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T6147NortadalafilNortadalafil,Demethyl Tadalafil,
Nortadalafil is demethyl Tadalafil, which is a PDE5 inhibitor, treating erectile dysfunction (ED) ; and under the name Adcirca for the treatment of pulmonary arterial hypertensio.
价 格:¥电议型 号:T6147产 地:美洲
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T8343718-O-Demethylpederin;化合物 18-O-Demethylpederin18-O-Demethylpederin
18-O-Demethylpederin, a pederin analogue, is a natural polyketide first isolated from Paederus. This compound is a non-protein insect toxin and exhibits a range of biological activities, such as antibacterial, antiviral, and antitumor properties [1].
价 格:¥电议型 号:T83437产 地:中国大陆
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T833214-Demethyldeoxypodophyllotoxin;4’-去甲去氧鬼臼毒素4-Demethyldeoxypodophyllotoxin
4-Demethyldeoxypodophyllotoxin, an aryl tetrahydronaphthalenyl lignan analog from the roots of Podophyllum peltatum, has anticancer activity and modulates the Chk-2 signaling pathway in MCF-7 breast cancer cells.
价 格:¥电议型 号:T83321产 地:中国大陆
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T82861Bis-(-)-8-demethylmaritidine;化合物 Bis-(-)-8-demethylmaritidineBis-(-)-8-demethylmaritidine
Bis-(-)-8-demethylmaritidine, a natural alkaloid, serves as a potent inhibitor of acetylcholinesterase (AChE) and is utilized in Alzheimer´s disease research [1].
价 格:¥电议型 号:T82861产 地:中国大陆
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T81651Norrubrofusarin;化合物 NorrubrofusarinDidemethylasperxanthone;Didemethylasperxanthone
Norrubrofusarin (Didemethylasperxanthone) is a natural compound derived through demethylation of Compound III, a metabolite of Aspergillus niger [1].
价 格:¥电议型 号:T81651产 地:中国大陆
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T806543,3′-Bisdemethylpinoresinol;化合物 3,3′-Bisdemethylpinoresinol3,3′-Bisdemethylpinoresinol
3,3′-Bisdemethylpinoresinol, a natural lignin derivative, exhibits MMP-1 inhibitory activity in UVA-irradiated human dermal fibroblasts and can be isolated from the seeds of Morinda citrifolia [1].
价 格:¥电议型 号:T80654产 地:中国大陆
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T80652N-Demethyl Mifepristone;化合物 N-Demethyl MifepristoneRU 42633;RU 42633
N-Demethyl Mifepristone (RU 42633), an active metabolite of Mifepristone, exhibits 61% of the affinity for the glucocorticoid receptor relative to Mifepristone´s 100% [1].
价 格:¥电议型 号:T80652产 地:中国大陆
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T78587Se-Methylselenocysteine hydrochloride;化合物 Se-Methylselenocysteine hydrochlorideMethylselenocysteine
Se-Methylselenocysteine hydrochloride, a precursor to Methylselenol, exhibits significant cancer chemopreventive and antioxidant activities. It is orally bioavailable and promotes apoptosis [1] [2].
价 格:¥电议型 号:T78587产 地:中国大陆
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T782384′-DTMP;化合物4′-DTMP4-Demethyltrimethoprim;4-Demethyltrimethoprim
4′-DTMP (4-Demethyltrimethoprim) is a potent DHFR inhibitor with antimicrobial activity that induces additional local interactions with the enzyme and inhibits Escherichia coli.
价 格:¥电议型 号:T78238产 地:中国大陆
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T78095Demethyleneberberine chloride;化合物 Demethyleneberberine chlorideDemethyleneberberine chloride
Demethyleneberberine chloride, a natural mitochondria-targeted antioxidant, mitigates colitis in mice and suppresses inflammatory responses by blocking the NF-κB pathway and modulating the equilibrium of Th cells. It is also recognized as an AMPK activator for investigating non-alcoholic fatty liver disease (NAFLD) [1] [2] [3].
