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T834251-Oxomiltirone；化合物 1-Oxomiltirone1-Oxomiltirone
2-Isopropyl-8,8-dimethyl-7,8-dihydrophenanthrene-3,4,5(6H)-trione, a C20-norabietane diterpenoid exhibiting anti-inflammatory properties, is isolated from sage leaves [1].
价 格：￥电议型 号：T83425产 地：中国大陆
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T82940ATTO 425；化合物 ATTO 425ATTO 425
ATTO 425 is an uncharged fluorescent dye [1].
价 格：￥电议型 号：T82940产 地：中国大陆
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T82939ATTO 425 NHS ester；化合物 ATTO 425 NHS esterATTO 425 NHS ester
ATTO 425 NHS ester, a Rhodamine-structure-based fluorescent marker, exhibits strong absorption, high fluorescence quantum yield, and robust thermal and photochemical stability. This compound is ideal for applications in single molecule detection and high-resolution microscopy. As an NHS ester derivative of ATTO 425, it serves as a versatile labeling agent for proteins and antibodies.
价 格：￥电议型 号：T82939产 地：中国大陆
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T82923Bamadutide；化合物 BamadutideSAR425899；SAR425899
Bamadutide (SAR425899) is a potent dual agonist for the glucagon-like peptide-1 receptor and glucagon receptor, which notably enhances β-cell function and decreases the rate of glucose absorption in vivo, thereby improving postprandial glucose control. This compound has potential applications in type 2 diabetes research [1].
价 格：￥电议型 号：T82923产 地：中国大陆
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T82425Excitin 1；化合物 Excitin 1Excitin 1
Excitin 1, an orally active, CNS-penetrating peptide, modifies rat behavior and alters brain monoamine and amino acid levels [1].
价 格：￥电议型 号：T82425产 地：中国大陆
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T81973KR-27425；化合物 KR-27425KR-27425
Compound 13, an AChE activator 1, is a non-pyridinium oxime that reactivates paraoxon-inhibited acetylcholinesterase (AChE) [1].
价 格：￥电议型 号：T81973产 地：中国大陆
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T81425Polyporusterone C；化合物 Polyporusterone CPolyporusterone C
Polyporusterone C (Compound 3), a natural product extracted from Polyporus umbellatus, exhibits cytotoxic activities, displaying IC50 values of 37, 26, and 42 μg/mL against L-1210 cells after 3, 5, and 7 days of treatment, respectively [1].
价 格：￥电议型 号：T81425产 地：中国大陆
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T80425Jingzhaotoxin-V；化合物 Jingzhaotoxin-VJingzhaotoxin-V
Jingzhaotoxin-V, a 29-residue polypeptide from Chilobrachys jingzhao spider venom, selectively inhibits tetrodotoxin-resistant and tetrodotoxin-sensitive sodium currents in rat dorsal root ganglion neurons, with IC50 values of 27.6 nM and 30.2 nM, respectively. Furthermore, it suppresses Kv4.2 potassium currents in Xenopus laevis oocytes, with an IC50 of 604.2 nM [1].
价 格：￥电议型 号：T80425产 地：中国大陆
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T79425TGR5 agonist 4；化合物 TGR5 agonist 4TGR5 agonist 4
TGR5 agonist 4 (compound 19), a derivative of cholic acid, selectively activates the TGR5 receptor with an effective concentration (EC50) of 4 μM [1].
价 格：￥电议型 号：T79425产 地：中国大陆
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T78425GK16S；化合物 GK16SGK16S
GK16S, a UCHL1 chemogenomic probe, serves as a complementary tool to GK13S for the investigation of UCHL1 function in cellular studies [1].
价 格：￥电议型 号：T78425产 地：中国大陆
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T78334Surzebiclimab；化合物 SurzebiclimabBGB-A425；BGB-A425
Surzebiclimab (BGB-A425), a humanized variant IgG1 monoclonal antibody, targets and binds with high affinity (K D = 0.36 nM) and specificity to the extracellular domain of T-cell immunoglobulin and mucin-domain containing-3 (TIM-3). This compound is utilized in cancer research [1].
