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  • T38344Lalistat 1

    Lalistat 1 is an inhibitor of lysosomal acid lipase (LAL, IC50 = 68 nM) and IgA1 protease for H. influenzae. Lalistat 1 can be used in studies about niemann-pick type C diseases.

    价 格:¥电议型 号:T38344产 地:中国大陆

  • TP1245LACTH 4-11 acetateACTH 4 11 acetate,ACTH 411 acetate

    ACTH 4-11 acetate is an adrenocorticotropin hormone fragment and possesses the same amino acid sequence as α-melanocyte stimulating hormone (MSH) does. ACTH 4-11 acetate exhibits a weak MSH potency only at high doses (100 and 1000 nM).

    价 格:¥电议型 号:TP1245L产 地:中国大陆

  • T12788R(+)-IAA-94

    R(+)-IAA-94 is a potent indanyloxyacetic acid blocker of epithelial chloride channels. R(+)-IAA-94 inhibits Nef-sdAb19 (single-domain antibody) interaction and binds to negative factor (Nef).

    价 格:¥电议型 号:T12788产 地:中国大陆

  • T9820GPI-1485neurofunctional,regeneration,Inhibitor,ligand,stroke,GPI-1485,GPI 1485,inhibit,immunophilin,

    GPI-1485 (GM1485) is a nonimmunosuppressive immunophilin ligand, promoting neurofunctional improvement and neural regeneration following stroke.

    价 格:¥电议型 号:T9820产 地:中国大陆

  • T21495Spinosyn Ainhibit,Inhibitor,Spinosyn A

    Spinosyn A is a polyketide-derived macrolide produced by Saccharopolyspora spinosa and is an active ingredient in several commercial insecticides.

    价 格:¥电议型 号:T21495产 地:中国大陆

  • T7017WNK463Ser/Thr Protease,WNK 463,inhibit,WNK463,Serine proteases,Inhibitor,Serine endopeptidases,Threo

    WNK463 is a pan-WNK-kinase inhibitor. It effectively inhibits the in vitro kinase activity of all four WNK family members (WNK1/2/3/4).

    价 格:¥电议型 号:T7017产 地:中国大陆

  • T9428HM43239HM43239,HM-43239

    HM43239 is an orally active and selective FLT3 inhibitor with IC 50 s of 1.1 nM, 1.8 nM and 1.0 nM for FLT3 WT, FLT3 internal tandem duplication (ITD) and FLT3 D835Y kinases, respectively. HM43239 directly inhibits the kinase activity of FLT3 as a reversible Type I inhibitor and effectively modulates downstream p-STAT5 and p-ERK. HM43239 also demonstrated inhibition of SYK, JAK1/2 and TAK1. HM43239 inhibits the proliferation and induces the apoptosis of leukemic cells [1] [2] [3].

    价 格:¥电议型 号:T9428产 地:中国大陆

  • T80435α-Cholestane5α Cholestane,5αCholestane

    5α-Cholestane belongs to the class of organic compounds known as cholestane steroids.

    价 格:¥电议型 号:T8043产 地:中国大陆

  • T9884EN523inhibit,EN-523,Inhibitor,non-catalytic,EN523,OTUB1 recruiter,EN 523,deubiquitinase,allosteric c

    EN523 targets non-catalytic allosteric cysteine C23 in K48 ubiquitin-specific deuquitinase OTUB1.

    价 格:¥电议型 号:T9884产 地:中国大陆

  • T2344LLY 344864 racemateLY 344864 racemate

    LY 344864 racemate is a 5-HT1F receptor agonist.

    价 格:¥电议型 号:T2344L产 地:中国大陆

  • T6476Dofetilidecardiovascular,potent,specific,class,antiarrhythmic,orally,Inhibitor,UK68789,UK-68789,Dofe

    Dofetilide is a sulfonamide class III antiarrhythmic agent and potassium channel blocker. Dofetilide selectively blocks cardiac ion channels of the rapid component of the delayed rectifier potassium current Ikr. This antiarrhythmic agent prolongs cardiac action potential duration and effective refractory period due to delayed repolarization without affecting conduction velocity. This results in a normal sinus rhythm. Dofetilide is used in the treatment of atrial fibrillation and flutter.

    价 格:¥电议型 号:T6476产 地:中国大陆

  • T25824ML400

    ML400 is an allosteric inhibitor of LMPTP with an EC50 of 1μM. ML400 displays good cell-based activity and rodent pharmacokinetics.

    价 格:¥电议型 号:T25824产 地:中国大陆

  • Fr13734Compound Fr13734Compound Fr13734

    价 格:¥电议型 号:Fr13734产 地:中国大陆

  • T74747-NitroindazoleInhibitor,inhibit,7Nitroindazole,7 Nitroindazole,Nitric oxide synthases,7-Nitroindazo

    7-Nitroindazole is a non-selective inhibitor of NOS isoforms in vitro for neuronal nitric oxide synthase showing a 10-fold selectivity for neuronal NOS.

    价 格:¥电议型 号:T7474产 地:中国大陆

  • TN24364-methyl-6-phenyl-2H-pyranone

    4-methyl-6-phenyl-2H-pyranone is derived from Scutellaria baicalensis Georgi and improves mitochondrial functionality to protect astrocytes against hydrogen peroxide-induced toxicity.

    价 格:¥电议型 号:TN2436产 地:中国大陆

  • TNU0864HUP30

    HUP30 is a potent vasodilating agent. HUP30 can stimulate soluble guanylyl cyclase, activate K+ channels, and block extracellular Ca2+ influx.

    价 格:¥电议型 号:TNU0864产 地:中国大陆

  • TN1417Azadirachtinpest,inhibit,cytoskeleton,cellular,transduction,signal,insecticides,Apoptosis,Azadiracht

    Azadirachtin has antifungal activity, used as an insecticide.

    价 格:¥电议型 号:TN1417产 地:中国大陆

  • T8604FenaclonFenaclon

    Fenaclon is an anticonvulsant. It is indicated for the treatment of epilepsy.

    价 格:¥电议型 号:T8604产 地:中国大陆

  • T24711Ricinine

    Ricinine is a major alkaloid in Ricinus communis plant with hepatoprotection in CCl4 -induced liver damage.

    价 格:¥电议型 号:T24711产 地:中国大陆

  • T101474-Hydroxymephenytoin

    4-Hydroxymephenytoin is the metabolism of an antiepileptic drug mephenytoin. Mephenytoin is used as a CYP2C19 substrate.

    价 格:¥电议型 号:T10147产 地:中国大陆

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