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T74510TFMU-ADPr;化合物 TFMU-ADPrTFMU-ADPr
TFMU-ADPr serves as a versatile substrate for assessing poly(ADP-ribose) glycohydrolase (PARG) activity, enabling direct measurement of total PAR hydrolase activity through the liberation of a fluorophore. Exhibiting exceptional reactivity, generality, stability, and usability, TFMU-ADPr is an effective tool for evaluating small-molecule inhibitors and investigating the regulation of ADP-ribosyl catabolic enzymes in vitro [1].
价 格:¥电议型 号:T74510产 地:中国大陆
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T74427Paridiprubart;化合物 ParidiprubartParidiprubart
Paridiprubart (NI-0101), a humanized monoclonal antibody targeting TLR4, offers promising research avenues for rheumatoid arthritis [1].
价 格:¥电议型 号:T74427产 地:中国大陆
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T74426Ogalvibart;化合物 OgalvibartOgalvibart
Ogalvibart (C-135-LS), a humanized anti-SARS-CoV-2 IgG1 type monoclonal antibody, specifically targets and binds to the spike (S) glycoprotein receptor-binding domain (RBD) of the SARS-CoV-2 virus. When combined with C144LS in a 1:1 ratio, Ogalvibart demonstrates significant preventive activity and effectively prevents the progression of COVID-19 in a rhesus monkey disease model [1].
价 格:¥电议型 号:T74426产 地:中国大陆
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T74425Nepuvibart;化合物 NepuvibartNepuvibart
Nepuvibart (ZRC3308-B10), an IgG1 type anti-SARS-CoV-2 monoclonal antibody, exhibits strong binding affinity to a distinct non-competing epitope on the receptor-binding domain (RBD) of the SARS-CoV-2 spike protein. When combined in a 1:1 ratio with ZRC3308-A7, Nepuvibart is effective in preventing COVID-19 and in treating the early stages of the disease before it progresses to severe illness [1].
价 格:¥电议型 号:T74425产 地:中国大陆
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T74424Masavibart;化合物 MasavibartMasavibart
Masavibart (ZRC3308-A7), an IgG1 type anti-SARS-CoV-2 monoclonal antibody, demonstrates strong binding affinity for a distinct non-competing epitope located on the receptor-binding domain (RBD) of the SARS-CoV-2 spike protein. When paired in a 1:1 ratio with ZRC3308-B10, Masavibart is efficacious in preventing COVID-19, particularly in its early stages before the onset of severe symptoms [1].
价 格:¥电议型 号:T74424产 地:中国大陆
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T74191Tanshinol borneol ester;化合物 Tanshinol borneol esterTanshinol borneol ester
Tanshinol borneol ester, an angiogenesis stimulator, enhances several critical phases of angiogenesis via the Akt and MAPK signaling pathways. This compound also exhibits anti-ischemic and anti-atherosclerosis properties [1].
价 格:¥电议型 号:T74191产 地:中国大陆
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T74116Glucocorticoid receptor agonist-1 Ala-Ala-Mal;化合物 Glucocorticoid receptor agonist-1 Ala-Ala-MalGluco
Glucocorticoid receptor agonist-1 Ala-Ala-Mal (compound 88), a glucocorticosteroid and glucocorticoid receptor agonist, can be conjugated with Adalimumab to formulate an ADC [1].
价 格:¥电议型 号:T74116产 地:中国大陆
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T74089Mifamurtide TFA;化合物 Mifamurtide TFAMifamurtide TFA
Mifamurtide TFA (MTP-PE TFA), a muramyl dipeptide (MDP) analog, acts as a nonspecific immunomodulator by activating macrophages and monocytes to stimulate the immune response. As an orphan agent and a specific NOD2 ligand, it is utilized as an insulin sensitizer and holds research potential in osteosarcoma [1] [2] [3].
价 格:¥电议型 号:T74089产 地:中国大陆
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T74031Cardiolipin (Heart, Bovine) (sodium);化合物 Cardiolipin (Heart, Bovine) (sodium)Cardiolipin (Heart, Bov
Cardiolipin (Heart, Bovine) Sodium, a phospholipid exclusive to mitochondria, shows potential for neurological disease research [1].
