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T5532BMS-687453BMS-687453
BMS-687453 is a potent and selective PPAR alpha agonist, with an EC(50) of 10 nM for human PPARalpha and approximately 410-fold selectivity vs human PPARgamma in PPAR-GAL4 transactivation assays.
价 格：￥电议型 号：T5532产 地：美洲
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T8345313-Oxo-ODE；化合物 13-Oxo-ODE13-Oxo-ODE
13-Oxo-ODE is an octadecadienoic acid isolated from moxa and Artemisia argyi leaves [1].
价 格：￥电议型 号：T83453产 地：中国大陆
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T8329AR 231453；化合物AR 231453AR 231453
AR 231453 is a selective and orally available GPR119 agonist,can stimulate β-cell replication and improve islet graft function.
价 格：￥电议型 号：T8329产 地：中国大陆
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T82453Epothilone D1；化合物 Epothilone D1Epothilone D1
Epothilone D1, a naturally derived isolate, exhibits cytotoxic effects on mouse fibroblasts.
价 格：￥电议型 号：T82453产 地：中国大陆
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T81453PITCOIN4；化合物 PITCOIN4PITCOIN4
PITCOIN4 is a Class II Alpha PI3K-C2α inhibitor with high selectivity, demonstrating nanomolar inhibition of PI3K-C2α and exhibiting over 100-fold selectivity against a broad kinase panel [1].
价 格：￥电议型 号：T81453产 地：中国大陆
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T80801WAY-612453；化合物 WAY-612453WAY-612453
WAY-612453 is an active compound utilized in researching amyloid diseases and synucleinopathies.
价 格：￥电议型 号：T80801产 地：中国大陆
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T80453GLP-1 (1-36) amide (human, rat)；化合物 GLP-1 (1-36) amide (human, rat)Glucagon-like Peptide 1 (1-36) am
GLP-1 (1-36) amide (human, rat) is a molecular variant of the GLP-1 (7-36) amide and has the capacity to stimulate [14C]aminopyrine accumulation in enzymatically dispersed, enriched rat parietal cells [1].
价 格：￥电议型 号：T80453产 地：中国大陆
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T79453Anticancer agent 134；化合物 Anticancer agent 134Anticancer agent 134
Anticancer Agent 134 (Compound 6a), an environment-sensitive fluorescent probe, induces apoptosis and selectively differentiates between tumor and normal tissues. This agent specifically targets nuclear bodies within tumor sections [1].
价 格：￥电议型 号：T79453产 地：中国大陆
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T78453Fast Blue B Salt；固兰BFast Blue B Salt
Fast Blue B Salt, a fat-soluble and phenolic compound-binding dye, serves for semi-quantitative analysis of alkylresorcinols in rye and forms a colored precipitate upon acetone exposure [1]. It also demonstrates affinity for diazonium compounds.
价 格：￥电议型 号：T78453产 地：中国大陆
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T7700Lersivirine；化合物Lersivirine(UK 453061)Lersivirine(UK 453061)|||UK-453061；3-氰基-5-[[3,5-二乙基-1-(2-羟基乙基)-
Lersivirine (UK-453061)(UK 453061) is a second-generation non-nucleoside reverse transcriptase inhibitor (NNRTI) under development for HIV infection therapy.
价 格：￥电议型 号：T7700产 地：中国大陆
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T76699Sabatolimab；Sabatolimab单抗MBG453|||NVP-MBG453；MBG453|||NVP-MBG453
Sabatolimab (MBG453), a humanized IgG4 (S228P) antibody targeting TIM-3, is a potent inhibitory receptor that regulates adaptive and innate immune responses. Sabatolimab has potential immunosuppressive activity and selectively binds to TIM-3 on immune cells and bone marrow cells.
