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T4714Methyl indole-3-acetateMethyl indole-3-acetate,Indole-3-acetic acid, methyl ester,
Indole-3-methyl acetate is found in apple. It is isolated from immature seeds of beach pea (Lathyrus maritimus), Vicia amurensis, wild soybean (Glycine soja), lobiya (Vigna catiang var. sinensis) and hyacinth bean (Dolichos lablab).
价 格:¥电议型 号:T4714产 地:美洲
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T4716Pyrrole-2-carboxylic acidPyrrole-2-carboxylic acid,2-Pyrrolecarboxylic acid,Minaline
Pyrrole-2-carboxylic acid was first identified as a degradation product of sialic acids, then as a derivative of the oxidation of the D-hydroxyproline isomers by mammalian D-amino acid oxidase. The latter relationship results from the lability of the dire
价 格:¥电议型 号:T4716产 地:美洲
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T471725-Hydroxycholesterol25-Hydroxycholesterol
25-Hydroxycholesterol is a steroid derivative that suppresses the cleavage of sterol regulatory element binding proteins (SREBPs). It inhibits HMG-CoA reductase and so it also plays a significant role in the in vivo regulation of cholesterol biosynthesis
价 格:¥电议型 号:T4717产 地:美洲
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T4719D-Gulonic acid γ-lactoneD-Gulonic acid γ-lactone
L-Gulonolactone (also known as reduced ascorbic acid, RAA) is the substrate of the enzyme L-gulono-1,4-lactone oxidoreductase (EC 1.1.3.8), which catalyzes the last step of the biosynthesis of L-ascorbic acid (vitamin C) in plants and animals. The enzyme
价 格:¥电议型 号:T4719产 地:美洲
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T5471GUANABENZGUANABENZ
GUANABENZ is a Central alpha-2 Adrenergic Agonist. The mechanism of action of guanabenz is as an Adrenergic alpha2-Agonist.
价 格:¥电议型 号:T5471产 地:美洲
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T5531GSK-4716GSK-4716
GSK4716 is an ERRβ/γ agonist (IC50 = 2 μM) that can activate the receptor with similar potency as the protein ligand
价 格:¥电议型 号:T5531产 地:美洲
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T8738LUN42518 HCl 47142-51-8(free base);化合物LUN42518 HClLUN42518 HCl 47142-51-8(free base)
LUN42518 HCl is an analogue of phentolamine. Phentolamine is a nonselective alpha-adrenergic antagonist.
价 格:¥电议型 号:T8738产 地:中国大陆
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T8690Brexpiprazole HCl;化合物Brexpiprazole HClOPC 34712 dihydrochloride;OPC 34712 dihydrochloride
Brexpiprazole HCl (OPC 34712 dihydrochloride) is a new antipsychotic drug.
价 格:¥电议型 号:T8690产 地:中国大陆
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T8553BC-1471;化合物 T8553BC-1471
BC-1471 is a STAM-binding protein (STAMBP) deubiquitinase inhibitor. BC-1471 inhibits inflammasome activity of NALP7 (NACHT, LRR and PYD domains-containing protein 7) [1].
价 格:¥电议型 号:T8553产 地:中国大陆
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T8509Danicopan;化合物DanicopanACH-4471;ACH-4471
Danicopan (ACH-4471) (ACH-4471) is a selective, orally active small molecule factor D inhibitor with high binding affinity to human factor D, with a Kd value of 0.54 nM. Danicopan (ACH-4471) inhibits the activity of the complement replacement pathway (APC) and may block the complement replacement pathway in paroxysmal nocturnal hemoglobinuria (PNH) and atypical hemolytic uremic syndrome (aHUS).
价 格:¥电议型 号:T8509产 地:中国大陆
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T8486GW6471;化合物GW 6471GW 6471;GW 6471
GW6471 is a selective PPARα antagonist (IC50=0.24 μM) that enhances the binding affinity of the PPARα ligand-binding domain to the co-inhibitory proteins SMRT and NCoR. GW6471 has antitumor activity, inhibiting cell proliferation and inducing apoptosis.
