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T79266Antihypertensive agent 2;化合物 Antihypertensive agent 2Antihypertensive agent 2
Antihypertensive agent 2 (Compound 4g) exhibits effective antagonistic activities against angiotensin II receptor 1 and reduces blood pressure with equal or greater potency than Losartan [1].
价 格:¥电议型 号:T79266产 地:中国大陆
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T7912(?)-Myrtenal;(1R)-(-)-桃金娘烯醛(1R)-(?)-Myrtenal;(1R)-(-)-桃金娘烯醛|||桃金娘烯醛|||(1R)-(?)-Myrtenal
(?)-Myrtenal ameliorates hyperglycemia by enhancing GLUT2 through Akt in the skeletal muscle and liver of diabetic rats.
价 格:¥电议型 号:T7912产 地:中国大陆
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T79106SORT-PGRN interaction inhibitor 3;化合物 SORT-PGRN interaction inhibitor 3SORT-PGRN interaction inhibit
SORT-PGRN Interaction Inhibitor 3 (Compound 13), with an IC50 value of 0.17 μM, acts as an inhibitor of the SORT-PGRN interaction, and is utilized in the study of neurodegenerative diseases [1].
价 格:¥电议型 号:T79106产 地:中国大陆
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T7896BYK204165;化合物BYK204165RT-017290;RT-017290
BYK204165 (RT-017290) is a potent PARP inhibitor (PARP1; IC50 = 44.67 nM for human recombinant PARP1 in an enzyme assay)
价 格:¥电议型 号:T7896产 地:中国大陆
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T78948NNRTIs-IN-1;化合物 NNRTIs-IN-1NNRTIs-IN-1
NNRTIs-IN-1 is a potent non-nucleoside reverse transcriptase inhibitor (NNRTI) with notable anti-resistance efficacy, effectively inhibiting both the wild-type HIV-1 and five mutant strains at EC50 values within the nanomolar range. This compound also exhibits favorable pharmacokinetic properties [1].
价 格:¥电议型 号:T78948产 地:中国大陆
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T78857SIRT5 inhibitor 9;化合物 SIRT5 inhibitor 9SIRT5 inhibitor 9
SIRT5 inhibitor 9 (compound 14), with an IC50 of 4.07 μM, is a competitive inhibitor of the sirtuin SIRT5, exhibiting potential anticancer properties [1].
价 格:¥电议型 号:T78857产 地:中国大陆
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T78856SIRT5 inhibitor 8;化合物 SIRT5 inhibitor 8SIRT5 inhibitor 8
SIRT5 inhibitor 8 (compound 10) serves as a competitive inhibitor of sirtuin SIRT5, exhibiting an IC50 of 5.38 μM, and possesses anticancer potential [1].
价 格:¥电议型 号:T78856产 地:中国大陆
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T7885Afuresertib hydrochloride化合物Afuresertib hydrochlorideAfuresertib|||PKC|||Protein kinase C
Afuresertib hydrochloride is an inhibitor of Akt kinase (Kis of 0.08/2/2.6 nM for Akt1/Akt2/Akt3 respectively)
价 格:¥电议型 号:T7885产 地:中国大陆
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T78803SIRT5 inhibitor 7;化合物 SIRT5 inhibitor 7SIRT5 inhibitor 7
SIRT5 inhibitor 7 (compound 58), a selective and substrate-competitive SIRT5 inhibitor, exhibits anti-inflammatory properties by modulating protein succinylation and attenuating pro-inflammatory cytokine release. It demonstrates renal protective effects and is active in vivo, showing efficacy in AKI mouse models subjected to lipopolysaccharide (LPS) and cecal ligation/perforation (CLP)-induced sepsis-related acute kidney injury [1].
价 格:¥电议型 号:T78803产 地:中国大陆
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T78802SIRT5 inhibitor 6;化合物 SIRT5 inhibitor 6SIRT5 inhibitor 6
SIRT5 Inhibitor 6 is a potent, selective, and substrate-competitive inhibitor of SIRT5, exhibiting an IC50 of 3.0 μM, and demonstrates therapeutic potential for treating septic acute kidney injury (AKI) in vivo [1].
