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T4536Pleconaril;普可那利VP 63843|||Win 63843|||Picovir;VP 63843|||Win 63843|||Picovir|||普可那利
Pleconaril (VP 63843) is a capsid inhibitor used previously to treat enterovirus infections. Pleconaril is effective in inhibiting replication (IC50: 50 nM).
价 格:¥电议型 号:T4536产 地:中国大陆
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T4434Tirapazamine;替拉扎明Tirazone|||Win59075|||SR4233|||SR259075;Tirazone|||Win59075|||SR4233|||替拉扎明|||SR259
Tirapazamine (Win59075) is a potent cytotoxic agent under hypoxic conditions, can induce apoptosis by inducing breaks in single and double-stranded DNA, as well as chromosomal breaks. The compound sensitizes cells to other ionizing radiation and other cytotoxic agents like cisplatin.
价 格:¥电议型 号:T4434产 地:中国大陆
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T36355Sydowinin B;Sydowinin BSydowinin B
Sydowinin B is a xanthone polyketide that has been found inA. sydowiiand has immunosuppressant activity.1It inhibits LPS- or concanavalin A-induced proliferation of isolated mouse splenic lymphocytes (IC50s = 19.2 and 20.8 μg/ml, respectively).2Sydowinin B inhibits superoxide generation in, and elastase release from, isolated human neutrophils induced by cytochalasin B and N-Formyl-Met-Leu-Phe with IC50values of 21.2 and 12.62 μM, respectively.3
价 格:¥电议型 号:T36355产 地:中国大陆
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T35782Swinholide A;猪苓内酯AMK-7684;MK-7684
Swinholide A is a polyketone compound that can be extracted from sponges and binds to actin to dimerize actin with Kd of about 50 nM. Swinholide A is a cytotoxin that stabilizes actin dimers and severs actin filaments. Swinholide A has antifungal activity and can damage the actin cytoskeleton of cells.
价 格:¥电议型 号:T35782产 地:中国大陆
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T35133WIN-68056;化合物 T35133WIN 68056;WIN 68056
WIN-68056 is a wetting agent in x-ray contrast compositions.
价 格:¥电议型 号:T35133产 地:中国大陆
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T3363Jervine蒜黎芦碱蒜黎芦碱|||Iervin|||11-Ketocyclopamine|||Jerwiny
The biological activity of Jervine (Jerwiny) is mediated via its interaction with the 7 passes transmembrane protein Smoothened. Jervine binds with and inhibits smoothened, which is an integral part of the Hedgehog signaling pathways. With smoothened inhibited, the GLI1 transcription cannot be activated and Hedgehog target genes cannot be transcribed.
价 格:¥电议型 号:T3363产 地:中国大陆
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T31530Disoxaril;化合物 T31530BRN 3626820|||WIN51711|||WIN-51711|||BRN-3626820|||WIN 51711|||WIN-51,711;BRN 36
Disoxaril (BRN 3626820, WIN 51711) is an anti-picornavirus agent that inhibits enterovirus replication by binding to a hydrophobic bag within the VP1 coat protein, thereby stabilizing virions and preventing their uncoating. When used in combination with Ambioxime and Bioxazole, there was a significant synergistic inhibition of poliovirus type 1 replication in FL cells.
价 格:¥电议型 号:T31530产 地:中国大陆
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T29158WIN 62,577;化合物 T29158WIN62,577|||WIN-62,577;WIN62,577|||WIN-62,577
WIN 62,577 is a allosteric antagonist of mAChR.
价 格:¥电议型 号:T29158产 地:中国大陆
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T29157WIN 51,708;化合物 WIN 51,708WIN51,708|||WIN-51,708;WIN51,708|||WIN-51,708
WIN 51,708 is a neurokinin receptor (NK1) antagonist.
