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产品数:86101
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T10444TAK1/MAP4K2 inhibitor 1;化合物 T10444TAK1/MAP4K2 inhibitor 1
TAK1/MAP4K2 inhibitor 1 is a potent dual inhibitor of TGFβ-activated kinase 1 (TAK1) and MAP4K2 (IC50s: 41.1 nM and 18.2 nM).
价 格:¥电议型 号:T10444产 地:中国大陆
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T10431Golidocitinib;化合物AZD4205AZD4205;AZD4205
Golidocitinib (AZD4205) is a selective JAK1 inhibitor (IC50: 73 nM) and weakly inhibits JAK2/JAK3 (IC50: >14.7, >30 μM).
价 格:¥电议型 号:T10431产 地:中国大陆
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T10427AZ505 ditrifluoroacetate;化合物 T10427AZ505 ditrifluoroacetate
AZ505 ditrifluoroacetate is an effective and selective SMYD2 inhibitor (IC50: 0.12 μM).
价 格:¥电议型 号:T10427产 地:中国大陆
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T10412Aurora inhibitor 1;化合物 T10412Aurora inhibitor 1
Aurora inhibitor 1 is a potent Aurora inhibitor (IC50: ≤ 4 nM and ≤13 nM for Aurora A and Aurora B kinase).
价 格:¥电议型 号:T10412产 地:中国大陆
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T10409ATX inhibitor 5;ATX抑制剂5ATX inhibitor 5
ATX inhibitor 5 is a potent and orally active autotaxin (ATX) inhibitor (IC50 : 15.3 nM) that reduces the level of CCl4-induced hepatic fibrosis and has anti-hepatic fibrosis effects,.
价 格:¥电议型 号:T10409产 地:中国大陆
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T10407Gartisertib;化合物 T10407ATR inhibitor 2;ATR inhibitor 2
ATR inhibitor 2 is an orally active, ATP-competitive, and selective ATR inhibitor (Ki <150 pM) with antitumor activity. ATR inhibitor 2 potently inhibits ATR-driven phosphorylated checkpoint kinase-1 (Chk1) phosphorylation (IC50: 8 nM).
价 格:¥电议型 号:T10407产 地:中国大陆
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T10406Tuvusertib;化合物TuvusertibM1774|||ATR inhibitor 1;M1774|||ATR inhibitor 1
Tuvusertib (M1774) is an orally available ataxia telangiectasia and Rad3-related (ATR) kinase inhibitor (Ki< 1 ?Μ) with selective and potentially antitumor activity.Tuvusertib selectively inhibits ATR activity and blocks downstream phosphorylation of serine/threonine protein kinase checkpoint kinase 1 (CHK1), thereby inhibits DNA damage checkpoint activation, disrupting DNA damage repair and inducing apoptosis in tumor cells.
价 格:¥电议型 号:T10406产 地:中国大陆
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T10404ATP synthase inhibitor 1;化合物ATP synthase inhibitor 1ATP synthase inhibitor 1
ATP synthase inhibitor 1 is an inhibitor of the c subunit of the F1/FO-ATP synthase complex. It inhibits mitochondrial permeability transition pore (mPTP) opening and does not affect ATP levels.
价 格:¥电议型 号:T10404产 地:中国大陆
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T10402Atorvastatin Epoxy Tetrahydrofuran Impurity;化合物 T10402Atorvastatin Epoxy Tetrahydrofuran Impurity
Atorvastatin Epoxy Tetrahydrofuran Impurity is an impurity isolated oxidative degradation products of Atorvastatin. Atorvastatin is an orally active HMG-CoA reductase inhibitor.
