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T62356Mardepodect hydrochloride;Mardepodect 盐酸盐PF-2545920 HCl|||Mardepodect HCl|||MP-10 HCl|||PF-02545920
Mardepodect hydrochloride (Mardepodect HCl) is an orally active, selective and potent inhibitor of PDE10A that crosses the blood-brain barrier (IC50: 0.37 nM).Mardepodect hydrochloride up-regulates the expression of proteins encoding specific growth and transcription factors, cell signalling molecules and cell surface proteins. Mardepodect hydrochloride upregulates genes encoding specific growth factors, transcription factors, cell signalling molecules, and cell surface proteins, while downregul
价 格:¥电议型 号:T62356产 地:中国大陆
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T62355HBV-IN-14;化合物 HBV-IN-14HBV-IN-14
HBV-IN-14 is a pyridinopyrimidinone compound and a potent covalent closed-loop DNA (cccDNA) inhibitor. HBV-IN-14 has potential for the study of HBV infection.
价 格:¥电议型 号:T62355产 地:中国大陆
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T62354CDK8-IN-7;化合物 CDK8-IN-7CDK8-IN-7
CDK8-IN-7 (compound 12) is a potent and selective inhibitor of cyclin-dependent kinase 8 (CDK8) (Kd: 3.5 nM). CDK8-IN-7 has shown potential for AML-cancer research.
价 格:¥电议型 号:T62354产 地:中国大陆
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T62353HIV-1 inhibitor-33;化合物 HIV-1 inhibitor-33HIV-1 inhibitor-33
HIV-1 inhibitor-33 (compound 5n) is a potent and selective HIV-1 inhibitor that acts on HIV-1 (EC50: 8.6 nM), MT-4 cells (CC50: 18 μM). HIV-1 inhibitor-33 can be used in the study of AIDS.
价 格:¥电议型 号:T62353产 地:中国大陆
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T62352CXCR4 modulator-2;化合物 CXCR4 modulator-2CXCR4 modulator-2
CXCR4 modulator-2 (compound Z7R) is a potent modulator of CXCR4 (IC50: 1.25 nM). CXCR4 modulator-2 exhibits good stability in mouse serum (t1/2= 77.1 min) and has anti-inflammatory effects in a mouse oedema model.
价 格:¥电议型 号:T62352产 地:中国大陆
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T62351Lotrafiban;化合物 LotrafibanLotrafiban
Lotrafiban is an orally active platelet membrane glycoprotein IIb/IIIa blocker that can be used in the treatment of coronary heart disease and cerebrovascular disease.
价 格:¥电议型 号:T62351产 地:中国大陆
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T62350XO/COX/LOX-IN-1;化合物 XO/COX/LOX-IN-1XO/COX/LOX-IN-1
XO/COX/LOX-IN-1 is a potent inhibitor of xanthine oxidase/cyclooxygenase/lipoxygenase XO/COX/LOX. XO/COX/LOX-IN-1 can be used in the study of inflammatory, cancer and metabolic diseases.
价 格:¥电议型 号:T62350产 地:中国大陆
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T6235Lapatinib Ditosylate;二甲苯磺酸拉帕替尼Lapatinib (GW-572016) Ditosylate|||GW-572016 ditosylate|||Tykerb ditos
Lapatinib Ditosylate (Tykerb ditosylate) is an effective EGFR and ErbB2 inhibitor (IC50: 10.8/9.2 nM for EGFR/ErbB2).
价 格:¥电议型 号:T6235产 地:中国大陆
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T62349Tubulin polymerization-IN-8;化合物 Tubulin polymerization-IN-8Tubulin polymerization-IN-8
Tubulin polymerization-IN-8 (compound IIc) is a potent inhibitor of tubulin polymerization that has been demonstrated to concentration-dependently induce cell cycle arrest at the G2/M phase in HCT116 tumor cells. It also significantly inhibits tubulin polymerization with an IC50 value of 12.7 μM, showing potential for cancer research [1].
