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T75859FTSDVSKQMEEEAVRLFIEWLKNGGPSSGAPPPS;化合物 FTSDVSKQMEEEAVRLFIEWLKNGGPSSGAPPPSFTSDVSKQMEEEAVRLFIEWLKNGGPS
FTSDVSKQMEEEAVRLFIEWLKNGGPSSGAPPPS is an Exendin-4 peptide derivative.
价 格:¥电议型 号:T75859产 地:中国大陆
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T75858LL-37, human acetate;化合物 LL-37, human acetateLL-37, human acetate
LL-37, human acetate, is a 37-residue amphipathic peptide derived from cathelicidin, known for its broad-spectrum antimicrobial properties. This compound not only plays a crucial role in safeguarding the cornea against infection but also modulates wound healing [1] [2] [3].
价 格:¥电议型 号:T75858产 地:中国大陆
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T75857LL-37, human TFA;化合物 LL-37, human TFALL-37, human TFA
LL-37, human TFA, is a cathelicidin-derived, 37-residue, amphipathic antimicrobial peptide that displays a broad spectrum of antimicrobial activity. It may protect the cornea from infection and modulate wound healing [1] [2] [3].
价 格:¥电议型 号:T75857产 地:中国大陆
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T75856Huwentoxin-IV TFA;化合物 Huwentoxin-IV TFAHuwentoxin-IV TFA
Huwentoxin-IV TFA is a potent, selective blocker of sodium channels, specifically inhibiting neuronal Nav1.7, Nav1.2, Nav1.3, and Nav1.4 with IC50 values of 26, 150, 338, and 400 nM, respectively. It preferentially targets the peripheral nerve subtype Nav1.7 by interacting with neurotoxin receptor site 4, demonstrating analgesic effects in animal models of inflammatory and neuropathic pain [1] [2].
价 格:¥电议型 号:T75856产 地:中国大陆
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T75855Phrixotoxin 3 TFA;化合物 Phrixotoxin 3 TFAPhrixotoxin 3 TFA
Phrixotoxin 3 TFA is a potent inhibitor of voltage-gated sodium channels, demonstrating IC50 values of 0.6 nM for NaV1.2, 42 nM for NaV1.3, 72 nM for NaV1.4, 288 nM for NaV1.1, and 610 nM for NaV1.5, respectively. This compound modulates the activity of these channels similarly to traditional gating-modifier toxins, inducing a depolarizing shift in gating kinetics as well as obstructing the inward sodium current.
价 格:¥电议型 号:T75855产 地:中国大陆
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T75854[D-Trp8]-γ-MSH TFA;化合物 [D-Trp8]-γ-MSH TFA[D-Trp8]-γ-MSH TFA
[D-Trp8]-γ-MSH TFA is a potent, selective agonist for the melanocortin 3 (MC3) receptor, demonstrating IC50 values of 6.7 nM for hMC3, 600 nM for hMC4, and 340 nM for hMC5 in CHO cells, respectively. It shows potential in providing protection against various inflammatory disorders, including rheumatoid arthritis and colitis [1] [2].
价 格:¥电议型 号:T75854产 地:中国大陆
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T75853HS014 TFA;化合物 HS014 TFAHS014 TFA
HS014 TFA, a potent and selective antagonist of the melanocortin-4 (MC4) receptor, exhibits K i values of 3.16, 108, 54.4, and 694 nM for the human MC4, MC1, MC3, and MC5 receptors, respectively. It effectively increases food intake in free-feeding rats [1] [2].
价 格:¥电议型 号:T75853产 地:中国大陆
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T75852HS024 TFA;化合物 HS024 TFAHS024 TFA
HS024, a selective MC4 receptor antagonist, exhibits affinity with Ki values of 0.29, 3.29, 5.45, and 18.6 nM for MC4, MC5, MC3, and MC1 receptors, respectively. This compound has been shown to increase food intake [1].
