403；SJ403
SJ572403 is an inhibitor of disordered protein p27 with Kd of 2.2 mM for specific regions within the D2 subdomain of p27-KID. SJ572403 can be used in studies about diseases with intrinsically disordered proteins.
价 格：￥电议型 号：T16889产 地：中国大陆
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T16888SJ-172550；化合物SJ-172550SJ-172550
SJ-172550 is a small molecule inhibitor of MDMX (EC50: 5 μM).
价 格：￥电议型 号：T16888产 地：中国大陆