价 格:¥电议型 号:T62349产 地:中国大陆
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T62348A1AR antagonist 3;化合物 A1AR antagonist 3A1AR antagonist 3
A1AR antagonist 3 (compound 13) is a selective adenylate 1 (A1) receptor antagonist that acts on human A1 (Ki: 9.69 nM) and rat A1 (Ki: 0.529 nM). A1AR antagonist 3 can be used to study neurological diseases.
价 格:¥电议型 号:T62348产 地:中国大陆
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T62347MPO-IN-5;化合物 MPO-IN-5MPO-IN-5
MPO-IN-5 is a potent, irreversible inhibitor of MPO (myeloperoxidase). MPO-IN-5 inhibits MPO peroxidation (IC50: 0.22 μM) and hERG binding (IC50: 2.8 μM). 23000 M 1s 1.
价 格:¥电议型 号:T62347产 地:中国大陆
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T62346Neuraminidase-IN-7;化合物 Neuraminidase-IN-7Neuraminidase-IN-7
Neuraminidase-IN-7 (compound 4b), a thiophene derivative, is a potent inhibitor of neuraminidase (IC50: 0.03 μM). -Neuraminidase-IN-7 has potential for influenza studies.
价 格:¥电议型 号:T62346产 地:中国大陆
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T62345Neuraminidase-IN-4;化合物 Neuraminidase-IN-4Neuraminidase-IN-4
Neuraminidase-IN-4 (Compound 4b) is a potent inhibitor of neuraminidase (EC50: 1.59 μM). Neuraminidase-IN-4 exhibited significant antiviral activity against A/chicken/Hubei/327/2004 (H5N1-DW).
价 格:¥电议型 号:T62345产 地:中国大陆
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T62344MIF-IN-3;化合物 MIF-IN-3MIF-IN-3
MIF-IN-3 is an inhibitor of migration inhibitory factor (MIF), which can be used in the study of immunoinflammation-related diseases.
价 格:¥电议型 号:T62344产 地:中国大陆
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T62343EGFR-IN-40;化合物 EGFR-IN-40EGFR-IN-40
EGFR-IN-40 (compound 3z) is a potent inhibitor of BTK (IC50: 1.2 nM), EGFR (IC50: 5.3 nM) and ITK (IC50: 46.1 nM).
价 格:¥电议型 号:T62343产 地:中国大陆
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T62342CSF1R-IN-4;化合物 CSF1R-IN-4CSF1R-IN-4
CSF1R-IN-4 is a potent inhibitor of CSF-1R. CSF1R-IN-4 can affect the exchange of inflammatory factors between TAM and glioma cells. CSF1R-IN-4 has potential for the study of cancer diseases. EGFR-IN-40.
价 格:¥电议型 号:T62342产 地:中国大陆
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T62341(R)-Larotrectinib;化合物 (R)-Larotrectinib(R)-Larotrectinib
(R)-Larotrectinib is a potent inhibitor of TRK and acts on TrkA (IC50: 28.5 nM). (R)-Larotrectinib can be used to study cancer, inflammation and certain infectious diseases.
价 格:¥电议型 号:T62341产 地:中国大陆
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T62340NBD-14189;化合物 NBD-14189NBD-14189
NBD-14189 is a potent HIV-1 entry antagonist, acting against HIV-1HXB2 pseudovirus (IC50: 89 nM).NBD-14189 binds HIV-1 gp120 and has a significant antiviral effect (EC50<200 nM).
价 格:¥电议型 号:T62340产 地:中国大陆
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T6234Ambroxol hydrochloride;盐酸氨溴索Mucosolvan|||Mucoangin|||Ambroxol HCl;Mucosolvan|||Mucoangin|||盐酸氨溴索|||A
Ambroxol hydrochloride (Mucosolvan) is a metabolite of BROMHEXINE that stimulates mucociliary action and clears the air passages in the respiratory tract. It is usually administered as the hydrochloride.
价 格:¥电议型 号:T6234产 地:中国大陆
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T62339MsbA-IN-2;化合物 MsbA-IN-2MsbA-IN-2
MsbA-IN-2 is a potent inhibitor of the lipopolysaccharide transporter MsbA and is able to act on E. coli MsbA (IC50: 2 nM).
价 格:¥电议型 号:T62339产 地:中国大陆