价 格:¥电议型 号:T10402产 地:中国大陆
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T1040Vitamin B12;维生素B12Cyanocobalamin|||Cobalamin;Cyanocobalamin|||Cobalamin|||维生素B12
Cyanocobalamin is a cobalt-containing coordination compound generated by intestinal microbes and a natural water-soluble vitamin of the B-complex family that must combine with Intrinsic Factor for absorption by the intestine. Cyanocobalamin is necessary for hematopoiesis, neural metabolism, DNA, and RNA production, and carbohydrate, fat, and protein metabolism. B12 improves iron functions in the metabolic cycle and assists folic acid in choline synthesis. B12 metabolism is interconnected with th
价 格:¥电议型 号:T1040产 地:中国大陆
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T10396ATM Inhibitor-1;化合物 T10396ATM Inhibitor-1
ATM Inhibitor-1 is a highly potent, selective and orally active ATM inhibito (IC50: 0.7 nM) anti-tumor activity. It shows weak activity against mTOR (IC50, 21 μM), DNAPK (IC50, 2.8 μM), PI3Kα (IC50, 3.8 μM), PI3Kβ (IC50, 10.3 μM), PI3Kγ (IC50, 3 μM) and PI3Kδ (IC50, 0.73 μM).
价 格:¥电议型 号:T10396产 地:中国大陆
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T10367Arginase inhibitor 1;化合物 T10367Arginase inhibitor 1
Arginase inhibitor 1 is a potent inhibitor of human arginases I and II (IC50s: 223 and 509 nM).
价 格:¥电议型 号:T10367产 地:中国大陆
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T10358LAR-13324 M1 metabolite;化合物 T10358LAR-13324 M1 metabolite
AR-13324 M1 metabolite is a hydrolysis metabolite of AR-13324 mesylate.
价 格:¥电议型 号:T10358L产 地:中国大陆
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T10351Aprocitentan D4;化合物 T10351ACT-132577 D4;ACT-132577 D4
Aprocitentan D4 (ACT-132577 D4) is a deuterium-labeled Aprocitentan. Aprocitentan is a major and pharmacologically active metabolite of Macitentan. Aprocitentan is a dual ETA/ETB antagonist (IC50s: 3.4 nM and 987 nM; pA2s: 6.7 and 5.5).
价 格:¥电议型 号:T10351产 地:中国大陆
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T10342Antitumor agent-2;抗肿瘤剂2Antitumor agent-2
Antitumor agent-2 has anti-inflammatory and anti-tumor activity and can be used to study cancer.
价 格:¥电议型 号:T10342产 地:中国大陆
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T10341Antitumor agent-19;化合物Antitumor agent-19Antitumor agent-19
Antitumor agent-19 is a modulator of tumor-associated macrophages with EC50s of 17.18 μM and 18.87 μM in the RAW 264.7 cells and the BMDM cells.
价 格:¥电议型 号:T10341产 地:中国大陆
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T10340Antitrypanosomal agent 2;抗锥体虫剂2Antitrypanosomal agent 2
Antitrypanosomal agent 2 shows potent and specific antiparasite activities against Trypanosoma brucei.
价 格:¥电议型 号:T10340产 地:中国大陆
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T10339Antitrypanosomal agent 1;1-(3,4-二氯苯基)-3-(二甲基氨基)丙-1-酮盐酸盐Antitrypanosomal agent 1
Antitrypanosomal agent 1 is a potent and selective trypanothione reductase (TR) inhibitor (IC50: 3.3 μM). Antitrypanosomal agent 1 inhibits glutathione reductase (IC50: 64.8 μM) and T. brucei (EC50: 1 μM).
价 格:¥电议型 号:T10339产 地:中国大陆
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T10328Anti-parasitic agent 3;化合物 T10328Anti-parasitic agent 3
Anti-parasitic agent 3 is an anti-parasitic agent active against drug-resistant parasites.
价 格:¥电议型 号:T10328产 地:中国大陆
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T10318Anatabine dicitrate;化合物 T10318Anatabine dicitrate
Anatabine dicitrate is a tobacco alkaloid that can cross the blood-brain barrier. It is a potent α4β2 nAChR agonist and inhibits NF-κB activation lower amyloid-β (Aβ) production by preventing the β-cleavage of the amyloid precursor protein.
价 格:¥电议型 号:T10318产 地:中国大陆