价 格:¥电议型 号:T78095产 地:中国大陆
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T7662α-Demethylnaproxen;化合物 α-Demethylnaproxenα-Demethylnaproxen
α-Demethylnaproxen is a competitive inhibitor of COX(Ki values of 21 and 19 μM for ovine COX-1 and -2, respectively)
价 格:¥电议型 号:T7662产 地:中国大陆
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T75637Demethylcantharidate disodium;化合物 Demethylcantharidate disodiumDemethylcantharidate disodium
Demethylcantharidate disodium, an endogenous metabolite, demonstrates significant anticancer efficacy against various cancers by inducing apoptosis in hepatocellular carcinoma cells through endoplasmic reticulum (ER) stress [1].
价 格:¥电议型 号:T75637产 地:中国大陆
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T75628Methyl ganoderate A acetonide;化合物 Methyl ganoderate A acetonideMethyl ganoderate A acetonide
Methyl ganoderate A acetonide, a lanostane triterpene derived from the fruiting bodies of Ganoderma lucidum, serves as a potent acetylcholinesterase (AChE) inhibitor with an IC50 value of 18.35 μM. Its efficacy in inhibiting AChE suggests potential utility in Alzheimer’s disease (AD) research [1].
价 格:¥电议型 号:T75628产 地:中国大陆
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T74722Demethyl bleomycin A2;化合物 Demethyl bleomycin A2Demethyl bleomycin A2
Demethyl bleomycin A2 is a Bleomycin congener. The DNA cleavage of demethyl bleomycin A2 is insensitive to the presence of 5-Methylcytidine [1] .
价 格:¥电议型 号:T74722产 地:中国大陆
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T741954′-Demethylnobiletin;化合物 4′-Demethylnobiletin4′-Demethylnobiletin
4′-Demethylnobiletin, a bioactive metabolite, activates the PKA/ERK/CREB signaling pathway, enhances CRE-mediated transcription in hippocampal neurons, and reverses memory impairment linked to NMDA receptor antagonism through ERK signaling stimulation [1].
价 格:¥电议型 号:T74195产 地:中国大陆
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T74021O-Demethyl Lenvatinib hydrochloride;化合物 O-Demethyl Lenvatinib hydrochlorideO-Demethyl Lenvatinib hyd
O-Demethyl Lenvatinib hydrochloride, a metabolite of Lenvatinib (E7080), is an orally administered multi-targeted tyrosine kinase inhibitor. It targets and inhibits VEGFR1-3, FGFR1-4, PDGFR, KIT, and RET, demonstrating potent antitumor activities [1] [2].
价 格:¥电议型 号:T74021产 地:中国大陆
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T74020O-Demethyl Lenvatinib;化合物 O-Demethyl LenvatinibO-Demethyl Lenvatinib
O-Demethyl Lenvatinib, a metabolite of Lenvatinib (E7080), is an orally administered, multi-targeted tyrosine kinase inhibitor. It effectively inhibits VEGFR1-3, FGFR1-4, PDGFR, KIT, and RET, demonstrating significant antitumor activities [1] [2].
价 格:¥电议型 号:T74020产 地:中国大陆
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T73604Methyl Green zinc chloride;化合物 Methyl Green zinc chlorideMethyl Green zinc chloride
Methyl Green Zinc Chloride, a potent fluorescent dye, is utilized for staining DNA in cells and electrophoretic gels. It serves as a direct measure of viability through microscopy and flow cytometry, exhibiting peaks at 633 and 677 nm [1] [2]. For storage, it should be protected from light.
价 格:¥电议型 号:T73604产 地:中国大陆
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T71429O-Demethyl apixaban sulfate;化合物 O-Demethyl apixaban sulfateO-Demethyl apixaban sulfate
O-Demethyl apixaban sulfate is a metabolite of Apixaban, a potent and highly selective factor Xa inhibitor. Apixaban is currently under development for treatment of arterial and venous thrombotic diseases.
价 格:¥电议型 号:T71429产 地:中国大陆
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T712899-O-Demethyltrigonostemone;化合物 9-O-Demethyltrigonostemone9-O-Demethyltrigonostemone
9-O-Demethyltrigonostemone is a natural IDO1 inhibitor, cytotoxic and antiplasmodial agent from the Roots of Strophioblachia fimbricalyx.
价 格:¥电议型 号:T71289产 地:中国大陆