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产品数：86101
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T28266Org-6906；化合物 T28266Org6906|||Org 6906|||Org-6906 free；Org6906|||Org 6906|||Org-6906 free
Tylophorine analog Org-6906 is a potential anticancer and immunosuppressive agent. Org-6906 suppresses the translation of cellular regulatory proteins, including cyclin D1, at the elongation step. Org-6906 allosterically regulates the ATPase and chaperone activities of HSC70 by promoting ATP hydrolysis in the presence of specific RNA binding motifs (AUUUA) of cyclin D1 mRNA.
价 格：￥电议型 号：T28266产 地：中国大陆
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T28256OPC-14523 free base；化合物 T28256OPC 14523|||VPI013|||VPI-013|||OPC14523|||OPC-14523|||VPI 013；OPC 1452
OPC-14523, a 5-HT1A receptor agonist, is used potentially for the treatment of depression and neuropathic pain.
价 格：￥电议型 号：T28256产 地：中国大陆
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T28221NVP-QAV-680；化合物 T28221NVPQAV680|||NVP-QAV 680|||NVP-QAV680|||NVP-QAV680|||NVP QAV 680|||QAV690 free
NVP-QAV-680 is a potent and selective antagonist of CRTh2 receptor. NVP-QAV-680 has nM functional potency for inhibition of CRTh2 driven human eosinophil and Th2 lymphocyte activation in vitro.
价 格：￥电议型 号：T28221产 地：中国大陆
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T28080Mocravimod；化合物 T28080KRP 203 free base|||KRP-203|||KRP203；KRP 203 free base|||KRP-203|||KRP203
Mocravimod is an agonist of sphingosine 1-phosphate receptor type 1. Mocravimod ameliorates atherosclerosis in LDL-R-/- mice. KRP-203 attenuates rat autoimmune myocarditis. KRP-203 combined with cyclosporine prolonged graft survival and abrogated transplant vasculopathy in rat heart allografts.
价 格：￥电议型 号：T28080产 地：中国大陆
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T28072LMLN-3897 TFA；MLN-3897三氟乙酸盐MLN-3897 TFA(1010731-97-1 Free base)；MLN-3897 TFA(1010731-97-1 Free base)
MLN-3897 TFA is a potent CCR1 antagonist that inhibits the binding of 125I-MIP-1α to THP-1 cell membranes.
价 格：￥电议型 号：T28072L产 地：中国大陆
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T28038Milademetan HCl (1398568-47-2 free base)；化合物 T28038Milademetan HCl|||DS3032|||DS 3032|||DS-3032|||DS
Milademetan is a potent and selective MDM2 inhibitor. MDM2 inhibitor DS-3032b binds to and prevents the binding of MDM2 protein to the transcriptional activation domain of the tumor suppressor protein p53 upon oral administration. By preventing this MDM2-p53 interaction, the proteosome-mediated enzymatic degradation of p53 is inhibited and the transcriptional activity of p53 is restored. This results in the restoration of p53 signaling and leads to the p53-mediated induction of tumor cell apopto
价 格：￥电议型 号：T28038产 地：中国大陆
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T27970Mabuterol free base；化合物 T27970Mabuterol|||PB 868Cl；Mabuterol|||PB 868Cl
Mabuterol is a selective agonist of β2 adrenoreceptor with no beta 1-stimulation. Mabuterol inhibited the positive inotropic effect of isoprenaline at 10(-7) g/ml and decreased the maximum driving frequency at 3 X 10(-6) g/ml. Mabuterol was 3 times more potent in relaxing the isolated rat uterus, but 700 times less potent than isoprenaline in relaxing the rabbit jejunum. Mabuterol (p.o.) depressed the intestinal propulsion and was equipotent to isoprenaline and 2.5 times less potent than salbuta
价 格：￥电议型 号：T27970产 地：中国大陆
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T27947LLY339434 HCl；化合物LY339434盐酸盐LY339434 HCl(219566-62-8 Free base)；LY339434 HCl(219566-62-8 Free base)
LY339434 HCl is a low affinity GluR5 erythrocyte receptor agonist.LY339434 HCl causes rapid neuronal death primarily by affecting N-methyl-D-aspartate (NMDA) receptors.
价 格：￥电议型 号：T27947L产 地：中国大陆
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T27930LY-127210 free base；化合物 T27930LY 127210|||LY127210；LY 127210|||LY127210
LY-127210 free base is peripheral arterial vasodilator with antihypertensive activity.
价 格：￥电议型 号：T27930产 地：中国大陆
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T27830LLifarizine FA；利法利嗪甲酸盐Lifarizine FA(119514-66-8 Free base)；Lifarizine FA(119514-66-8 Free base)
Lifarizine FA is a sodium channel blocker used in the treatment of neurological disorders and cardiovascular diseases, study of stroke.