价 格:¥电议型 号:T78802产 地:中国大陆
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T78737NNRTIs-IN-3;化合物 NNRTIs-IN-3NNRTIs-IN-3
NNRTIs-IN-3 (compound 8) is an HIV-1 non-nucleoside reverse transcriptase inhibitor, displaying potent efficacy with an EC50 value of 0.01 ?M [1].
价 格:¥电议型 号:T78737产 地:中国大陆
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T78659Crexavibart;化合物 CrexavibartBMS-986413|||C-144-LS;BMS-986413|||C-144-LS
Crexavibart (BMS-986413; C-144-LS), an IgG1 λ2 antibody, specifically targets the receptor-binding domain of the SARS-CoV-2 spike (S) glycoprotein [1].
价 格:¥电议型 号:T78659产 地:中国大陆
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T78657Azilsartan mepixetil potassium;化合物 Azilsartan mepixetil potassiumQR-01019K;QR-01019K
Azilsartan medoxomil potassium (QR-01019K), an angiotensin II receptor antagonist, exhibits a potent and sustained antihypertensive effect, along with a more pronounced and enduring reduction in heart rate, and a high safety profile. It shows promise for investigation in the management of hypertension, chronic heart failure, and diabetic nephropathy[1].
价 格:¥电议型 号:T78657产 地:中国大陆
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T7854Bortezomib-pinanediol;保特佐米蒎烷二醇酯Bortezomib-pinanediol
Bortezomib-pinanediol is a proteasome inhibitor. is a prodrug of Bortezomib.
价 格:¥电议型 号:T7854产 地:中国大陆
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T78538Fisetin quarterhydrate;漆黄素Fisetin quarterhydrate
Fisetin quarterhydrate, a natural flavonol present in numerous fruits and vegetables, exhibits benefits including antioxidant, anticancer, and neuroprotective effects.
价 格:¥电议型 号:T78538产 地:中国大陆
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T7853(+)-Sparteine(+)-鹰爪豆碱鹰爪豆碱|||(+)-鹰爪豆碱|||Pachycarpine
(+)-Sparteine (Pachycarpine) is a natural product extracted from scotch broom, is a sodium channel blocker and a class 1a antiarrhythmic agent
价 格:¥电议型 号:T7853产 地:中国大陆
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T78470β-Aspartylaspartic acid;化合物 β-Aspartylaspartic acidL-β-Aspartyl-L-aspartic acid;L-β-Aspartyl-L-aspar
β-Aspartylaspartic acid, a natural compound, is found in the shoots of Asparagus officinalis [1].
价 格:¥电议型 号:T78470产 地:中国大陆
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T78430Bacterial Sortase Substrate III, Abz/DNP TFA;化合物 Bacterial Sortase Substrate III, Abz/DNP TFABacteri
Bacterial Sortase Substrate III, Abz/DNP TFA is an internally quenched fluorescent peptide used to monitor the activity of the Staphylococcus aureus transpeptidase sortase A (SrtA). This enzyme catalyzes the formation of an amide bond between the carboxyl group of threonine and the amino group of cell-wall crossbridges by cleaving its native substrate, Bacterial Sortase Substrate III, Abz/DNP. The cleavage event can be detected with excitation/emission wavelengths of Ex/Em=320 nm/420 nm.
价 格:¥电议型 号:T78430产 地:中国大陆
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T7839Lasofoxifene Tartrate;酒石酸拉索昔芬CP-336156;CP-336156|||酒石酸拉索昔芬
Lasofoxifene Tartrate (CP-336156) is a third-generation, non-steroidal selective estrogen receptor modulator.
价 格:¥电议型 号:T7839产 地:中国大陆
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T7838Losartan Carboxaldehyde;氯沙坦甲醛Losartan Carboxaldehyde
Losartan Carboxaldehyde is an endothelial cyclooxygenase (COX)-2 inhibitor.
价 格:¥电议型 号:T7838产 地:中国大陆