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T10431Golidocitinib;化合物AZD4205AZD4205;AZD4205
Golidocitinib (AZD4205) is a selective JAK1 inhibitor (IC50: 73 nM) and weakly inhibits JAK2/JAK3 (IC50: >14.7, >30 μM).
价 格:¥电议型 号:T10431产 地:中国大陆
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T10430AZD 2066;化合物 T10430AZD 2066
AZD 2066 is a selective, orally active, and brain-penetrant mGluR5 antagonist with analgesic activity.
价 格:¥电议型 号:T10430产 地:中国大陆
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T10429Tizaterkib;化合物AZD-0364AZD-0364;AZD-0364
Tizaterkib (AZD-0364) is a potent and selective ERK2 inhibitor.
价 格:¥电议型 号:T10429产 地:中国大陆
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T10428AZ82;化合物 T10428AZ82
AZ82 is a selective kinesin-like protein KIFC1 (HSET/KIFC1) inhibitor (Ki: 43 nM; IC50: 300 nM for KIFC1).
价 格:¥电议型 号:T10428产 地:中国大陆
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T10427AZ505 ditrifluoroacetate;化合物 T10427AZ505 ditrifluoroacetate
AZ505 ditrifluoroacetate is an effective and selective SMYD2 inhibitor (IC50: 0.12 μM).
价 格:¥电议型 号:T10427产 地:中国大陆
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T10426AZ12601011;化合物 T10426AZ12601011
AZ12601011 is a highly potent and selective inhibitor of the TGFBR1 kinase, administered orally. It displays an IC50 of 18 nM and a Kd of 2.9 nM. By selectively targeting ALK4, TGFBR1, and ALK7, AZ12601011 effectively inhibits the phosphorylation of SMAD2. Additionally, it has been shown to hinder the growth and metastasis of mammary tumors [1].
价 格:¥电议型 号:T10426产 地:中国大陆
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T10425AZ084;化合物AZ084AZ084
AZ084 is a potent, selective, allosteric, and oral active CCR8 antagonist (Ki: 0.9 nM). It has the potential to treat asthma.
价 格:¥电议型 号:T10425产 地:中国大陆
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T10424AZ-3;化合物 T10424AZ-3
AZ-3 is a potent and selective JAK1 inhibitor (IC50: 34 nM).
价 格:¥电议型 号:T10424产 地:中国大陆
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T10423AWZ1066S;化合物AWZ1066SAWZ1066S
AWZ1066S is a highly specific anti-Wolbachia drug candidate for the short-course treatment of filariasis (EC50: 2.5 nM in cell assay).
价 格:¥电议型 号:T10423产 地:中国大陆
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T10389LAspartyl-alanyl-diketopiperazine acetate;化合物T10389LDA-DKP|||Aspartyl-alanyl-diketopiperazine acetate
Aspartyl-alanyl-diketopiperazine acetate (DA-DKP) (DA-DKP) can modulate the inflammatory immune response through a molecular pathway implicated in T- lymphocyte anergy.
价 格:¥电议型 号:T10389L产 地:中国大陆
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T10389Aspartyl-alanyl-diketopiperazine;化合物AmpionDA-DKP;DA-DKP
Aspartyl-alanyl-diketopiperazine (DA-DKP) is a known immunomodulatory molecule from the N terminus of human albumin.
价 格:¥电议型 号:T10389产 地:中国大陆
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T10379Arzoxifene hydrochloride;化合物 T10379SERM 3|||LY 353381 HCl;SERM 3|||LY 353381 HCl
Arzoxifene hydrochloride is a selective estrogen receptor modulator that is a potent estrogen antagonist in mammary and uterine tissue.
价 格:¥电议型 号:T10379产 地:中国大陆
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T10377Artefenomel;化合物 T10377OZ439;OZ439
Artefenomel (OZ439) is a synthetic antimalarial agent with the artemisinin pharmacophore.
价 格:¥电议型 号:T10377产 地:中国大陆
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T10368Aripiprazole (D8);化合物 T10368OPC-14597u00A0D8;OPC-14597u00A0D8
Aripiprazole D8 (OPC-14597 D8) is the deuterium-labeled Aripiprazole. Aripiprazole is a human 5-HT1A receptor partial agonist (Ki: 4.2 nM).
价 格:¥电议型 号:T10368产 地:中国大陆
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T10363Arazine;化合物ArazineN-Acetyl-S-farnesyl-L-cysteine;N-Acetyl-S-farnesyl-L-cysteine
Arazine (N-Acetyl-S-farnesyl-L-cysteine) can be a a substrate for isoprenylcysteine methyltransferase by competing with prenylated G protein or its receptors site. Arazine is a cell-permeable modulator of G protein and GPCR signaling.
价 格:¥电议型 号:T10363产 地:中国大陆
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T10304Aminochlorthenoxazin;化合物 T10304ICI 350;ICI 350
Aminochlorthenoxazin is an antipyretic and analgesic agent.
价 格:¥电议型 号:T10304产 地:中国大陆
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T1029Aztreonam;氨曲南SQ-26,776;SQ-26,776|||氨曲南
Aztreonam (SQ-26,776) is a monocyclic beta-lactam antibiotic originally isolated from Chromobacterium violaceum with bactericidal activity.
价 格:¥电议型 号:T1029产 地:中国大陆
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T10289Alosetron ((Z)-2-butenedioate);马来酸阿洛司琼GR 68755 ((Z)-2-butenedioate)|||GR 68755X ((Z)-2-butenedioate)
Alosetron (GR 68755) (Z)-2-butenedioate is a Serotonin 5HT3-receptor antagonist that is used in the treatment of irritable bowel syndrome.
价 格:¥电议型 号:T10289产 地:中国大陆
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T10281Alimemazine;化合物 T10281Trimeprazine;Trimeprazine
Alimemazine (Trimeprazine) is generally used as an antipruritic agent and also a hemagglutinin (HA)-receptor antagonist. Alimemazine also acts as a partial agonist against the histamine H1 receptor (H1R) and other GPCRs.
价 格:¥电议型 号:T10281产 地:中国大陆
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T10280Alimemazine D6;化合物 T10280Trimeprazine D6;Trimeprazine D6
Alimemazine D6 is a deuterium-labeled Alimemazine. Alimemazine is an antihistamine.
价 格:¥电议型 号:T10280产 地:中国大陆