价 格：￥电议型 号：T27830L产 地：中国大陆
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T2782LCatharanthine Tartrate(2468-21-5(free base))；化合物Catharanthine TartrateCatharanthine Tartrate(2468-21
Catharanthine Tartrate is a natural product isolated from Madagascar periwinkle, Catharanthine Tartrate inhibits voltage-operated L-type Ca2+ channel, with anti-cancer and blood pressure-lowering activity
价 格：￥电议型 号：T2782L产 地：中国大陆
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T27787LL-797,591 hydrochloride；L-797,591盐酸盐L-797,591 hydrochloride(217480-24-5 Free base)；L-797,591 hydroch
L-797,591 hydrochloride is active for somatostatin receptor isoform 1 (SSTR1). L-797,591 hydrochloride is commonly used in combination with AG1478 to enhance p-ERK5 expression in SSTR1 cells. L-797,591 hydrochloride significantly enhanced p38 phosphorylation in cotransfected cells, and this effect was reversed in combination with AG1478.
价 格：￥电议型 号：T27787L产 地：中国大陆
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T27773LL-739750 2HCl；L-739750盐酸盐L-739750 2HCl(160141-08-2 Free base)；L-739750 2HCl(160141-08-2 Free base)
L-739750 2HCl is a potent inhibitor of peptidomimetic farnesyltransferase, a novel pseudopeptide mimetic with potential anticancer activity.
价 格：￥电议型 号：T27773L产 地：中国大陆
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T27748LKRP-199 sodium；化合物KRP-199钠盐KRP-199 sodium(221164-28-9 Free base)；KRP-199 sodium(221164-28-9 Free bas
KRP-199 sodium sodium is highly potent and selective for AMPA-R in vitro and exhibits good neuroprotection in vivo.
价 格：￥电议型 号：T27748L产 地：中国大陆
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T27743KRH-594 free acid；化合物 T27743WK14922K|||WK-1492|||WK-14922K|||WK1492；WK14922K|||WK-1492|||WK-14922K||
KRH-594 is a potent, specific and insurmountable AT1 receptor antagonist. KRH-594 ameliorates hyperlipidaemia and nephropathy in diabetic spontaneously hypertensive rats. KRH-594 prevents end-organ damage in stroke-prone spontaneously hypertensive/Izm rats.
价 格：￥电议型 号：T27743产 地：中国大陆
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T27723LKDM5-C49 HCl；KDM5-C49醋酸盐KDM5-C49 HCl(1596348-16-1 Free base)|||KDOAM-20 hydrochloride；KDM5-C49 H
KDM5-C49 HCl (KDOAM-20 hydrochloride) is a potent and selective inhibitor of KDM5 demethylase. KDM5-C49 HCL(1596348-16-1 Free base) is a candidate compound for the treatment of cancer.
价 格：￥电议型 号：T27723L产 地：中国大陆
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T27682CCR2 antagonist 5；化合物CCR2 antagonist 5JNJ-41443532|||JNJ-41443532 Free Base|||JNJ 41443532|||JNJ4144
CCR2 antagonist 5 (JNJ-41443532) is a selective and orally active hCCR2 inhibitor with good binding affinity (IC50=37 nM) and potent functional antagonism (chemotaxis IC50=30 nM).JNJ-41443532 binds mCCR2 with a Ki of 9.6 ?M, which can be used to study inflammatory diseases and diabetes. diseases and diabetes.
价 格：￥电议型 号：T27682产 地：中国大陆
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T27474GSK-345931A；化合物 T27474GSK-345931A free acid|||GSK 345931A free acid|||GSK 345931A；GSK-345931A free a
GSK-345931A, an EP(1) receptor antagonist, shows measurable CNS penetration in the mouse and rat and potent analgesic efficacy in acute and sub-chronic models of inflammatory pain.
价 格：￥电议型 号：T27474产 地：中国大陆
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T27400LGanaplacide phosphate；化合物Ganaplacide phosphateGanaplacide phosphate (1261113-96-5 Free base)；Ganapla
Ganaplacide phosphate exerts multi-stage antimalarial activity against Plasmodium symptomatic asexual blood-stage infections, and is able to prevent transmission and block infection in animal models.
价 格：￥电议型 号：T27400L产 地：中国大陆
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T27386FR-295389；化合物 T27386FR-295389 Free Base|||FR295389；FR-295389 Free Base|||FR295389
FR-295389 is a cephalosporin. FR-295389 shows effective antibacterial activity against metallo-beta-lactamase (MBL)-producers in vitro.
价 格：￥电议型 号：T27386产 地：中国大陆