价 格:¥电议型 号:T74031产 地:中国大陆
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T74016Trityl olmesartan medoxomil impurity III;化合物 Trityl olmesartan medoxomil impurity IIITrityl olmesart
Trityl olmesartan medoxomil impurity III is a specific impurity found in trityl olmesartan medoxomil, which serves as an intermediate in the synthesis of Olmesartan medoxomil [1].
价 格:¥电议型 号:T74016产 地:中国大陆
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T73974Olmesartan ethyl ester;化合物 Olmesartan ethyl esterOlmesartan ethyl ester
Olmesartan ethyl ester (compound 11), an impurity of Olmesartan (RNH-6270), functions as an antagonist to the angiotensin II receptor (AT1R), primarily utilized in studies related to high blood pressure [1].
价 格:¥电议型 号:T73974产 地:中国大陆
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T73914Eremofortin A;化合物 Eremofortin AEremofortin A
Eremofortin A, a metabolite, can be isolated from Penicillium roqueforti cultures [1].
价 格:¥电议型 号:T73914产 地:中国大陆
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T73862Almurtide;化合物 AlmurtideAlmurtide
Almurtide (nor-MDP), a derivative of muramyl dipeptide, exhibits anti-inflammatory and anti-tumor properties. It demonstrates protective effects in mice against infections caused by Pseudomonas aeruginosa when administered intraperitoneally and Candida albicans when administered intravenously. Furthermore, Almurtide has been shown to inhibit the carcinogenic Friend leukemia virus [1] [2] [3].
价 格:¥电议型 号:T73862产 地:中国大陆
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T73844Nortriptyline;化合物 NortriptylineNortriptyline
Nortriptyline (Desmethylamitriptyline), the primary active metabolite of Amitriptyline, functions as a tricyclic antidepressant, effectively alleviating symptoms of depression. It is also recognized as a potent autophagy inhibitor [1] [2].
价 格:¥电议型 号:T73844产 地:中国大陆
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T7384Ocifisertib(CFI-400945 free base);化合物Ocifisertib(CFI-400945 free base)Ocifisertib(CFI-400945 free ba
CFI-400945 is an potent, selective and orally active inhibitor of polo-like kinase 4(PLK4; Ki value of 0.26 nM).
价 格:¥电议型 号:T7384产 地:中国大陆
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T7379418-Hydroxycortisol;化合物 18-Hydroxycortisol18-Hydroxycortisol
18-Hydroxycortisol, a cortisol derivative and steroidogenic intermediate, is an endogenous steroid secreted by the adrenal cortex. It serves as a useful biochemical marker in primary aldosteronism (PA) research [1].
价 格:¥电议型 号:T73794产 地:中国大陆
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T73713Flupirtine-d4 hydrochloride;化合物 Flupirtine-d4 hydrochlorideFlupirtine-d4 hydrochloride
Flupirtine-d4 (D 9998-d4) hydrochloride, the deuterium-labeled version of Flupirtine (D 9998) hydrochloride, is a selective neuronal potassium channel opener with additional NMDA receptor antagonist properties [1] [2].
价 格:¥电议型 号:T73713产 地:中国大陆
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T7369LGemigliptin Tartrate(911637-19-9 free base);吉格列汀酒石酸盐LC15-0444 tartrate;吉格列汀酒石酸盐|||LC15-0444 tartrate
Gemigliptin Tartrate (LC15-0444 tartrate) is a highly selective, reversible and competitive inhibitor of dipeptidyl peptidase-4 (DPP-4). It has an IC50 of 10.3 nM for human recombinant DPP-4. Gemigliptin tartrate exhibits potent anti-glycation properties.
价 格:¥电议型 号:T7369L产 地:中国大陆
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T73664Adrenocorticotropic hormone TFA;化合物 Adrenocorticotropic hormone TFAAdrenocorticotropic hormone TFA
Adrenocorticotropic hormone (ACTH) TFA, a polypeptide tropic hormone synthesized by the anterior pituitary gland, regulates the production of cortisol and androgens [1] [2].
价 格:¥电议型 号:T73664产 地:中国大陆
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T73663Adrenocorticotropic hormone;化合物 Adrenocorticotropic hormoneAdrenocorticotropic hormone
Adrenocorticotropic hormone (ACTH), a polypeptide tropic hormone secreted by the anterior pituitary gland, regulates cortisol and androgen production [1] [2].
价 格:¥电议型 号:T73663产 地:中国大陆