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T2094DanusertibDanusertib,PHA-739358,
Danusertib is a small-molecule 3-aminopyrazole derivative with potential antineoplastic activity. Danusertib binds to and inhibits the Aurora kinases, which may result in cell growth arrest and apoptosis in tumor cells in which Aurora kinases are overexpr
价 格:¥电议型 号:T2094产 地:美洲
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T2158Nutlin-3Nutlin-3,Nutlin3,Nutlin 3
Nutlin-3 is an MDM2 antagonist. Nutlin-3 inhibits the MDM2-p53 interaction (IC50: 0.09 μM) and activates p53. Antiproliferative agent; chemotherapeutic agent; induces apoptosis in Y cells.
价 格:¥电议型 号:T2158产 地:美洲
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T2236RU58841RU58841,HMR-3841,PSK-3841
RU 58841 is a specific androgen receptor antagonist or anti-androgen; RU 58841 has a significant effect on hair regrowth.
价 格:¥电议型 号:T2236产 地:美洲
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T2254A-205804A-205804,A205804,A 205804
A-205804 is a specific and effective inhibitor of E-selectin( IC50=20 nM ) and ICAM-1(IC50=25 nM) expression.
价 格:¥电议型 号:T2254产 地:美洲
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T2257AdipoRonAdipoRon,SC-396658,
AdipoRon is an orally bioavailable adiponectin receptor agonist. It can combine with AdipoR1/2 (KD: 1.8/3.1 μM).
价 格:¥电议型 号:T2257产 地:美洲
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T2258VER-50589VER-50589,VER50589,VER 50589
VER-50589 is a potent HSP90 inhibitor.
价 格:¥电议型 号:T2258产 地:美洲
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T2358ENMD-2076ENMD-2076,ENMD2076,ENMD 2076
ENMD-2076, a multi-targeted kinase inhibitor, has specific activity against Aurora A, Flt3, KDR/VEGFR2, Flt4/VEGFR3, FGFR1, FGFR2, Src, PDGFRα.
价 格:¥电议型 号:T2358产 地:美洲
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T2383PanobinostatPanobinostat,NVP-LBH589,LBH589
Panobinostat is a potent inhibitor of all HDACs (Kis: 0.6-31 nM for HDAC1-11).
价 格:¥电议型 号:T2383产 地:美洲
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T2511PlinabulinPlinabulin,NPI-2358,
Plinabulin (NPI-2358) is a vascular disrupting agent (VDA) against tubulin-depolymerizing tumor cells ( IC50: 9.8-18 nM). Plinabulin selectively targets and binds to the colchicine-binding site of tubulin, thereby interrupting equilibrium of microtubule d
价 格:¥电议型 号:T2511产 地:美洲
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T2543CabazitaxelCabazitaxel,RPR-116258A,taxoid XRP6258
Cabazitaxel is a taxane and antineoplastic agent which is currently used in the therapy of castration-resistant metastatic prostate cancer after failure of docetaxel.
价 格:¥电议型 号:T2543产 地:美洲
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T2558CladribineCladribine,2CdA,CldAdo
Cladribine, an adenosine deaminase inhibitor, is utilized in the treatment of lymphoproliferative diseases.
价 格:¥电议型 号:T2558产 地:美洲
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T2576Brivanib AlaninateBrivanib Alaninate,BMS-582664,
Brivanib Alaninate is the alaninate salt of a vascular endothelial growth factor receptor 2 (VEGFR2) inhibitor with potential antineoplastic activity. Brivanib strongly binds to and inhibits VEGFR2, a tyrosine kinase receptor expressed almost exclusively
价 格:¥电议型 号:T2576产 地:美洲
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T2580FormoterolFormoterol,Arformoterol,
Arformoterol is an adrenergic β-2 receptor agonist with a prolonged duration of action. It is used to manage asthma and in the treatment of chronic obstructive pulmonary disease.
价 格:¥电议型 号:T2580产 地:美洲
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T2583CilastatinCilastatin,MK0791,
Cilastatin is a renal dehydropeptidase-I and leukotriene D4 dipeptidase inhibitor. Since the antibiotic, IMIPENEM, is hydrolyzed by dehydropeptidase-I, which resides in the brush border of the renal tubule, cilastatin is administered with imipenem to incr
价 格:¥电议型 号:T2583产 地:美洲
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T2585BedaquilineBedaquiline,R207910,TMC207
Bedaquiline(TMC207; R207910) is an anti-tuberculosis drug which selectively inhibit the mycobacterial energy metabolism i.e. ATP synthesis and found to be effective against all states of Mycobacterium tuberculosis.
价 格:¥电议型 号:T2585产 地:美洲
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T2586CabozantinibCabozantinib,BMS-907351,XL184
Cabozantinib (XL184) is a potent pan-tyrosine kinases inhibitor that inhibits VEGFR2, c-Met, Kit, Axl, and Flt3 (IC50s: 0.035, 1.3, 4.6, 7 and 11.3 nM).
价 格:¥电议型 号:T2586产 地:美洲
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T2587Ecabet SodiumEcabet Sodium,TA-2711,TA-2711E
Ecabet sodium: a potential new agent in the management of distal colitis.
价 格:¥电议型 号:T2587产 地:美洲
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T2588IvacaftorIvacaftor,VX-770,Ivacaftor (VX-770)
Ivacaftor (VX-770) is a potentiator of CFTR targeting G551D-CFTR (EC50: 100 nM) and F508del-CFTR (EC50: 25 nM) in Fisher rat thyroid cells, respectively.
价 格:¥电议型 号:T2588产 地:美洲
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T2589Dalasetron Mesylate HydrateDalasetron Mesylate Hydrate,Dolasetron Mesylate hydrate,
Dolasetron mesylate, a selective serotonin receptor antagonist, competitively blocks the action of serotonin at 5HT3 receptors, resulting in suppression of chemotherapy- and radiotherapy-induced nausea and vomiting.
价 格:¥电议型 号:T2589产 地:美洲
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T2659GW 2580GW 2580,SC-203877,
GW2580 is a specific, oral-bioavailable CSF-1R inhibitor for c-FMS.
价 格:¥电议型 号:T2659产 地:美洲