价 格:¥电议型 号:T8486产 地:中国大陆
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T8471Vonafexor;化合物VonafexorEYP001|||PLX007|||pxl007;EYP001|||PLX007|||pxl007
Vonafexor (EYP001) is a farnesoid X receptor (FXR, NR1H4) agonist, with anti-HBV effects
价 格:¥电议型 号:T8471产 地:中国大陆
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T8347110-Deacetyl-13-oxobaccatin III;化合物 10-Deacetyl-13-oxobaccatin III10-Deacetyl-13-oxobaccatin III
10-Deacetyl-13-oxobaccatin III, a taxane isolated from Taxus sumatrana, exhibits cytotoxicity at a concentration of 30 μg/mL, inhibiting A498, NCI-H226, A549, and PC-3 cancer cell lines with respective rates of 29.7%, 49.2%, 43.9%, and 65.3% [1].
价 格:¥电议型 号:T83471产 地:中国大陆
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T82471Encelimab;化合物 EncelimabEncelimab
Encelimab, an anti-LAG3 antibody, inhibits the LAG-3/MHC II interaction to promote T-cell activation and, when used alone or alongside an anti-PD-1 antibody, shrinks tumors in a lymphoma mouse model (A20 cell xenograft) [1].
价 格:¥电议型 号:T82471产 地:中国大陆
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T81471Phytoene desaturase-IN-2;化合物 Phytoene desaturase-IN-2Phytoene desaturase-IN-2
"PDS-IN-1 potently inhibits Oryza sativa phytoene desaturase (OsPDS), exhibiting herbicidal activity [1]."
价 格:¥电议型 号:T81471产 地:中国大陆
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T80471α-Conotoxin MrIC;化合物 α-Conotoxin MrICα-Conotoxin MrIC
α-Conotoxin MrIC is a biased agonist selective for the α7 nicotinic acetylcholine receptor (nAChR), with activation contingent upon the presence of type II positive allosteric modulators, such as PNU120596. It is utilized to investigate neurological disorders and delineate the pharmacological characteristics of the α7nAChR [1].
价 格:¥电议型 号:T80471产 地:中国大陆
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T79471Antileishmanial agent-20;化合物 Antileishmanial agent-20Antileishmanial agent-20
Antileishmanial agent-20 exhibits selectivity against the Leishmania parasite, with IC50 values of 2.8 μM for L. infantum and 0.2 μM for L. braziliensis. It is a potential research tool for studying these parasites [1].
价 格:¥电议型 号:T79471产 地:中国大陆
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T78471α,α-Trehalose 6-phosphate potassium;海藻糖6-磷酸二钾盐Tre6P potassium;Tre6P potassium
α,α-Trehalose 6-phosphate (Tre6P) potassium is an intrinsic 6-phosphate derivative of α,α′-trehalose and acts as an intermediary metabolite. It undergoes enzymatic conversion to the final metabolic product, α,α′-trehalose, via the enzyme Tre6P phosphatase (T6PP) [1].
价 格:¥电议型 号:T78471产 地:中国大陆
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T77471Tinurilimab;替奴瑞利单抗BAY 1834942;BAY 1834942
Tinurilimab (Bay 1834942) is a monoclonal antibody that targets and inhibits CEACAM6, an immune checkpoint regulator. Tinurilimab can be used in studies about effector T-cells against tumors.
价 格:¥电议型 号:T77471产 地:中国大陆
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T76734CTX-471;化合物 CTX-471CTX-471
CTX-471, a fully human monoclonal antibody targeting CD137, exhibits binding affinity for CD137 across multiple species, including humans, cynomolgus macaques, and mice, with dissociation constant (Kd) values of 50 nM, 61 nM, and 748 nM, respectively. This compound is utilized in the study of immunomodulation and cancer research [1].
价 格:¥电议型 号:T76734产 地:中国大陆