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T11221ERAP1-IN-1;化合物ERAP1-IN-1ERAP1-IN-1
ERAP1-IN-1 is an endoplasmic reticulum aminopeptidase 1 (ERAP1) inhibitor. ERAP1-IN-1 allosterically activates ERAP1’s hydrolysis of fluorogenic and chromogenic amino acid substrates but competitively inhibits its activity toward a nonamer peptide representative of physiological substrates.
价 格:¥电议型 号:T11221产 地:中国大陆
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T11220ER21355;化合物 T11220ER21355
ER21355, utilized for the treatment of prostatic diseases, acts as a phosphodiesterase 5 (PDE5) inhibitor.
价 格:¥电议型 号:T11220产 地:中国大陆
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T11218ε-?Viniferin;Epsilon-白藜芦醇脱氢二聚体epsilon-Viniferin;epsilon-Viniferin|||Epsilon-白藜芦醇脱氢二聚体
ε-?Viniferin (epsilon-Viniferin) a dimer of resveratrol, shows the inhibitory effects of epsilon-viniferin on human CYP1A1, CYP1A2, CYP1B1, CYP2A6, CYP2B6, CYP2E1, CYP3A4 and CYP4A activities.
价 格:¥电议型 号:T11218产 地:中国大陆
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T11217Eplivanserin;依利色林SR-46349;依利色林|||SR-46349
Eplivanserin (SR-46349) is an effective and selective antagonist of 5-HT2A receptor with a Kd of 1.14 nM and an IC50 value of 5.8 nM in rat cortical membrane.
价 格:¥电议型 号:T11217产 地:中国大陆
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T11216Eplivanserin (mixture)化合物 T11216Eplivanserin mixture|||SR-46349 (mixture)
Eplivanserin mixture is a selective serotonin reuptake inhibitor and a 5-HT2A receptor antagonist,
价 格:¥电议型 号:T11216产 地:中国大陆
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T11213LEpertinib;化合物 T11213LS-22611;S-22611
Epertinib is a reversible and selective tyrosine kinase inhibitor of EGFR, HER2, and HER4 (IC50s: 1.48 nM, 7.15 nM, and 2.49 nM). It displays a strong antitumor activity.
价 格:¥电议型 号:T11213L产 地:中国大陆
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T11213Epertinib hydrochloride;化合物Epertinib hydrochlorideS-22611 hydrochloride;S-22611 hydrochloride
Epertinib hydrochloride (S-22611 hydrochloride) shows potent antitumor activity. Epertinib hydrochloride is a potent, orally active, reversible, and selective tyrosine kinase inhibitor of EGFR, HER2 and HER4, with IC50s of 1.48 nM, 7.15 nM and 2.49 nM, respectively.
价 格:¥电议型 号:T11213产 地:中国大陆
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T11200Endoxifen (E-isomer);N-去甲-4-羟基-三苯氧胺E-Endoxifen|||Endoxifen E-isomer;N-去甲-4-羟基-三苯氧胺|||E-Endoxifen|||E
Endoxifen E-isomer (E-Endoxifen) is the E-isomer of (Z)-Endoxifen. Endoxifen E-isomer has antiestrogenic effects.
价 格:¥电议型 号:T11200产 地:中国大陆
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T11195Enantiomer of Sofosbuvir;化合物 T11195Enantiomer of Sofosbuvir
Sofosbuvir´s enantiomer, a variant of the prescription medication Sofosbuvir used for chronic hepatitis C treatment, currently lacks reported biological activity.
价 格:¥电议型 号:T11195产 地:中国大陆
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T11173LElacestrant S enantiomer dihydrochloride;化合物 T11173LRAD1901 S enantiomer dihydrochloride|||RAD-1901
Elacestrant (RAD1901) dihydrochloride is a selective and orally available estrogen receptor (ERR) degrader with IC50 values of 48 and 870 nM for ERα and ERβ, respectively. Elacestrant S enantiomer dihydrochloride is an low activity enantiomer of elacestrant dihydrochloride.
