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T101113-Deazaadenosine hydrochloride
3-Deazaadenosine hydrochloride is an inhibitor of S-adenosylhomocysteine hydrolase (Ki: 3.9 μM). It has anti-inflammatory, anti-proliferative, and anti-HIV activity.
价 格:¥电议型 号:T10111产 地:中国大陆
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T0853Adenosine腺苷;D-Adenosine;Adenine riboside
Adenosine is a ribonucleoside comprised of adenine bound to ribose, with vasodilatory, antiarrhythmic and analgesic activities.
价 格:¥电议型 号:T0853产 地:中国大陆
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T0853AdenosineAdenosine,D-Adenosine,Adenine riboside
Adenosine is a ribonucleoside comprised of adenine bound to ribose, with vasodilatory, antiarrhythmic and analgesic activities.
价 格:¥电议型 号:T0853产 地:美洲
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T101113-Deazaadenosine hydrochloride3-Deazaadenosine hydrochloride
3-Deazaadenosine hydrochloride is an inhibitor of S-adenosylhomocysteine hydrolase (Ki: 3.9 ?M). It has anti-inflammatory, anti-proliferative, and anti-HIV activity.
价 格:¥电议型 号:T10111产 地:美洲
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T12159APNEAAPNEA,N6-[2-(4-Aminophenyl)ethyl]adenosine,
APNEA (N6-[2-(4-Aminophenyl)ethyl]adenosine) is a potent and non-selective agonist of A3 adenosine receptor.
价 格:¥电议型 号:T12159产 地:美洲
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T14127Adenosine A1 receptor activator T62Adenosine A1 receptor activator T62
Adenosine A1 receptor activator T62 is an allosteric enhancer of adenosine A1 receptor, and it produces antinociception in animal models of acute pain and also reduces hypersensitivity in models of inflammatory and nerve-injury pain[1][2][3].
价 格:¥电议型 号:T14127产 地:美洲
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T16166N-[(4-Aminophenyl)methyl]adenosineN-[(4-Aminophenyl)methyl]adenosine
N-[(4-Aminophenyl)methyl]adenosine is an adenosine receptor inhibitor (Ki: 29 nM for Rat ecto-5′-Nucleotidase).
价 格:¥电议型 号:T16166产 地:美洲
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T19464N6,N6-DimethyladenosineN6,N6-Dimethyladenosine
N6,N6-Dimethyladenosine is find in mycobacterium bovis Bacille Calmette-Guérin tRNA.
价 格:¥电议型 号:T19464产 地:美洲
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T838292’-Deoxy-1,N6-ethenoadenosine-5’-O-triphosphate sodium;化合物 2’-Deoxy-1,N6-ethenoadenosine-5’-O-tripho
2´-Deoxy-1,N6-ethenoadenosine-5´-O-triphosphate (ε-dATP), a fluorescent derivative of 2’-deoxyadenosine-5’-O-triphosphate (dATP), promotes sister chromatid exchange in stimulated primary mouse spleen T- and B lymphocytes with LPS or concanavalin A at concentrations of 50 to 150 ?M. Utilized in ambiguous base pairing investigations within vinyl chloride-induced mutagenesis research, ε-dATP, along with its related compound ε-ATP—which exhibits an emission peak at 415 nm after being exc
价 格:¥电议型 号:T83829产 地:中国大陆
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T83818Isoguanosine-5’-O-triphosphate sodium;化合物 Isoguanosine-5’-O-triphosphate sodium2-Hydroxyadenosine 5’
Isoguanosine-5´-O-triphosphate, an isomer of guanosine 5´-triphosphate (GTP) and a phosphorylated derivative of crotonoside, does not promote microtubule assembly like GTP. At a concentration of 2 mM, it hampers transcription and triggers T to C mutations in reverse transcriptase assays. This compound aids in assessing the substrate specificity of both phosphofructokinase and mutT homolog 1 (MTH1).
价 格:¥电议型 号:T83818产 地:中国大陆
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T83808Sp-Adenosine-5’-O-(1-thiotriphosphate) sodium;化合物 Sp-Adenosine-5’-O-(1-thiotriphosphate) sodiumSp-AT
Sp-Adenosine-5´-O-(1-thiotriphosphate) (Sp-ATP-α-S), an isomer of the ATP-α-S sulfur-containing nucleotide derivative and a purinergic P2Y1 receptor agonist, effectively increases calcium mobilization in HEK293 cells harboring the P2Y1 receptor with an EC50 of 9.4 nM for the human receptor. It also inhibits ADP-induced human isolated platelet aggregation with a Ki value of 4 μM and prompts relaxation in carbamoylcholine-tightened guinea pig taenia coli, achieving an EC50 of 426 nM.
