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产品数：86101
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T1988DuvelisibDuvelisib,INK1197,IPI-145
Duvelisib is an orally bioavailable, highly selective and potent small molecule inhibitor of the delta and gamma isoforms of phosphoinositide-3 kinase (PI3K) with potential immunomodulating and antineoplastic activities.
价 格：￥电议型 号：T1988产 地：美洲
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T1997JNJ-31020028JNJ-31020028,JNJ31020028,JNJ 31020028
JNJ-31020028 is a selective brain penetrant antagonist of neuropeptide Y2 receptor with high affinity(pIC50=8.07, human; pIC50=8.22, rat); it exhibits >100-fold selectivity for Y2 versus human Y1/Y4/Y5 receptors.
价 格：￥电议型 号：T1997产 地：美洲
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T2008LY294002LY294002,SF 1101,NSC 697286
LY294002 is an inhibitor of PI3K (IC50s: 0.5/0.57/0.97 μM for PI3Kα/δ/β in cell-free assays). It also blocks autophagosome formation.
价 格：￥电议型 号：T2008产 地：美洲
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T2012OclacitinibOclacitinib,PF-03394197,
Oclacitinib(PF03394197) is a potent and selective JAKs inhibitor with IC50 of 10-99 nM; not inhibit a panel of 38 non-JAK kinases (IC50 ´s > 1000 nM).
价 格：￥电议型 号：T2012产 地：美洲
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T2016Ixazomib CitrateIxazomib Citrate,MLN9708,
MLN2238 suppresses the chymotrypsin-like proteolytic (β5) site of the 20S proteasome(Ki50=0.93 nM, IC50=3.4 nM/). The biologically active form of MLN9708 is MLN2238 in aqueous solutions or plasma.
价 格：￥电议型 号：T2016产 地：美洲
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T2090LexibulinLexibulin,CYT-997,
Lexibulin(CYT-997) is a potent tubulin polymerization inhibitor (IC50: 10-100 nM, in Y cell lines). Lexibulin blocks the formation of the mitotic spindle and leading to cell cycle arrest at the G2/M phase; this may result in disruption of the tumor vascul
价 格：￥电议型 号：T2090产 地：美洲
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T2115PexidartinibPexidartinib,PLX-3397,
Pexidartinib is a capsule formulation containing a small-molecule receptor tyrosine kinase (RTK) inhibitor of KIT, CSF1R and FLT3 with potential antineoplastic activity.
价 格：￥电议型 号：T2115产 地：美洲
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T2123LY2109761LY2109761
LY2157299 is a selective inhibitor of the TGF-β receptor I/II kinases (Ki: 38/300 nM).
价 格：￥电议型 号：T2123产 地：美洲
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T219710-Deacetylbaccatin III10-Deacetylbaccatin III
10-Deacetylbaccatin-III is an intermediate for taxol analog preparations with anti-cancer activity.
价 格：￥电议型 号：T2197产 地：美洲
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T2272BPR1J-097BPR1J-097,BPR1J097,BPR1J 097
BPR1J-097 is a novel FLT-3 inhibitor(IC50: 11±7 nM) with promising in vivo anti-tumor activities. It also inhibits FLT-3 D835Y (IC50: 3 nM).
价 格：￥电议型 号：T2272产 地：美洲
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T2297PIK-294PIK-294,PIK294,PIK 294
PIK-294 is a excellently specific p110δ inhibitor(IC50=10 nM).
价 格：￥电议型 号：T2297产 地：美洲
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T2397TopiroxostatTopiroxostat,FYX-051,
Topiroxostat is a selective xanthine oxidase inhibitor developed for treatment and management of hyperuricemia and gout.
价 格：￥电议型 号：T2397产 地：美洲
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T2464NSC319726NSC319726,ZMC1,
NSC319726, a mutant p53R175 reactivator, suppresses growth of fibroblasts that expresses the p53R175 mutation (IC50 = 8 nM).
价 格：￥电议型 号：T2464产 地：美洲
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T2494CilengitideCilengitide,EMD 121974,
Cilengitide is a potent integrin inhibitor for the αvβ3/5 receptor (IC50: 4.1/79 nM, in cell-free assays); ~10-fold selectivity against gpIIbIIIa.
价 格：￥电议型 号：T2494产 地：美洲
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T2497MPEP hydrochlorideMPEP hydrochloride
MPEP hydrochloride is an effective and highly specific non-competitive antagonist at the mGlu5 receptor subtype (IC50: 36 nM).
价 格：￥电议型 号：T2497产 地：美洲
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T2562EltrombopagEltrombopag,SB-497115-GR,SB-497115
Eltrombopag, an orally active thrombopoietin receptor agonist with megakaryopoiesis stimulating activity, binds to and stimulates the platelet thrombopoietin receptor (TPO-R or CD110).
价 格：￥电议型 号：T2562产 地：美洲
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T2597NorgestrelNorgestrel,WY-3707,SH-70850
Norgestrel is a synthetic progestin commonly used alone or in combination with an estrogen for contraception. Norgestrel suppresses the secretion of luteinizing and follicle-stimulating hormones (LH and FSH), thickens cervical mucus, and slows the transit
价 格：￥电议型 号：T2597产 地：美洲
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T2618LGK-974LGK-974,LGK974,LGK 974
LGK-974 is an effective and selective PORCN inhibitor and inhibits Wnt signaling (IC50: 0.4 nM) in TM3 cells. It has been used in trials studying the treatment of Metastatic Colorectal Cancer and Squamous Cell Carcinoma, Head And Neck.
价 格：￥电议型 号：T2618产 地：美洲
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T2669BerzosertibBerzosertib,VX-970,VE-822
VE-822 has been used in trials studying the treatment of Ovarian Neoplasms, Ovarian Serous Tumor, Adult Solid Neoplasm, Advanced Solid Tumor, and Advanced Solid Neoplasm, among others.
价 格：￥电议型 号：T2669产 地：美洲