价 格：￥电议型 号：T76699产 地：中国大陆
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T76453Substance P (6-11)；化合物 Substance P (6-11)Substance P (6-11)
Substance P (6-11), the C-terminal hexapeptideamide of Substance P, exhibits affinity for the NK-1 tachykinin receptor, leading to motoneuron depolarization and a hypotensive effect [1] [2].
价 格：￥电议型 号：T76453产 地：中国大陆
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T7545311-epi-Chaetomugilin I；化合物 11-epi-Chaetomugilin I11-epi-Chaetomugilin I
11-epi-Chaetomugilin I, a metabolite identified in Chaetomium globosum, demonstrates notable cytotoxic activity against several cell lines, including the murine P388 and L1210 leukemia cell lines, the human HL-60 leukemia cell line, and the human KB epidermoid carcinoma cell line [1].
价 格：￥电议型 号：T75453产 地：中国大陆
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T74539DIZ-3；化合物 DIZ-3DIZ-3
DIZ-3, a selective multimeric G-quadruplex (G4) ligand, employs a G4-ligand-dimerizing approach to intercalate into the G4-G4 interface, thereby stabilizing its higher-order structure. This compound effectively induces cell cycle arrest and apoptosis, inhibiting cell proliferation in cancer cells characterized by alternative lengthening of telomeres (ALT) [1].
价 格：￥电议型 号：T74539产 地：中国大陆
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T74538Galectin-3 antagonist 2；化合物 Galectin-3 antagonist 2Galectin-3 antagonist 2
Galectin-3, a β-galactoside-specific carbohydrate recognition protein (lectin), facilitates the migration of B-cell precursor acute lymphoblastic leukemia (BCP-ALL) cells and demonstrates resistance to pharmaceutical interventions.
价 格：￥电议型 号：T74538产 地：中国大陆
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T74537Antifungal agent 26；化合物 Antifungal agent 26Antifungal agent 26
Pradimicin A derivative 26 exhibits antifungal, antiviral, and antiparasitic properties by attaching to d-mannose (Man)-rich glycans in pathogenic organisms [1].
价 格：￥电议型 号：T74537产 地：中国大陆
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T74536IDO/Tubulin-IN-2；化合物 IDO/Tubulin-IN-2IDO/Tubulin-IN-2
IDO/Tubulin-IN-2 (HT2) is a powerful inhibitor of both TDO and tubulin. This compound demonstrates significant efficacy against various cancer cell lines, including U87, HepG2, A549, HCT-116, and LO2, with respective IC50 values of 0.43, 0.036, 0.041, 0.095, and 1.04 μM. Additionally, IDO/Tubulin-IN-2 markedly enhances antitumor activity [1].
价 格：￥电议型 号：T74536产 地：中国大陆
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T74530GEM-5；化合物 GEM-5GEM-5
GEM-5, a gemcitabine-based conjugate incorporating a HIF-1α inhibitor (YC-1) (IC 50 =30 nM), notably suppresses HIF-1α expression while enhancing tumor suppressor p53 expression. It induces apoptosis in A2780 cells and curbs tumor growth [1].
价 格：￥电议型 号：T74530产 地：中国大陆
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T7453(E)-m-Coumaric acid；3-羟基肉桂酸m-Coumarate|||3-Hydroxycinnamic acid|||m-Coumaric acid|||meta-Coumaric ac
(E)-m-Coumaric acid (3-Hydroxycinnamic acid) is a natual product isolated from Cinnamomum cassia Presl . 3-Hydroxycinnamic acid has antioxidant activity.
价 格：￥电议型 号：T7453产 地：中国大陆
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T74453JPS014；化合物 JPS014JPS014
JPS014, a benzamide-based Von Hippel-Lindau (VHL) E3-ligase proteolysis targeting chimera (PROTAC), effectively degrades class I histone deacetylase (HDAC), exhibiting potency as an HDAC1/2 degrader. This correlation is associated with an increase in differentially expressed genes and enhanced apoptosis in HCT116 cells [1].
价 格：￥电议型 号：T74453产 地：中国大陆