价 格:¥电议型 号:T11173L产 地:中国大陆
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T11173Elacestrant S enantiomer;化合物 T11173RAD1901 S enantiomer;RAD1901 S enantiomer
Elacestrant S enantiomer is a selective and orally available estrogen receptor (ERR) degrader with IC50 values of 48 and 870 nM for ERα and ERβ, respectively.
价 格:¥电议型 号:T11173产 地:中国大陆
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T11160EGFR-IN-5;化合物EGFR-IN-5EGFR-IN-5|||inhibit|||Epidermal growth factor receptor|||HER1|||ErbB-1|||Inhib
EGFR-IN-5 is a selective inhibitor of EGFR. The IC50s for EGFR, EGFR(L858R), EGFR(L858R/T790M), and EGFR(L858R/T790M/C797S) are 10.4, 1.1, 34, 7.2 nM, respectively.
价 格:¥电议型 号:T11160产 地:中国大陆
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T11156Nazartinib S-enantiomer;化合物 T11156EGF816 (S-enantiomer);EGF816 (S-enantiomer)
Nazartinib is an EGFR inhibitor. Nazartinib S-enantiomer is the less active S-enantiomer of Nazartinib.
价 格:¥电议型 号:T11156产 地:中国大陆
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T11129LDuvelisib (R enantiomer) hydrochloride;杜韦利西布R对映体盐酸盐IPI-145 R enantiomer HCl|||Duvelisib (R enantiome
Duvelisib (R enantiomer) hydrochloride (INK1197 R enantiomer HCl) is a PI3K inhibitor. Duvelisib (R enantiomer) hydrochloride is the less active enantiomer of Duvelisib.
价 格:¥电议型 号:T11129L产 地:中国大陆
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T11129Duvelisib (R enantiomer)化合物Duvelisib R entiomerDuvelisib R enantiomer|||IPI-145 R enantiomer|||INK11
Duvelisib R enantiomer (IPI-145 R enantiomer) is an enantiomer of Duvelisib with lower activity. Duvelisib is a PI3K inhibitor.
价 格:¥电议型 号:T11129产 地:中国大陆
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T11121Duoperone;度奥哌隆Duoperone
Duoperone is a neuroleptic agent. Duoperone shows antiemetic activity in animal models.
价 格:¥电议型 号:T11121产 地:中国大陆
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T11089Doxercalciferol-D3;化合物 T11089Doxercalciferol-D3
Doxercalciferol-d3 is the deuterated form of Doxercalciferol and ACTS as vitamin D receptor activator (VDRA), which is a vitamin D2 analogue.
价 格:¥电议型 号:T11089产 地:中国大陆
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T11074Dolutegravir intermediate-1;化合物Dolutegravir intermediate-11-(2,2-dimethoxyethyl)-5-methoxy-6-methoxy
Dolutegravir intermediate-1 (1-(2,2-dimethoxyethyl)-5-methoxy-6-(methoxycarbonyl)-4-oxo-1,4-dihydropyridine-3-carboxylic acid) is a new synthetic Dolutegravir intermediate. Dolutegravir is an integrase inhibitor developed for the treatment of human immunodeficiency virus (HIV)-1 infection.
价 格:¥电议型 号:T11074产 地:中国大陆
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T11064DMT1 blocker 2;化合物DMT1 blocker 2DMT1 blocker 2
DMT1 blocker 2, compound 12f, is a direct inhibitor of divalent metal transporter 1 (DMT1) with an IC50 hydrogen peroxide value of 0.83, which is expected to block iron uptake by intestinal epithelial cells in vivo.
价 格:¥电议型 号:T11064产 地:中国大陆
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T11063DMT1 blocker 1;化合物DMT1 blocker 1DMT1 blocker 1
DMT1 blocker 1 is a blocker of divalent metal transporter 1 (DMT1) with IC50 of 0.64 μM, which is expected to block the absorption of iron by intestinal cells in vivo.
价 格:¥电议型 号:T11063产 地:中国大陆