价 格:¥电议型 号:T83808产 地:中国大陆
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T83807Rp-Adenosine-5’-O-(1-thiotriphosphate) sodium;化合物 Rp-Adenosine-5’-O-(1-thiotriphosphate) sodiumRp-AT
Rp-Adenosine-5´-O-(1-thiotriphosphate) (Rp-ATP-α-S), a sulfur-containing nucleotide derivative isomer and a purinergic P2Y1 receptor agonist, promotes calcium mobilization in HEK293 cells expressing the human P2Y1 receptor (EC50 = 75 nM). This compound exhibits binding affinity to washed isolated human platelets (Ki = 156 nM) and attenuates ADP-induced aggregation in human platelet-rich plasma (PRP; pA2 = 4.74), as well as inhibits cAMP production triggered by prostaglandin E1 (PGE1) in hu
价 格:¥电议型 号:T83807产 地:中国大陆
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T83806Sp-Adenosine-5’-O-(1-thiodiphosphate) sodium;化合物 Sp-Adenosine-5’-O-(1-thiodiphosphate) sodiumSp-ADP-
Sp-Adenosine-5’-O-(1-thiodiphosphate) (Sp-ADP-α-S), an isomer of the sulfur-containing nucleotide derivative ADP-α-S, functions as an inhibitor of phosphorylase kinase with an inhibition constant (Ki) of 0.53 ?M. This compound also promotes aggregation of isolated human platelets with an effective concentration (EC50) of 20 ?M and induces relaxation in carbamoylcholine-precontracted guinea pig taenia coli with an EC50 of 58.9 ?M.
价 格:¥电议型 号:T83806产 地:中国大陆
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T83805Rp-Adenosine-5’-O-(1-thiodiphosphate) sodium;化合物 Rp-Adenosine-5’-O-(1-thiodiphosphate) sodiumRp-ADP-
Rp-Adenosine-5´-O-(1-thiodiphosphate) (Rp-ADP-α-S), a sulfur-containing isomer of the nucleotide derivative ADP-α-S, acts as an inhibitor of phosphorylase kinase with an inhibition constant (Ki) of 0.53 ?M. This compound also induces aggregation in isolated human platelets with an effective concentration (EC50) of 20 ?M and promotes relaxation in guinea pig taenia coli that has been precontracted with carbamoylcholine, with an EC50 of 58.9 ?M.
价 格:¥电议型 号:T83805产 地:中国大陆
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T837897-Deazaadenosine-5’-O-diphosphate sodium;化合物 7-Deazaadenosine-5’-O-diphosphate sodium7-CH-ADP|||Tube
7-Deazaadenosine-5´-O-diphosphate, a modified nucleotide and metabolite of tubercidin, is generated through phosphorylation of tubercidin and further undergoes phosphorylation to become the active metabolite 7-deazaadenosine-5´-O-triphosphate.
价 格:¥电议型 号:T83789产 地:中国大陆
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T837868-Chloroadenosine-5’-triphosphate sodium;化合物 8-Chloroadenosine-5’-triphosphate sodium8-chloro ATP;8-
8-Chloroadenosine-5’-triphosphate (8-chloro ATP), a potent metabolite of the anticancer agent 8-chloro cyclic AMP (cAMP) and a nucleotide derivative, is produced through the biotransformation of 8-chloro cAMP into 8-chloroadenosine, followed by mono- and diphosphate intermediates. Accumulating for up to 12 hours after the administration of 8-chloro cAMP or 8-chloroadenosine, 8-chloro ATP inhibits cell growth, diminishes endogenous ATP levels, and reduces RNA synthesis without affecting DNA synth
价 格:¥电议型 号:T83786产 地:中国大陆
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T837852-Chloroadenosine-5’-O-diphosphate sodium;化合物 2-Chloroadenosine-5’-O-diphosphate sodium2-chloro ADP;
2-Chloroadenosine-5´-O-diphosphate, a purine nucleotide adenosine 5´diphosphate (ADP) derivative, demonstrates multiple biological activities. It promotes aggregation and inhibits cyclic AMP (cAMP) production, triggered by prostaglandin E2 (PGE2), in a concentration-dependent manner within isolated human platelet-rich plasma. Additionally, this compound facilitates the relaxation of precontracted isolated guinea pig taenia coli strips (pD2 = 6.74) and reduces arterial blood pressure
价 格:¥电议型 号:T83785产 地:中国大陆
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T834721,N6-Ethenoadenosine 5’-monophosphate sodium;化合物 1,N6-Ethenoadenosine 5’-monophosphate sodium1,N6-ε-
1,N6-Ethenoadenosine 5´-monophosphate sodium (1,N6-Etheno-AMP sodium), a fluorescent analog of adenosine 5´-monophosphate (AMP), serves as an effective probe for AMP-related systems due to its detectability at low concentrations. It is characterized by an excitation wavelength range of 250-300 nm and emits at 415 nm [1] [2].
价 格:¥电议型 号:T83472产 地:中国大陆
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T79812-Fluoroadenosine;2-氟腺苷2-Fluoroadenosine
2-Fluoroadenosine is a potent inhibitor of lymphocyte-mediated cytolysis.
价 格:¥电议型 号:T7981产 地:中国大陆
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T786342′-Thioadenosine;化合物 2′-ThioadenosinePD157432;PD157432
2´-Thioadenosine (PD157432) serves as a selective and irreversible inhibitor of ErbB-1 and ErbB-2 tyrosine kinases, demonstrating an IC50 value of 45 ?M against ErbB-2. It achieves covalent inactivation of ErbB-1 through modification of a cysteine residue within the enzyme´s active site [1].
价 格:¥电议型 号:T78634产 地:中国大陆