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T10299AMG PERK 44;化合物 AMG PERK 44AMG PERK 44
AMG PERK 44 is an orally active and selective PERK inhibitor (IC50: 6 nM) that induces autophagy.AMG PERK 44 inhibits GCN2 (IC50: 7300 nM) and B-Raf (IC50 >1000 nM) and can be used in the study of cancer.
价 格:¥电议型 号:T10299产 地:中国大陆
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T10287ALK2-IN-2;化合物ALK2-IN-2ALK2-IN-2
ALK2-IN-2 is a potent and selective inhibitor of activin receptor-like kinase 2 (ALK2) (IC50: 9 nM), inhibiting ALK2 700-fold more than ALK3.
价 格:¥电议型 号:T10287产 地:中国大陆
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T10286ALK/ROS1-IN-1;化合物 T10286ALK/ROS1-IN-1
ALK/ROS1-IN-1 is a potent and selective anti-crizotinib-resistant ALK/ROS1 dual inhibitor (IC50s: 0.530 μM and 0.174 μM for ROS1 and ALK enzyme).
价 格:¥电议型 号:T10286产 地:中国大陆
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T10285ALK inhibitor 1;化合物ALK inhibitor 1ALK inhibitor 1
ALK inhibitor 1 is a selective ALK kinase inhibitor.
价 格:¥电议型 号:T10285产 地:中国大陆
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T10283ALK-IN-5;化合物 T10283ALK-IN-5
ALK-IN-5 is a potent, selective, and brain-penetrant inhibitor of anaplastic lymphoma kinase (ALK, IC50: 2.9 nM).
价 格:¥电议型 号:T10283产 地:中国大陆
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T10282Aliskiren D6 Hydrochloride;化合物 T10282SPP 100 D6 Hydrochloride|||CGP60536B D6 Hydrochloride|||CGP 605
Aliskiren (CGP 60536) D6 Hydrochloride is a deuterium-labeled Aliskiren. Aliskiren hemifumarate is a direct and orally active renin inhibitor (IC50: 1.5 nM).
价 格:¥电议型 号:T10282产 地:中国大陆
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T10276LAKT Kinase Inhibitor HCl;AKT Kinase抑制剂盐酸盐AKT Kinase Inhibitor HCl(842148-40-7 Free base);AKT Kinase
AKT Kinase Inhibitor HCl is an Akt inhibitor with antitumor activity.
价 格:¥电议型 号:T10276L产 地:中国大陆
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T10276AKT Kinase Inhibitor;AKT激酶抑制剂AKT Kinase Inhibitor
AKT Kinase Inhibitor is an Akt inhibitor with antitumor activity that selectively inhibits cell proliferation in a dose-dependent manner.
价 格:¥电议型 号:T10276产 地:中国大陆
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T10275AKT-IN-3;化合物 T10275AKT-IN-3
AKT-IN-3 is a potent, orally active low hERG blocking Akt inhibitor (IC50: 1.4 nM, 1.2 nM, and 1.7 nM for Akt1, Akt2, and Akt3). AKT-IN-3 (compound E22) also exhibits good inhibitory activity against other AGC family kinases, such as PKA, PKC, ROCK1, RSK1, P70S6K, and SGK.
价 格:¥电议型 号:T10275产 地:中国大陆
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T10274AKT-IN-2;化合物 T10274AKT-IN-2
AKT-IN-2 is a selective, and orally bioavailable AKT inhibitor (IC50: 5 nM for AKT1).
价 格:¥电议型 号:T10274产 地:中国大陆
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T1025Tranylcypromine (2-PCPA) hydrochloride反苯环丙胺盐酸盐反苯环丙胺盐酸盐|||Tranylcypromine (2-PCPA) HCl|||SKF-385 HCl
Tranylcypromine (2-PCPA) hydrochloride (SKF-385 HCl), a Monoamine Oxidase inhibitor, is effective in the treatment of major depression, dysthymic disorder, and atypical depression.
