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产品数:86101
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T9849HQ461cyclin K degrader,Cyclin dependent kinase,molecular glue,HQ461,HQ 461,HQ-461,CDK12 substrate ph
HQ461 is a molecular glue that promotes CDK12-DDB1 interaction to trigger cyclin K degradation, resulting in decreased CDK12 substrate phosphorylation, downregulation of DNA damage response genes, and cell death.
价 格:¥电议型 号:T9849产 地:中国大陆
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T8464RA-9Unfolded,RA-9,cancer,RA 9,DUBs,Inhibitor,Apoptosis,Response,Deubiquitinase,cells,inhibit,Protein
RA-9 is a potent and selective proteasome-associated inhibitor of deubiquitinating enzymes (DUBs), with favorable toxicity profile and anticancer activity. RA-9 selectively induces apoptosis in ovarian cancer cell lines.
价 格:¥电议型 号:T8464产 地:中国大陆
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T3079GSK1838705ACD246,Anaplastic lymphoma kinase,inhibit,Cluster of differentiation 246,Anaplastic lympho
GSK1838705A is an effective IGF-1R inhibitor (IC50: 2.0 nM), modestly potent to IR (IC50: 1.6 nM) and ALK (IC50: 0.5 nM), respectively, and little inhibition to other protein kinases.
价 格:¥电议型 号:T3079产 地:中国大陆
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TN1468(-)-Carvone( ) Carvone,()Carvone
(-)-Carvone is a natural product which probably has antioxidant and anti-inflammatory capabilities.
价 格:¥电议型 号:TN1468产 地:中国大陆
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T6461Dapoxetine hydrochlorideBenign,BPH,serotonin reuptake,SERT,sexual disorder,LY210448,SLC6A4,Dapoxetin
Dapoxetine HCl is a selectivity short-acting serotonin reuptake inhibitor, used for the therapy of premature ejaculation.
价 格:¥电议型 号:T6461产 地:中国大陆
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T7134MavacamtenMyosin,Inhibitor,inhibit,SAR 439152,SAR-439152,Mavacamten,MYK 461,MYK461
MYK-461 is an orally bioavailable inhibitor of cardiac myosin ATPase,( IC50s of 490, 711 nM for bovine cardiac and human cardiac, respectively)
价 格:¥电议型 号:T7134产 地:中国大陆
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T6462DeltarasinDeltarasin,Phosphodiesterase (PDE),inhibit,Inhibitor,Ras
Deltarasin is a small molecular inhibitor of KRAS-PDEδ interaction with Kd of 38 nM for binding to purified PDEδ.
价 格:¥电议型 号:T6462产 地:中国大陆
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TJS0405LucidinInhibitor,Lucidin,NSC-30546,NSC30546,inhibit
1. Lucidin and its derivatives are genotoxic, it is mutagenic at the hypoxanthine-guanine phosphoribosyl transferase gene locus.
价 格:¥电议型 号:TJS0405产 地:中国大陆
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T6S2246Alisol B 23-acetateInhibitor,inhibit,Alisol B 23 acetate,Alisol B 23acetate,Alisol B 23-acetate
1. Alisol B 23-acetate produces protective effect against ANIT-induced hepatotoxity and cholestasis, due to FXR-mediated regulation of transporters and enzymes. 2. Alisol B 23-acetate produces promotive effect on liver regeneration, due to FXR-mediated regulation of genes involved in hepatocyte proliferation and hepato-protection. 3. Alisol B 23-acetate produces a protective effect against CCl4-induced hepatotoxicity, due to FXR and STAT3-mediated gene regulation.
价 格:¥电议型 号:T6S2246产 地:中国大陆
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T8046Tosufloxacin tosylate hydrateTosufloxacin tosylate hydrate,Bacterial,Inhibitor,Tosufloxacin tosylate
Tosufloxacin p-Toluenesulfonate Hydrate is a fluoroquinolone antibacterial agent that is used to treat susceptible infections.
价 格:¥电议型 号:T8046产 地:中国大陆
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TQ0046BavisantJNJ31001074,JNJ 31001074,Neurological disorders,inhibit,Histamine Receptor,attention-deficit
Bavisant is a selective and orally active Human H3 receptor antagonist. Bavisant can be used in research on mechanisms of action, involving wakefulness and cognition and the treatment for ADHD.
价 格:¥电议型 号:TQ0046产 地:中国大陆
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TQ0296LN-Nornuciferine hydrochloride(4846-19-9 free base)NNornuciferine hydrochloride(4846199 free base),N
N-Nornuciferine is an aporphine alkaloid in lotus leaf, significantly inhibits CYP2D6 (IC50: 3.76 μM, Ki: 2.34 μM).
价 格:¥电议型 号:TQ0296L产 地:中国大陆
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TP1696LCGGRGD acetate(1260223-44-6 free base)CGGRGD acetate(1260223446 free base),CGGRGD acetate(1260223 44
CGGRGD acetate is a RGD derivative with cysteine as the n-terminal. CGGRGD was synthesized by solid phase peptide synthesis technology, and amino2-cyanobenzothiazole (2-cyanobenzothiazole) (2-cyanobenzothiazole (CBT) was added on the surface of PCL fiber for ammoniation.
价 格:¥电议型 号:TP1696L产 地:中国大陆
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T8846beta-Escinproliferation,anti-angiogenic,β-Escin,fibroblast growth factor,betaEscin,CAM angiogenesis,
beta-Escin is a natural mixture of triterpenoid saponins isolated from horse chestnut (Aesculus hippocastanum) seeds, can be used as a vasoprotective anti-inflammatory, anti-edematous and anti-nociceptive agent.
价 格:¥电议型 号:T8846产 地:中国大陆
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T7046Xylazinesedative,BAY1470,Adrenergic Receptor,BAY-1470,Xylazine,veterinary,Inhibitor,Beta Receptor,an
Xylazine is α2-adrenergic receptor agonist.
价 格:¥电议型 号:T7046产 地:中国大陆
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T6748A-1155463Bcl-2 Family,Inhibitor,A-1155463,inhibit
A-1155463, a highly potent and selective BCL-XL inhibitor, shows picomolar binding affinity to BCL-XL, and >1000-fold weaker binding to BCL-2 and related proteins BCL-W(Ki=19 nM) and MCL-1(Ki>440 nM).
价 格:¥电议型 号:T6748产 地:中国大陆
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T7321MBP146-78Parasite,MBP-146-78,MBP146-78,MBP146 78,inhibit,MBP14678,Inhibitor
MBP146-78 is a potent and selective cGMP inhibitor dependent protein kinases.
价 格:¥电议型 号:T7321产 地:中国大陆
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T8685SP-146SP146,SP 146
SP-146 is a selective, potent and non-ATP-competitive Aurora B inhibitor(IC50 : 0.316 nM).
价 格:¥电议型 号:T8685产 地:中国大陆
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T6986SivelestatEI 546,Inhibitor,Sivelestat,ischemia,inhibit,LY 544349,Acute,EI-546,reperfusion,LY-544349,
Sivelestat is a potent and selective inhibitor of neutrophil elastase with IC50 of 44 nM.
价 格:¥电议型 号:T6986产 地:中国大陆
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TN6464HemiphloinHemiphloin,Inhibitor,inhibit
Hemiphloin is a natural flavonoid isolated from the roots of Dalbergia odorifera.
价 格:¥电议型 号:TN6464产 地:中国大陆