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  • T0975ChloroambucilChloroambucil,WR-139013,CB-1348

    Chlorambucil is an orally-active antineoplastic aromatic nitrogen mustard. Chlorambucil alkylates and cross-links DNA during all phases of the cell cycle, resulting in disruption of DNA function, cell cycle arrest, and apoptosis.

    价 格：￥电议型 号：T0975产 地：美洲

  • T12269NUCC-390NUCC-390

    NUCC-390 is a selective agonist of small-molecule CXCR4 receptor.

    价 格：￥电议型 号：T12269产 地：美洲

  • T12390PDE1-IN-2PDE1-IN-2

    PDE1-IN-2 is an PDE1 inhibitor(PDE1C, PDE1B and PDE1A with IC50 values of 6, 140 and 164 nM, respectvely).

    价 格：￥电议型 号：T12390产 地：美洲

  • T13774ML390ML390

    ML390 exerts its potent differentiation effect on multiple leukemia models.

    价 格：￥电议型 号：T13774产 地：美洲

  • T1390PanthenolPanthenol,DL-Pantothenyl alcohol,DL-Panthenol

    Panthenol (pantothenol) is the alcohol analog of pantothenic acid (vitamin B5) and is thus a provitamin of B5. In organisms, it is quickly oxidized to pantothenate.

    价 格：￥电议型 号：T1390产 地：美洲

  • T16390OmtriptolideOmtriptolide

    Omtriptolide, triptolide purified from the Chinese herb, is a water-soluble derivative prodrug.

    价 格：￥电议型 号：T16390产 地：美洲

  • T1916ApitolisibApitolisib,GNE 390,RG 7422

    Apitolisib, an effective, class I PI3K inhibitor for PI3Kα（IC50=5 nM）, PI3Kβ（IC50=27 nM）, PI3Kδ（IC50=7 nM）, PI3Kγ （IC50=14 nM）, is used in trials study of solid cancers, breast cancer, prostate cancer, renal cell carcinoma, and endometrial carcinoma, amon

    价 格：￥电议型 号：T1916产 地：美洲

  • T2219Puromycin dihydrochloridePuromycin dihydrochloride,CL13900 dihydrochloride,Puromycin 2HCl

    Puromycin hydrochloride is a cinnamamido ADENOSINE found in STREPTOMYCES alboniger. It inhibits protein synthesis by binding to RNA. It is an antineoplastic and antitrypanosomal agent and is used in research as an inhibitor of protein synthesis.

    价 格：￥电议型 号：T2219产 地：美洲

  • T5013BrequinarBrequinar,NSC 368390,DUP785

    Brequinar is a potent inhibitor of dihydroorotate dehydrogenase, with potent activities against a broad spectrum of viruses.

    价 格：￥电议型 号：T5013产 地：美洲

  • T5175azd1390azd1390

    AZD1390 is an exceptionally potent inhibitor of ATM in cells (IC50: 0.78 nM) with >10,000-fold selectivity over closely related members of the PIKK family of enzymes.

    价 格：￥电议型 号：T5175产 地：美洲

  • T6390Anagrelide HClAnagrelide HCl,Anagrelide hydrochloride,BL4162A

    Anagrelide Hydrochloride(BL4162A) is a drug used for the treatment of essential thrombocytosis.

    价 格：￥电议型 号：T6390产 地：美洲

  • T8761L[Leu15]-Gastrin I human acetate(39024-57-2 Free base)；化合物 [Leu15]-Gastrin I human acetate(39024-57-2

    [Leu15]-Gastrin I human acetate(39024-57-2 Free base) is a useful organic compound for research related to life sciences and the catalog number is T8761L.

    价 格：￥电议型 号：T8761L产 地：中国大陆

  • T8457NPS2390；化合物NPS2390NPS2390

    NPS2390 is a first generation quinoxaline derivative that acts as a noncompetitive antagonist of mGluR1 and mGluR5 (IC50 of 5.2 and 82 nM, respectively)

    价 格：￥电议型 号：T8457产 地：中国大陆

  • T839096-hydroxy Buspirone；化合物 6-hydroxy BuspironeBMY 28674|||BMS-52821；BMY 28674|||BMS-52821

