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T10684LCarnostatine hydrochloride;化合物 T10684LSAN9812 hydrochloride;SAN9812 hydrochloride
Carnostatine hydrochloride (SAN9812 hydrochloride) is a potent, selective inhibitor of carnosinase 1 (CN1), exhibiting a K_i of 11 nM against human recombinant CN1. This compound shows promise for the treatment of diabetic nephropathy (DN) [1].
价 格:¥电议型 号:T10684L产 地:中国大陆
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T10684Carnostatine;化合物 T10684SAN9812;SAN9812
Carnostatine (SAN9812) is a potent and selective carnosinase 1 ( CN1 ) inhibitor with a K i of 11 nM for human recombinant CN1. Carnostatine may be used to increase renal carnosine concentration as a potential therapeutic modality for diabetic nephropathy (DN). [1].
价 格:¥电议型 号:T10684产 地:中国大陆
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T10625L(Rac)-IBT6A hydrochloride (1412418-47-3 free base);化合物 T10625L(Rac)-IBT6A hydrochloride;(Rac)-IBT6A
(Rac)-IBT6A hydrochloride is a racemate of IBT6A. IBT6A is an impurity of Ibrutinib. IBT6A can be used in the synthesis of IBT6A Ibrutinib dimer and IBT6A adduct. Ibrutinib is a Btk inhibitor (IC50: 0.5 nM).
价 格:¥电议型 号:T10625L产 地:中国大陆
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T10612Brexpiprazole S-oxide;化合物 T10612DM-3411;DM-3411
Brexpiprazole S-oxide (DM-3411) is a main metabolite of Brexpiprazole. Brexpiprazole is a partial agonist of human 5-HT1A and dopamine receptors (Kis: 0.12 nM and 0.3 nM).
价 格:¥电议型 号:T10612产 地:中国大陆
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T10610Brexpiprazole-d8;化合物 T10610OPC-34712 D8;OPC-34712 D8
Brexpiprazole D8 (OPC-34712 D8) is a deuterium-labeled Brexpiprazole. Brexpiprazole is a partial agonist of human 5-HT1A and dopamine receptors (Ki: 0.12 nM and 0.3 nM).
价 格:¥电议型 号:T10610产 地:中国大陆
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T10581Boc-MLF TFA (67247-12-5 free base);化合物 T10581Boc-Met-Leu-Phe-OH (TFA)|||Boc-MLF TFA;Boc-Met-Leu-Phe-
Boc-MLF (TFA) is a specific antagonist of formyl peptide receptor (FPR) and also inhibits signaling through FPRL1 at higher concentrations.
价 格:¥电议型 号:T10581产 地:中国大陆
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T1058Carboplatin;卡铂NSC 241240|||CBDCA|||JM-8;NSC 241240|||卡铂|||CBDCA|||JM-8
Carboplatin (JM-8) is a cisplatin derivative, a DNA synthesis inhibitor. Carboplatin binds to DNA, inhibits replication and transcription, and induces cell death. Carboplatin has antitumor activity.
价 格:¥电议型 号:T1058产 地:中国大陆
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T10572LBMT-124110 Formate;BMT-124110甲酸盐BMT-124110 Formate(1679371-59-5 Free base);BMT-124110 Formate(167937
BMT-124110 Formate is a selective AAK1 inhibitor (IC50: 0.9 nM) with anti-injury sensory activity.BMT-124110 Formate inhibits the BMP-2-inducible protein kinase BIKE with an IC50: 17 nM.BMT-124110 Formate inhibits the cell-cycle protein G-related BMT-124110 Formate inhibits the cell cycle protein G-associated kinase GAK with an IC50:99 nM.
价 格:¥电议型 号:T10572L产 地:中国大陆
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T10572BMT-124110;化合物BMT-124110BMT-124110
BMT-124110 is a selective AAK1 inhibitor (IC50: 0.9 nM) with antinociceptive activity. BMT-090605 inhibited BMP-2 induced protein kinase BIKE with IC50 of 17 nM. BMT-090605 inhibits cyclin G-associated kinase GAK with an IC50 of 99 nM.
