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T23445Anxiolytic/nonsedative agent-1
Anxiolytic/nonsedative agent-1 is a potent and selective GABAA agonist. Anxiolytic/nonsedative agent-1 shows appreciable affinity for the BzR in bovine brain membranes with Kis of 14, 121, 239 nM for α1β2γ2, α2β2γ2, α5β3γ2, respectively. Anxiolytic/nonsedative agent-1 shows α2 selective efficacy in vitro and anxioselective effects in vivo.
价 格:¥电议型 号:T23445产 地:中国大陆
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T10674Potassium Channel Activator 1
Potassium Channel Activator 1 can be used in studies about the treatment of disorders or conditions wherein the dopaminergic system is disrupted such as mood disorders ADHD, schizophrenia, and other psychotic states.
价 格:¥电议型 号:T10674产 地:中国大陆
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TN1110Shanzisideinhibit,Inhibitor,Iridoid,Shanziside,glucoside
Shanzhiside has immunosuppressive activity, it shows significant inhibition of IL-2 secretion by phorbol myristate acetate and anti-CD28 monoclonal antibody co-stimulated activation of human peripheral blood T cells.
价 格:¥电议型 号:TN1110产 地:中国大陆
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TP2490Palmitoyl Hexapeptide-12 AcetatePalmitoyl Hexapeptide 12 Acetate,Palmitoyl Hexapeptide12 Acetate
Palmitoyl hexapeptide-12 Acetate can promote collagen, elastin, and hyaluronic acid on proliferation. It can be used to improve the skin´s water content, increase the thickness of the dermis, reduce microgrooves.
价 格:¥电议型 号:TP2490产 地:中国大陆
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T8652CASP3 Activator 1541CASP-3 Activator 1541,CASP3 Activator 1541
CASP3 Activator 1541 is an activator of the proenzyme forms of caspase-3, and induces cell death.
价 格:¥电议型 号:T8652产 地:中国大陆
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T12424PF-06305591
PF-06305591 is an effective and selective blocker of voltage-gated sodium channel NaV1.8 (IC50 = 15 nM).
价 格:¥电议型 号:T12424产 地:中国大陆
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T22148(S)-Lisofylline(S)Lisofylline,(S) Lisofylline
(S)-Lisofylline is the inactive optical enantiomer of (R)-lisofylline which is an anti-inflammatory agent. (S)-Lisofylline is exclusively converted to pentoxifylline in human liver microsomes.
价 格:¥电议型 号:T22148产 地:中国大陆
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T16491PF-06446846 hydrochloridePF06446846 hydrochloride,PF 06446846 hydrochloride
PF-06446846 hydrochloride suppresses PCSK9 by inducing the ribosome to stall around codon 34. PF-06446846 hydrochloride is an orally active and highly selective inhibitor of translation of Proprotein convertase subtilisin/kexin type 9.
价 格:¥电议型 号:T16491产 地:中国大陆
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T7891IpidacrineIpidacrine,inhibit,cholinesterase,nootropic,Inhibitor,Cholinesterase (ChE),Alzheimer disea
Ipidacrine (NIK‐247) is an Antidementia Agent
价 格:¥电议型 号:T7891产 地:中国大陆
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T7658Dimethyl DL-Glutamate (hydrochloride)inhibit,Dimethyl DLGlutamate (hydrochloride),Inhibitor,Dimethyl
Dimethyl DL-glutamate is a cell-permeant glutamic acid derivative that enhances insulin release in response to glucose in isolated islets and in animal models of diabetes.
价 格:¥电议型 号:T7658产 地:中国大陆
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T7167Purvalanol BPurvalanol B,cdc2,inhibit,cyclin,CDK2,CDK5,CDK,Parasite,P. falciparum,ATP,NG95,Cyclin de
Purvalanol B is a CDK inhibitor that inhibits Cdk2/cyclin A, Cdk2/cyclin E, Cdk5/p35, and Cdk2/cyclin B (IC50s = 6, 9, 6, and 6 nM, respectively)
价 格:¥电议型 号:T7167产 地:中国大陆
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T9760IC 86621ATP,Buchwald-Hartwig amination,Inhibitor,IC-86621,IC86621,IC 86621,DSB,antitumor,inhibit,Apo
IC 86621 is a selective and reversible ATP-competitive inhibitor of DNA-PK with an IC50 of 120 nM. IC 86621 increases DNA double-strand break(DSB)-induced antitumor activity with an EC50 of 68 ?M for DNA-PK mediated cellular DSB repair.
价 格:¥电议型 号:T9760产 地:中国大陆
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TN2097Pomolic acidcancer,Inhibitor,inhibit,Randialic acid A,Pomolic acid,pentacyclic triterpene,ROS,Apopto
Pomolic acid has anti-cancer, anti-inflammatory and apoptotic activities, it can induce apoptosis in SK-OV-3 cells, which is mediated by the mitochondrial-mediated intrinsic and death receptor-induced extrinsic pathways.
价 格:¥电议型 号:TN2097产 地:中国大陆
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T9849HQ461cyclin K degrader,Cyclin dependent kinase,molecular glue,HQ461,HQ 461,HQ-461,CDK12 substrate ph
HQ461 is a molecular glue that promotes CDK12-DDB1 interaction to trigger cyclin K degradation, resulting in decreased CDK12 substrate phosphorylation, downregulation of DNA damage response genes, and cell death.
价 格:¥电议型 号:T9849产 地:中国大陆
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T14529LBentiromide acetate
Bentiromide acetate is a peptide used as a screening test for exocrine pancreatic insufficiency and to monitor the adequacy of supplemental pancreatic therapy. It is broken down by the pancreatic enzyme chymotrypsin, yielding p-aminobenzoic acid (PABA).
价 格:¥电议型 号:T14529L产 地:中国大陆
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TD00695-ROX, SEInhibitor,DNA sequencing,5 ROX, SE,5-ROX, SE,inhibit,5ROX, SE
5-ROX, SE is a labeling reagen used in the preparation of charge-modified dye-labeled Dideoxynucleotide Triphosphates (ddNTP) to "direct-load" DNA sequencing.
价 格:¥电议型 号:TD0069产 地:中国大陆
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T8309EIDD-2801EIDD 2801,EIDD2801
EIDD-2801 is an isopropylester prodrug of the ribonucleoside analog N 4-hydroxycytidine (EIDD-1931) that has shown broad influenza virus and multiple coronaviruses activity.
价 格:¥电议型 号:T8309产 地:中国大陆
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T38271TH1217
TH1217 is a potent and selective dCTPase pyrophosphatase 1 (dCTPase) inhibitor, with an IC50 of 47 nM. TH1217 enhances the cytotoxic effect of cytidine analogues in leukemia cells. TH1217 also could modulate SARS-Cov-2 interactors, so it shows activity of against COVID-19.
价 格:¥电议型 号:T38271产 地:中国大陆
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T2085PQ401MCF-7,PQ401,IGF-1R,cells,breast,PQ-401,PQ 401,inhibit,caspase,Apoptosis,autophosphorylation,can
PQ401 suppresses autophosphorylation of IGF-1R domain(IC50<1 μM).
价 格:¥电议型 号:T2085产 地:中国大陆
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T20170Apomorphine HCl hydrate
Apomorphine HCl hydrate is a nonselective dopamine agonist.
价 格:¥电议型 号:T20170产 地:中国大陆