    6-Hydroxy Buspirone, an active metabolite of the anxiolytic compound buspirone, is produced via the cytochrome P450 (CYP) isoform CYP3A4. This compound exhibits affinity for the serotonin (5-HT) receptor subtype 5-HT1A, demonstrating efficacy in the rat hippocampus and dorsal raphe with half-maximal effective concentrations (EC50s) of 4 and 1 ?M, respectively. Furthermore, 6-Hydroxy Buspirone acts as a potent antagonist against dopamine D2, D3, and D4 receptors with half-maximal inhibitory conce

    价 格：￥电议型 号：T83909产 地：中国大陆

  • T83908DXR Inhibitor 11a (free acid)；化合物 DXR Inhibitor 11a (free acid)1-Deoxy-D-Xylulose-5-phosphate Reduct

    DXR inhibitor 11a, with an IC50 of 0.11 ?M, effectively inhibits P. falciparum 1-deoxy-D-xylulose-5-phosphate reductoisomerase (DXR). It also hampers the growth of P. falciparum in isolated human erythrocytes, demonstrating an IC50 of 0.37 ?M.

    价 格：￥电议型 号：T83908产 地：中国大陆

  • T8390710-Chloroestra-1,4-diene-3,17-dione；化合物 10-Chloroestra-1,4-diene-3,17-dione10-chloro-1,4-Estradiene；

    10-Chloroestra-1,4-diene-3,17-dione acts as an estrogen receptor α (ERα) agonist, enhancing reporter gene expression in S. cerevisiae with an EC50 of 0.36 nM for the human receptor. Additionally, it functions as an aromatase inhibitor, exhibiting an IC50 of 2.4 ?M.

    价 格：￥电议型 号：T83907产 地：中国大陆

  • T83906Tirzepatide sodium；化合物 Tirzepatide sodiumLY3298176；LY3298176

    Tirzepatide acts as an agonist for both the glucagon-like peptide 1 receptor (GLP-1R) and G protein-coupled receptor 119 (GPR119), effectively inducing cAMP production in HEK293 cells that express either human GLP-1R or GPR119, with EC50 values of 6.54 and 1.01 nM, respectively. Additionally, at a concentration of 100 nM, it triggers receptor internalization in these cells. In vivo studies demonstrate that tirzepatide, administered at 10 nmol/kg per day, significantly reduces body weight, food i

    价 格：￥电议型 号：T83906产 地：中国大陆

  • T83905Brain Natriuretic Peptide-32 (rat) acetate；化合物 Brain Natriuretic Peptide-32 (rat) acetateBNP (14-45)

    Brain natriuretic peptide-32 (BNP-32), a fragment of the proBNP cardiovascular hormone precursor, exhibits affinity for natriuretic peptide receptors in rat vascular smooth muscle cells (IC50 = 7.3 nM) and promotes cGMP accumulation within these cells (EC50 = 170 nM). Additionally, BNP-32 effectively mediates the relaxation of norepinephrine-precontracted isolated rat aortic strips (EC50 = 6.7 nM). Upon administration at a dosage of 3 ?g/kg, it elevates urine and urinary electrolyte outputs and

    价 格：￥电议型 号：T83905产 地：中国大陆

  • T83904Polymyxin E2 sulfate；化合物 Polymyxin E2 sulfateColistin B sulfate；Colistin B sulfate

    Polymyxin E2, a key component of the cationic lipopeptide antibiotic colistin, was originally derived from B. polymyxa and serves as a peptide antibiotic. It exhibits effective antibacterial activity against the plant pathogen X. oryzae, with an EC50 value of 0.21 ?g/ml, and has been shown to both prevent and mitigate rice bacterial leaf blight in greenhouse experiments at a dosage of 200 ?g/ml.

    价 格：￥电议型 号：T83904产 地：中国大陆

  • T83903Polymyxin B2 sulfate；化合物 Polymyxin B2 sulfatePolymyxin B2 sulfate

    Polymyxin B2, a significant component of polymyxin B, is an antibiotic cationic lipopeptide initially derived from B. polymyxa. This compound effectively inhibits P. aeruginosa, A. baumannii, K. pneumoniae, and E. cloacae strains, exhibiting minimum inhibitory concentrations (MICs) of 1-2, 0.5-1, 0.25-0.5, and 0.25-1 ?g/ml, respectively. Notably, in a mouse model of P. aeruginosa bloodstream infection, administration of polymyxin B2 at a dosage of 4 mg/kg has been shown to decrease the number of

    价 格：￥电议型 号：T83903产 地：中国大陆

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