价 格:¥电议型 号:T10572产 地:中国大陆
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T10562(4-Acetamidocyclohexyl) nitrate;化合物 T10562BM121307;BM121307
(4-Acetamidocyclohexyl) nitrate (BM121307) is an activator of guanylate cyclase.
价 格:¥电议型 号:T10562产 地:中国大陆
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T10561BM-131246;化合物BM-131246BM-131246
BM-131246 is an orally available and antidiabetic active thiazolidinedione derivative for the study of diabetes.
价 格:¥电议型 号:T10561产 地:中国大陆
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T10512Prenyl-IN-1;Prenyl抑制剂1Prenyl-IN-1
Prenyl-IN-1 is a potent and selective prenylation inhibitor of geranylgeranyltransferase or farnesyltransferase.Prenyl-IN-1 shows anti-oxidative stress effects in a Parkinson´s model. Prenyl-IN-1 showed anti-oxidative stress in a Parkinson´s model.
价 格:¥电议型 号:T10512产 地:中国大陆
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T1050Prazosin hydrochloride哌唑嗪盐酸盐Prazosin hydrochloride|||哌唑嗪盐酸盐|||Prazosin HCl|||cp-12299-1|||Peripress|
Prazosin hydrochloride (Vasoflex) reduces peripheral resistance and relaxes vascular smooth muscles as a selective adrenergic alpha-1 antagonist by a mechanism not completely known. Prazosin hydrochloride is a synthetic piperazine derivative with hypotensive antiadrenergic properties, It is used in the treatment of heart failure, hypertension, pheochromocytoma, Raynaud´s syndrome, prostatic hypertrophy, and urinary retention.
价 格:¥电议型 号:T1050产 地:中国大陆
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T10495LBefiradol化合物 T10495LNLX-112|||F13640
Befiradol (NLX-112) is an agonist of 5-HT1A receptor.
价 格:¥电议型 号:T10495L产 地:中国大陆
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T10458Banoxantrone (D12);化合物 T10458Banoxantrone (D12)|||Banoxantrone D12|||Banoxantrone (D-12)|||Banoxantr
Banoxantrone D12 (AQ4N D12) is the deuterium-labeled Banoxantrone. Banoxantrone is a bioreductive agent that can be reduced to a stable, DNA-affinity compound AQ4, which is a topoisomerase II inhibitor.
价 格:¥电议型 号:T10458产 地:中国大陆
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T1044Clopidol;氯羟吡啶WR-61112;氯吡多|||氯羟吡啶|||WR-61112
Clopidol (WR-61112) is a very effective anticoccidial agent used in poultry.
价 格:¥电议型 号:T1044产 地:中国大陆
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T10426AZ12601011;化合物 T10426AZ12601011
AZ12601011 is a highly potent and selective inhibitor of the TGFBR1 kinase, administered orally. It displays an IC50 of 18 nM and a Kd of 2.9 nM. By selectively targeting ALK4, TGFBR1, and ALK7, AZ12601011 effectively inhibits the phosphorylation of SMAD2. Additionally, it has been shown to hinder the growth and metastasis of mammary tumors [1].
价 格:¥电议型 号:T10426产 地:中国大陆
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T10419AV-412;化合物AV-412MP412;MP412
AV-412 (MP412) is an EGFR inhibitor (EGFR, EGFR T790M, EGFR L858R, EGFR L858R/T790M and ErbB2 with IC50s of 0.75, 0.79, 0.5, 2.3, 19 nM).
价 格:¥电议型 号:T10419产 地:中国大陆
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T10412Aurora inhibitor 1;化合物 T10412Aurora inhibitor 1
Aurora inhibitor 1 is a potent Aurora inhibitor (IC50: ≤ 4 nM and ≤13 nM for Aurora A and Aurora B kinase).
价 格:¥电议型 号:T10412产 地:中国大陆
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T10411AU1235;化合物AU1235AU1235
AU1235 is a Mycobacterium tuberculosis inhibitor.
价 格:¥电议型 号:T10411产 地:中国大陆