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T12724RIG-1 modulator 1RIG-1 modulator 1
RIG-1 modulator 1 is useful for the treatment of viral infections including influenza virus, HBV, HCV and HIV.
价 格:¥电议型 号:T12724产 地:美洲
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T12922Sirtuin modulator 1Sirtuin modulator 1
Sirtuin modulator 1 is a SIRTl modulator, a homolog of SIRT3, (EC1.5 of < 1 μM)
价 格:¥电议型 号:T12922产 地:美洲
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T13182Toll-like receptor modulatorToll-like receptor modulator
Toll-like receptor modulator is a TLR7/8 modulator, which modulates immune function.
价 格:¥电议型 号:T13182产 地:美洲
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T15942MK-7622MK-7622,M1 receptor modulator,
MK-7622 is a modulator of muscarinic M1 receptor positive allosteric.
价 格:¥电议型 号:T15942产 地:美洲
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T8824CRBN modulator-1;化合物WUN29654WUN29654;WUN29654
CRBN modulator-1 (WUN29654) is a Thalidomide analog and CRBN modulator,has an IC50 of 3.5 μM and a Ki of 0.98 μM.
价 格:¥电议型 号:T8824产 地:中国大陆
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T83629Smurf-1 modulator CMP Example 20;Smurf-1抑制剂20Smurf-1-IN-20;Smurf-1-IN-20
Smurf-1 modulator CMP Example 20 (Smurf-1-IN-20) is a potent Smurf-1 modulator.
价 格:¥电议型 号:T83629产 地:中国大陆
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T83227A1AT modulator 1;化合物 A1AT modulator 1A1AT modulator 1
A1AT Modulator 1 potently inhibits Z α1-antitrypsin (A1AT) polymerization, exhibiting a pIC50 of 8.3 [1].
价 格:¥电议型 号:T83227产 地:中国大陆
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T82958ASGPR modulator-1;化合物 ASGPR modulator-1ASGPR modulator-1
Compound 5TJX (ASGPR modulator-1) is a macrocyclic compound utilized in the study of protein-protein interactions [1].
价 格:¥电议型 号:T82958产 地:中国大陆
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T82763CD33 splicing modulator 1 hydrochloride;化合物 CD33 splicing modulator 1 hydrochlorideCD33 splicing mod
CD33 Splicing Modulator 1 Hydrochloride (Compound 1) is a myeloid lineage cell surface receptor CD33/Siglec 3 modulator involved in regulating microglia activity. This compound promotes exon 2 skipping in cellular mRNA pools and has research potential in addressing neurodegenerative diseases, including Alzheimer´s disease [1].
价 格:¥电议型 号:T82763产 地:中国大陆
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T82439Estrogen receptor modulator 10;化合物 Estrogen receptor modulator 10Estrogen receptor modulator 10
Compound G-5b, an estrogen receptor modulator 10, functions as an estrogen receptor (ER) antagonist (IC50=6.7 nM) and degrader (DC50=0.4 nM). It has the capability to induce apoptosis and block cells at the G1/G0 phase, making it applicable in cancer research [1].
价 格:¥电议型 号:T82439产 地:中国大陆
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T82330GCase modulator-1;化合物 GCase modulator-1GCase modulator-1
GCase Modulator-1 (Compound 9g), a quinazoline derivative, functions as a glucosidase modulator with an AC50 value of 2.23 ?M [1].
价 格:¥电议型 号:T82330产 地:中国大陆
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T81631NV-354;化合物 NV-354Mitochondria modulator-1;Mitochondria modulator-1
Mitochondria Modulator-1, a mitochondrial regulator, enhances ATP production in mitochondria. It exhibits good oral bioavailability and blood-brain barrier permeability, along with robust plasma stability, showing promise for the investigation of mitochondrial diseases [1].
价 格:¥电议型 号:T81631产 地:中国大陆
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T79918α7β1 integrin modulator-1;化合物 α7β1 integrin modulator-1α7β1 integrin modulator-1
α7β1 Integrin Modulator-1 is a potent modulator with research potential for muscular dystrophy [1].
价 格:¥电议型 号:T79918产 地:中国大陆
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T79649CB1R/AMPK modulator 1;化合物 CB1R/AMPK modulator 1CB1R/AMPK modulator 1
Compound 38-S is an orally active CB1R/AMPK modulator with a K i of 0.81 nM and an IC50 of 3.9 nM for CB1R. This compound activates AMPK and has been shown to decrease food intake and body weight, in addition to enhancing glucose tolerance and insulin sensitivity [1].
价 格:¥电议型 号:T79649产 地:中国大陆
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T79618M3/PDE4 modulator-1;化合物 M3/PDE4 modulator-1M3/PDE4 modulator-1
M3/PDE4 Modulator-1 (compound 10f) serves as a bifunctional entity functioning both as an M3 mAChR antagonist and a PDE4 inhibitor. When administered intravenously at concentrations ranging from 10 to 1000 nM/kg, this compound effectively diminishes eosinophil influx into cysts within the OVA rat model [1].
价 格:¥电议型 号:T79618产 地:中国大陆
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T79504AMPA receptor modulator-6;化合物 AMPA receptor modulator-6AMPA receptor modulator-6
AMPA receptor modulator-6, an AMPA receptor positive allosteric modulator (PAM), is utilized in the research of neurological diseases [1].
价 格:¥电议型 号:T79504产 地:中国大陆
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T79191AMPA receptor modulator-5;化合物 AMPA receptor modulator-5AMPA receptor modulator-5
AMPA Receptor Modulator-5 (Example 217) serves as an AMPA receptor modulator, utilized in neurological disease research [1].
价 格:¥电议型 号:T79191产 地:中国大陆
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T79170Immuno modulator-1;化合物 Immuno modulator-1Immuno modulator-1
Immuno modulator-1 (compound 22) effectively suppresses the secretion of TNFα and IL-2 in human peripheral blood mononuclear cells (hPBMC) with IC50 values of 4.7 nM and 26 nM, respectively. Additionally, this compound exhibits a 20% inhibitory effect on the hERG potassium channel at a concentration of 3 μM [1].
价 格:¥电议型 号:T79170产 地:中国大陆
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T79131KAT modulator-1;化合物 KAT modulator-1KAT modulator-1
KAT modulator-1 (Compound 3), an epigenetics research tool, selectively interacts with the full-length p300 protein but not its catalytic domain [1].
价 格:¥电议型 号:T79131产 地:中国大陆
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T79109Estrogen receptor modulator 8;化合物 Estrogen receptor modulator 8Estrogen receptor modulator 8
Estrogen Receptor Modulator 8 (compound 4) is an orally active inhibitor targeting Estrogen Receptor/ERR α with potent efficacy (IC50 = 0.437 nM in MCF-7 cells) and effectively hampers MCF-7 cell proliferation (IC50 = 0.1 nM) [1].
价 格:¥电议型 号:T79109产 地:中国大陆