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T1619Trazodone hydrochlorideKB-831;AF-1161;Trazodone HCl;盐酸曲唑酮
Trazodone hydrochloride is a serotonin uptake inhibitor that is used as an antidepressive agent. It has been shown to be effective in patients with major depressive disorders and other subsets of depressive disorders. It is generally more useful in depres
价 格:¥电议型 号:T1619产 地:中国大陆
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T16116MLN-4760
MLN-4760 is an angiotensin-converting (ACE2) inhibitor(human ACE2;IC50=0.44 nM). It also has excellent selectivity (>5000-fold) versus related enzymes including human testicular ACE (IC50, >100 μM) and bovine carboxypeptidase A (CPDA; IC50, 27 μM).
价 格:¥电议型 号:T16116产 地:中国大陆
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T15719Latanoprostene bunodLBN;NCX116
Latanoprostene bunod is nitric oxide (NO)-donating prostaglandin F2a analog and is a topical ophthalmic therapeutic. It is used for the reduction of intraocular pressure (IOP) in patients with open-angle glaucoma or ocular hypertension (OHT).
价 格:¥电议型 号:T15719产 地:中国大陆
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T15247ESI-05NSC 116966
ESI-05 is a specific EPAC2 (exchange protein directly activated by cAMP 2) antagonist (IC50: 0.4 μM). ESI-05 inhibits cAMP-mediated activation of EPAC2, as well as EAPC2, mediated Rap1 activation.
价 格:¥电议型 号:T15247产 地:中国大陆
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T14116ACP-105
ACP-105 is a novel and potent nonsteroidal selective androgen receptor modulator (SARM) with partial agonist activity relative to the natural androgen testosterone.
价 格:¥电议型 号:T14116产 地:中国大陆
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T11699J-113863
J-113863 is also a potent antagonist of the human CCR3 (IC50 of 0.58 nM) , but a weak antagonist of the mouse CCR3 (IC50 of 460 nM). J-113863 is inactive against CCR2, CCR4 and CCR5, as well as the LTB4 or TNF-α receptors. Anti-inflammatory effect. J-1138
价 格:¥电议型 号:T11699产 地:中国大陆
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T11696IvachtinCaspase-3 Inhibitor VII
Ivachtin is a nonpeptide, noncompetitive and reversibl caspase-3 inhibitor(IC50 = 23 nM) and is a modest inhibitor of the remaining caspases.
价 格:¥电议型 号:T11696产 地:中国大陆
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T1169Moguisteine莫吉司坦;BBR-2173
Moguisteine is a new-type peripheral non-narcotic antitussive drug.
价 格:¥电议型 号:T1169产 地:中国大陆
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T11689ITI-214ITI214
ITI214 is a picomolar PDE1 inhibitor with excellent selectivity against other PDE family members and against a panel of enzymes, receptors, transporters, and ion channels, exhibits potent PDE1 inhibitory activity (Ki = 58 pM).
价 格:¥电议型 号:T11689产 地:中国大陆
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T11685Isolongifolene异长叶烯;(-)-Isolongifolene
Isolongifolene has antioxidant, anti-inflammatory, anticancer and neuroprotective properties. Isolongifolene is a tricyclic sesquiterpene isolated from Murraya koenigii. Isolongifolene attenuates Rotenone-induced oxidative stress, mitochondrial dysfunctio
价 格:¥电议型 号:T11685产 地:中国大陆
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T11684Isoguvacine hydrochloride异四氢烟酸;1,2,3,6-tetrahydro-4-pyridinecarboxylic acid hydrochloride
Isoguvacine hydrochloride is a GABA receptor agonist. Isoguvacine hydrochloride binds to rat synaptic cortical membranes and activates α1β2γ2S, α2β2γ2S, α3β2γ2S, α5β2γ2S, and ρ1 subunit GABAA receptors.
价 格:¥电议型 号:T11684产 地:中国大陆
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T11680Isoasatone A
Isoasatone A acts against S. litura by acting on cytochrome P450 monooxygenase and glutathione transferase. Isoasatone A is a natural product isolated from Heterotropa takaoi M..
价 格:¥电议型 号:T11680产 地:中国大陆
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T1168Desonide地索奈德;Prednacinolone;Tridesilon;Locapred
Desonide is a synthetic glucocorticosteroid for topical use, with anti-inflammatory activity. Desonide binds to glucocorticoid receptors in the cytoplasm, and the ligand-receptor complex is translocated as a homodimer into the nucleus, where transcription
价 格:¥电议型 号:T1168产 地:中国大陆
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T11676Iriflophenone 3-C-glucosideIriflophenone 3-C-β-D-glucopyranoside
Iriflophenone 3-C-glucoside,has antioxidant activity,isolated from Cyclopia genistoides.
价 格:¥电议型 号:T11676产 地:中国大陆
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T11673IRAK4-IN-4
IRAK4-IN-4 inhibits cyclic GMP-AMP synthase (cGAS) with an IC50 of 2.1 nM.IRAK4-IN-4 is an interleukin-1 receptor–associated kinase 4 (IRAK4) inhibitor, has an IC50 of 2.8 nM.
价 格:¥电议型 号:T11673产 地:中国大陆
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T1167Cyproterone acetateAndrocur;Cyproterone 17-O-acetate;醋酸环丙氯地孕酮;醋酸环丙孕酮
Cyproterone binds the androgen receptor (AR), thereby preventing androgen-induced receptor activation in target tissues and inhibiting the growth of testosterone-sensitive tumor cells. Cyproterone Acetate is the acetate salt of a synthetic steroidal antia
价 格:¥电议型 号:T1167产 地:中国大陆
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T11669IR415
IR415 selectively interacts with Hepatitis B virus X protein (HBx, Kd = 2 nM) and blocks HBV-mediated RNAi suppression, reverses the inhibitory effect of HBx protein on the activity of the dicer endoribonuclease. IR415 is a potent anti-HBV agent and inhib
价 格:¥电议型 号:T11669产 地:中国大陆
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T11666IPR-803
IPR-803 binds directly to uPAR with sub-micromolar affinity. IPR-803 displays anti-tumor activity.IPR-803 is a potent inhibitor of the uPAR uPA protein-protein interaction (PPI).
价 格:¥电议型 号:T11666产 地:中国大陆
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T1166Ellipticine玫瑰树碱;Elliptisine;NSC 71795
Ellipticine is a potent antineoplastic agent exhibiting multiple mechanisms of action, IC50 of 0.67±0.06, 1.25±0.13, 1.25±0.13, 0.67±0.06, 0.27±0.02, 0.49±0.04, 0.44±0.03, and 1.48±0.62 μM for Leukemia HL-60, Breast adenocarcinoma MCF-7, Breast adenocarci
价 格:¥电议型 号:T1166产 地:中国大陆