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T72216DPM-1001 trihydrochloride;化合物 DPM-1001 trihydrochlorideDPM-1001 trihydrochloride
DPM-1001 trihydrochloride, an analog of the specific protein-tyrosine phosphatase (PTP1B) inhibitor MSI-1436, is a potent, specific, non-competitive, orally active inhibitor of PTP1B with an IC50 of 100 nM, exhibiting anti-diabetic properties.
价 格:¥电议型 号:T72216产 地:中国大陆
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T69898NG25 trihydrochloride;化合物 NG25 trihydrochlorideNG25 trihydrochloride
NG25 trihydrochloride is a type II kinase inhibitor that inhibits MAP4K2 and TAK1. It also inhibits the Src family kinases Src and LYN and Abl family kinases as well as CSK, FER, and p38α. NG 25 prevents TNF-α-induced IKKα/β phosphorylation and IκB-α degradation in L929 cells. It inhibits secretion of IFN-α and IFN-β induced by CpG type B and CL097, respectively. NG 25 decreases cell viability of HCT116KRASWT, and to a greater degree of HCT116KRASG13D, colorectal cancer cells in a concentration
价 格:¥电议型 号:T69898产 地:中国大陆
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T69583AMD-3451 trihydrochloride;化合物 AMD-3451 trihydrochlorideAMD-3451 trihydrochloride
AMD-3451 trihydrochloride is a CCR5/CXCR4 dual antagonist that may be useful in the treatment of HIV.
价 格:¥电议型 号:T69583产 地:中国大陆
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T6526GW791343 trihydrochloride;化合物GW791343 3HClGW791343 3HCl;GW791343 3HCl
GW791343 trihydrochloride (GW791343 3HCl) is aHCl salt form of GW791343, which is a non-competitive allosteric modulator of human P2X7 receptor inhibitor with pIC50 of 7.
价 格:¥电议型 号:T6526产 地:中国大陆
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T64793N-(5-Aminopentyl)-2-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)oxy)acetamide trihydrochl
N-(5-Aminopentyl)-2-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)oxy)acetamide trihydrochloride is a useful organic compound for research related to life sciences and the catalog number is T64793.
价 格:¥电议型 号:T64793产 地:中国大陆
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T63476ARN5187 trihydrochloride;化合物 ARN5187 trihydrochlorideARN5187 trihydrochloride
ARN5187 trihydrochloride is a lysosomal REV-ERBβ ligand that inhibits REV-ERB-mediated transcriptional regulation and autophagy. ARN5187 trihydrochloride has lysosomal potency and cytotoxicity and induces apoptosis.
价 格:¥电议型 号:T63476产 地:中国大陆
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T6342NSC 23766 trihydrochloride;化合物NSC 23766 trihydrochlorideRac1 Inhibitor|||NSC 23766;Rac1 Inhibitor|||
NSC 23766 trihydrochloride (Rac1 Inhibitor) is an inhibitor of Rac GTPase targeting Rac activation by GEFs (IC50: ~50 μM); no inhibitory for the closely related targets, RhoA or Cdc42.
价 格:¥电议型 号:T6342产 地:中国大陆
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T62166KDOAM-25 trihydrochloride;化合物 KDOAM-25 trihydrochlorideKDOAM-25 trihydrochloride
KDOAM-25 trihydrochloride is a potent and highly selective inhibitor of histone lysine demethylase 5 (KDM5), acting on KDM5A (IC50: 71 nM), KDM5B (IC50: 19 nM), KDM5C (IC50: 69 nM), KDM5D (IC50: 69 nM). KDOAM-25 trihydrochloride enhances overall H3K4 methylation at the transcription start site and hinders the proliferation of multiple myeloma MM1S cells.
价 格:¥电议型 号:T62166产 地:中国大陆
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T6018Zosuquidar trihydrochloride;唑喹达三盐酸盐Zosuquidar (LY335979) 3HCl|||RS 33295-198 trihydrochloride|||RS 3
Zosuquidar trihydrochloride (LY-335979 trihydrochloride) is a potent modulator of P-glycoprotein-mediated multi-drug resistance with Ki of 60 nM. Phase 3.
价 格:¥电议型 号:T6018产 地:中国大陆
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T5516diABZI STING agonist-1 trihydrochloride;化合物T5516diABZI STING agonist-1 trihydrochloride
diABZI STING agonist-1 (trihydrochloride) is stimulator of interferon genes (STING) receptor agonist.