价 格:¥电议型 号:T1025产 地:中国大陆
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T1024Roflumilast;罗氟司特B9302-107|||BYK 20869|||APTA 2217|||BY 217;罗氟司特|||B9302-107|||BYK 20869|||APTA 2217|
Roflumilast (APTA 2217) is an orally available, long-acting inhibitor of phosphodiesterase (PDE) type 4 (PDE4), with anti-inflammatory and potential antineoplastic activities. Upon administration, roflumilast and its active metabolite roflumilast N-oxide selectively and competitively bind to and inhibit PDE4, which leads to an increase of both intracellular levels of cyclic-3´, 5´-adenosine monophosphate (cAMP) and cAMP-mediated signaling.
价 格:¥电议型 号:T1024产 地:中国大陆
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T10237ACHP Hydrochloride;化合物ACHP HydrochlorideIKK-2 Inhibitor VIII;IKK-2 Inhibitor VIII
ACHP Hydrochloride (IKK-2 Inhibitor VIII) is a highly potent and selective IKK-β inhibitor with an IC50 of 8.5 nM.
价 格:¥电议型 号:T10237产 地:中国大陆
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T10234Acetylazide;醋磺胺甲氧吡嗪Acetylkelfizina;Acetylkelfizina|||醋磺胺甲氧吡嗪
Acetylazide is a synthetic broad-spectrum bacteriostatic antibiotic.
价 格:¥电议型 号:T10234产 地:中国大陆
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T1023Cefoxitin sodium;头孢西丁钠Cenomycin|||MK-306|||Betacef|||Merxin;Cenomycin|||MK-306|||头孢西丁钠|||Betacef|||M
Cefoxitin sodium (Betacef) is a semisynthetic cephamycin antibiotic resistant to beta-lactamase.
价 格:¥电议型 号:T1023产 地:中国大陆
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T10215AAPK-25;化合物AAPK-25AAPK-25
AAPK-25, a potent and selective dual inhibitor of Aurora/PLK, causes mitotic delay and cell arrest in prometaphase, via phosphorylation of the biomarker histone H3Ser10, followed by a surge in apoptosis. AAPK-25 targets Aurora A, Aurora B, and Aurora C with Kd values ??ranging from 23-289 nM, and PLK1, PLK2, and PLK3 with Kd values ??ranging from 55-456 nM. AAPK-25 has antitumor activity.
价 格:¥电议型 号:T10215产 地:中国大陆
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T1021(R)-Lansoprazole;右旋兰索拉唑Dexlansoprazole|||T 168390|||TAK 390|||R-(+)-Lansoprazole;Dexlansoprazole|||右
(R)-Lansoprazole (T 168390) is the R-isomer of lansoprazole and a substituted benzimidazole prodrug with selective and irreversible proton pump inhibitor activity.Lansoprazole (AG 1749) is a potent brain penetrant neutral sphingomyelinase (N-SMase) inhibitor (exosome inhibitor)
价 格:¥电议型 号:T1021产 地:中国大陆
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T10206A 419259;化合物 T10206RK-20449;RK-20449
A 419259 is a pyrrolo-pyrimidine inhibitor, designed to enhance selectivity towards the Src family (IC50s: 9 nM, <3 nM and <3 nM for Src, Lck and Lyn).
价 格:¥电议型 号:T10206产 地:中国大陆
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T10191L7-Chlorokynurenic acid;7-氯犬尿酸7-chloro-4-hydroxy-2-carboxyquinoline|||7-CKA;7-chloro-4-hydroxy-2-carb
7-Chlorokynurenic acid (7-chloro-4-hydroxy-2-carboxyquinoline) is an effecitve and selective antagonist of NMDA receptor with IC50 of 0.56 μM for the glycine B coagonist site. 7-Chlorokynurenic acid inhibits the reuptake of glutamate into synaptic vesicles with a Ki of 0.59 μM and shows antinociceptive actions after neuraxial delivery.
价 格:¥电议型 号:T10191L产 地:中国大陆
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T101917-Chlorokynurenic acid sodium salt化合物 T101917-CKA sodium salt
7-Chlorokynurenic acid sodium salt (7-CKA sodium salt) is a potent and selective antagonist of the glycine B coagonist site of the NMDA receptor (IC50: 0.56 μM). It is also a potent inhibitor of the reuptake of glutamate into synaptic vesicles (Ki: 0.59 μM).
价 格:¥电议型 号:T10191产 地:中国大陆