价 格：￥电议型 号：T78334产 地：中国大陆
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T76425(Glu20)-Amyloid β-Protein (1-42)；化合物 (Glu20)-Amyloid β-Protein (1-42)(Glu20)-Amyloid β-Protein (1-42
(Glu20)-Amyloid β-Protein (1-42) represents a variant of amyloid β-protein (Aβ) that fibrillizes more slowly. This is attributed to the Glu20 mutation, which diminishes Aβ42´s tendency to aggregate and inhibits the accumulation of this slowly fibrillizing peptide. Notably, amyloid β-protein serves as the principal constituent of amyloid deposits found in both the vascular system and brain parenchyma in Alzheimer´s disease [1] [2].
价 格：￥电议型 号：T76425产 地：中国大陆
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T75425Synephrine hemitartrate；化合物 Synephrine hemitartrateSynephrine hemitartrate
Synephrine hemitartrate (Oxedrine), an alkaloid extracted from Citrus aurantium, functions as both an α-adrenergic and β-adrenergic agonist. As a sympathomimetic compound, it has applications in weight loss [1] [2].
价 格：￥电议型 号：T75425产 地：中国大陆
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T74425Nepuvibart；化合物 NepuvibartNepuvibart
Nepuvibart (ZRC3308-B10), an IgG1 type anti-SARS-CoV-2 monoclonal antibody, exhibits strong binding affinity to a distinct non-competing epitope on the receptor-binding domain (RBD) of the SARS-CoV-2 spike protein. When combined in a 1:1 ratio with ZRC3308-A7, Nepuvibart is effective in preventing COVID-19 and in treating the early stages of the disease before it progresses to severe illness [1].
价 格：￥电议型 号：T74425产 地：中国大陆
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T74259PF15；化合物 PF15PF15
PF15, a selective FLT3-ITD degrader, serves as a PROTAC (proteolysis targeting chimera) tethering ligands for FLT3 kinase and CRBN. It exhibits a degradation concentration 50 (DC50) of 76.7 nM and notably impedes the proliferation of FLT3-ITD-positive cells. PF15 also reduces phosphorylation levels of FLT3 and STAT5 and demonstrates efficacy in inhibiting tumor growth in mouse models, suggesting potential applications in leukemia research [1].
价 格：￥电议型 号：T74259产 地：中国大陆
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T74258HL-8；化合物 HL-8HL-8
HL-8, a PROTAC molecule, effectively targets and degrades PI3K kinase completely at a concentration of 10 μM within 8 hours, showcasing potential for cancer research [1].
价 格：￥电议型 号：T74258产 地：中国大陆
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T74256PROTAC BRD9-binding moiety 5；化合物 PROTAC BRD9-binding moiety 5PROTAC BRD9-binding moiety 5
PROTAC BRD9-binding moiety 5, a selective binder of BRD9 with an IC50 value of 4.20 μM, is utilized in PROTAC synthesis and exhibits antiproliferative activity against cancer cells [1].
价 格：￥电议型 号：T74256产 地：中国大陆
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T74255HPA-IN-1；化合物 HPA-IN-1HPA-IN-1
HPA-IN-1 (Compound 1) serves as a potent and selective inhibitor of human pancreatic α-amylase (HPA), demonstrating specificity with IC50 values of 12.0 μM for HPA and 410.4 μM for α-glucosidase [1].
价 格：￥电议型 号：T74255产 地：中国大陆
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T74250Custirsen；化合物 CustirsenCustirsen
Custirsen, a highly specific antisense oligonucleotide, inhibits the production of clusterin—an antiapoptotic protein upregulated in response to chemotherapy, thereby conferring treatment resistance.
价 格：￥电议型 号：T74250产 地：中国大陆
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