价 格:¥电议型 号:T5516产 地:中国大陆
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T5080Spermidine trihydrochloride;三盐酸亚精胺Spermidine hydrochloride|||4-Azaoctamethylenediamine trihydrochlor
Spermidine trihydrochloride (4-Azaoctamethylenediamine trihydrochloride), a natural polyamine, is a novel autophagy inducer and negatively modulates N-methyl-d-aspartate (NMDA).
价 格:¥电议型 号:T5080产 地:中国大陆
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T4457Pyridostatin Trihydrochloride;化合物Pyridostatin TrihydrochloridePyridostatin Trihydrochloride(free bas
Pyridostatin Trihydrochloride (RR-82 Trihydrochloride) is a G-quadruplexe stabilizer, with a Kd of 490 nM.
价 格:¥电议型 号:T4457产 地:中国大陆
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T41100Volasertib trihydrochloride伏拉塞替三盐酸盐BI6727trihydrochloride|||伏拉塞替三盐酸盐
Volasertib (BI 6727) trihydrochloride is a dihydropteridinone derivative that exhibits potent and selective inhibition of Polo-like kinase 1 (PLK1), PLK2, and PLK3. It acts as an orally active ATP-competitive inhibitor with an IC50 of 0.87 nM against PLK1. Additionally, Volasertib trihydrochloride demonstrates IC50 values of 5 nM and 56 nM against PLK2 and PLK3, respectively. Its mechanism of action includes inducing mitotic arrest and apoptosis. Furthermore, Volasertib trihydrochloride has been
价 格:¥电议型 号:T41100产 地:中国大陆
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T4057Hoechst 33258 trihydrochloride;化合物Hoechst 33258Hoechst 33258|||Pibenzimol|||Bisbenzimide|||H 33258 t
Hoechst 33258 trihydrochloride (Bisbenzimide) is a benzimidazole anti-filarial agent. it is fluorescent when it binds to certain nucleotides in DNA, thus providing a tool for the study of DNA replication. it also interferes with mitosis.
价 格:¥电议型 号:T4057产 地:中国大陆
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T39989LJQKD82 trihydrochloride;三盐酸JQKD82JQKD82 trihydrochloride
JQKD82 trihydrochloride, a cell-permeable and selective inhibitor of KDM5, enhances H3K4me3 levels and is utilized in multiple myeloma research.
价 格:¥电议型 号:T39989L产 地:中国大陆
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T39858NVP-BSK805 trihydrochlorideNVP-BSK805 trihydrochlorideNVP-BSK805 trihydrochloride
NVP-BSK805 trihydrochloride is a potent ATP-competitive inhibitor of JAK2, exhibiting IC50 values of 0.48 nM, 31.63 nM, 18.68 nM, and 10.76 nM against JAK2 JH1, JAK1 JH1, JAK3 JH1, and TYK2 JH1, respectively.
价 格:¥电议型 号:T39858产 地:中国大陆
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T39405Avotaciclib trihydrochlorideAvotaciclib trihydrochlorideBEY1107 trihydrochloride
Avotaciclib trihydrochloride, also known as BEY1107, is a highly effective and orally active inhibitor of cyclin dependent kinase 1 (CDK1). This compound is particularly valuable for researching locally advanced or metastatic pancreatic cancer.
价 格:¥电议型 号:T39405产 地:中国大陆
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T39061Hoechst 33342 analog trihydrochloride;Hoechst 33342 analog trihydrochlorideHoechst 33342 analog trih
Hoechst 33342 analog trihydrochloride, an analog of Hoechst 33342, serves as a fluorochrome by binding to the minor groove of DNA, facilitating the visualization of cellular DNA.
价 格:¥电议型 号:T39061产 地:中国大陆
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T38846Vevorisertib trihydrochloride;化合物Vevorisertib trihydrochlorideARQ 751 trihydrochloride;ARQ 751 trihy
Vevorisertib trihydrochloride (ARQ 751 trihydrochloride) is a selective and potent inhibitor of pan-AKT and AKT1-E17K mutations, inhibiting AKT1, AKT2 and AKT3. Vevorisertib trihydrochloride is used in the study of hepatocellular carcinoma and advanced solid tumours.
价 格:¥电议型 号:T38846产 地:中国大陆
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T38557Chitotriose trihydrochloride;壳三糖三盐酸盐Chitotriose trihydrochloride
Chitotriose trihydrochloride is an orally active chitooligosaccharide known for its antioxidant properties. It effectively inhibits the hydroxylation of benzoate to salicylate by H 2 O 2 in the presence of Cu 2+, with an IC 50 value of 80 μM.
价 格:¥电议型 号:T38557产 地:中国大陆