价 格:¥电议型 号:T29157产 地:中国大陆
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T28844SR 271425;化合物 T28844SR-271425|||WIN 71425|||SR271425|||SW-71425|||SW-271425;SR-271425|||WIN 71425|||
SR 271425, a novel cytotoxic DNA-interacting agent, has broad antitumor activity in preclinical models.
价 格:¥电议型 号:T28844产 地:中国大陆
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T28282Oxypertine;化合物 T28282Win-18501|||Forit|||Win18501|||Win 18501;Win-18501|||Forit|||Win18501|||Win 185
Oxypertine is an indole-derivative antipsychotic with general properties similar to those of the chlorpromazine and phenothiazine. Oxypertine is used as a treatment for various psychoses including mania, schizophrenia, disturbed behaviour, and severe anxiety.
价 格:¥电议型 号:T28282产 地:中国大陆
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T28131Napamezole;化合物 T28131WIN51181|||WIN-51181|||WIN 51181;WIN51181|||WIN-51181|||WIN 51181
Napamezole is an α2 adrenergic receptor antagonist. Napamezole antagonizes methoxamine-induced contractions (alpha-1) of the rat vas deferens with a Kb of 135 nM. Napamezole reverses clonidine-induced decreased in twitch height in the electrically stimulated rat vas deferens.
价 格:¥电议型 号:T28131产 地:中国大陆
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T26330WIN 5063-3;化合物 T26330WIN-5063-3|||Thiamphenicol epimer|||WIN5063-3|||L-Thiamphenicol;WIN-5063-3|||Th
WIN 5063-3 is the enantiomeric analog of the antimicrobial Thiamphenicol.
价 格:¥电议型 号:T26330产 地:中国大陆
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T25756Lorajmine hydrochloride;化合物 T25756WIN 11831;WIN 11831
Lorajmine hydrochloride is used as a Cardiac Depressant (Antiarrhythmic).
价 格:¥电议型 号:T25756产 地:中国大陆
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T23536Xamoterol hemifumarate;富马酸扎莫特罗ICI 118587 hemifumarate|||Corwin hemifumarate;ICI 118587 hemifumarate|
Xamoterol hemifumarate is a potent and selective β1-adrenoceptor agonist.Xamoterol hemifumarate is a potential compound for the study of the relationship between cardiac arrhythmias and β1-adrenergic stimulation with IKr.
价 格:¥电议型 号:T23536产 地:中国大陆
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T23533WIN 18446;N,N’-八亚甲基双二氯乙酰胺WIN 18446
inhibitor of aldehyde dehydrogenase 1a2 (ALDH1a2)
价 格:¥电议型 号:T23533产 地:中国大陆
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T20824Cyanox CY 1790;抗氧化剂 TH-1790Lowinox 1790|||Irganox 3790|||Antioxidant 1790|||Irganox-3790|||DN 90;Low
Cyanox CY 1790 (Irganox-3790) is an agent with antioxidant activity.
价 格:¥电议型 号:T20824产 地:中国大陆
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T20139Butocarboxim;化合物 T20139CO 755|||Drawin 755;CO 755|||Drawin 755
Butocarboxime is used as an insecticide and acaricide.
价 格:¥电议型 号:T20139产 地:中国大陆
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T19309L1Endothelin 1 (swine, human) acetate;化合物Endothelin 1 (swine, human) acetateEndothelin 1 (swine, human
Endothelin 1 (swine, human) acetate is a synthetic peptide with the sequence of human and swine Endothelin 1. Endothelin 1 is a potent endogenous vasoconstrictor and acts through two types of receptors ETA and ETB.
价 格:¥电议型 号:T19309L1产 地:中国大陆
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T19309Endothelin 1 (swine, human);内皮缩血管肽 1 (猪,人)Endothelin 1 (swine, human)
Endothelin 1 (swine, human), a synthetic peptide mirroring the sequence of both human and swine Endothelin 1, functions as a robust endogenous vasoconstrictor by interacting with two receptor types, ETA and ETB.
价 格:¥电议型 号:T19309产 地:中国大陆