价 格:¥电议型 号:T75852产 地:中国大陆
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T75851γ1-MSH TFA;化合物 γ1-MSH TFAγ1-MSH TFA
γ1-MSH TFA, a melanocortin MC3 receptor agonist, demonstrates a binding affinity (K i) of 34 nM for the rat MC3 receptor. Notably, it exhibits approximately 40-fold greater selectivity for the MC3 receptor compared to the MC4 receptor, with a K i of 1318 nM for MC4 [1].
价 格:¥电议型 号:T75851产 地:中国大陆
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T75850JKC363 TFA;化合物 JKC363 TFAJKC363 TFA
JKC363 TFA is a selective melanocortin MC4 receptor antagonist that exhibits a 90-fold higher affinity for the MC4 receptor (IC50=0.5 nM) compared to the MC3 receptor (44.9 nM). This compound effectively inhibits the α-MSH-induced stimulation of TRH release. It also demonstrates an anti-hyperalgesic effect [1] [2].
价 格:¥电议型 号:T75850产 地:中国大陆
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T75585Naja Mossambica Venom;化合物 Naja Mossambica VenomNaja Mossambica Venom
Naja Mossambica Venom (Mozambique Spitting Cobra Venom) is a snake venom derived from Naja Mossambica, exhibiting antifungal activity against Candida species. Additionally, extracts from Naja Mossambica Venom, including phospholipase A2, can inhibit the activity of sodium-potassium ATPases [1] [2].
价 格:¥电议型 号:T75585产 地:中国大陆
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T745855-Methylcytidine 5′-triphosphate trisodium;化合物 5-Methylcytidine 5′-triphosphate trisodium5-Methylcyt
5-Methylcytidine 5′-triphosphate trisodium (5-Methyl-CTP trisodium), a modified nucleoside triphosphate, enhances translational properties and stability, while reducing innate immune responses in human and mammalian cells when used to replace unmodified mRNA [1].
价 格:¥电议型 号:T74585产 地:中国大陆
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T74141ARD-2585;化合物 ARD-2585ARD-2585
ARD-2585 is a highly potent and orally bioavailable proteolysis-targeting chimera (PROTAC) that effectively degrades the androgen receptor [1].
价 格:¥电议型 号:T74141产 地:中国大陆
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T73585PU.1-IN-1;化合物PU.1-IN-1PU.1-IN-1
PU.1-IN-1 is a potent PU.1 inhibitor (IC50 : 2 nM) with anti-inflammatory activity.
价 格:¥电议型 号:T73585产 地:中国大陆
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T71585DB03417;化合物 DB03417DB03417
DB03417 is a compound listed in web page: https://go.drugbank.com/drugs/DB03417. DB03417 is a potential tryptase inhibitor.
价 格:¥电议型 号:T71585产 地:中国大陆
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T70585Cyclazosin HCl;化合物 Cyclazosin HClCyclazosin HCl
Cyclazosin HCl is a hydrochloride composed of equimolar amounts of cyclazosin and hydrogen chloride. It has a role as an alpha1B-adrenoceptor antagonist. It contains a cyclazosin.
价 格:¥电议型 号:T70585产 地:中国大陆
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T69915GX-585;化合物 GX-585GX-585
GX-585 is a novel potent inhibitor of NaV1.7 and highly selective against NaV1.5, having limited selectivity against NaV1.1 and NaV1.2.
价 格:¥电议型 号:T69915产 地:中国大陆
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T69585GMC-1111 free base;化合物 GMC-1111 free baseGMC-1111 free base
GMC-1111 free base is a dopamine partial agonist and stabilizer.
价 格:¥电议型 号:T69585产 地:中国大陆
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T69336NNC-11-1585;化合物 NNC-11-1585NNC-11-1585
NNC-11-1585 is an M(1) and M(2) muscarinic acetylcholine receptor (mAChR) agonist.
价 格:¥电议型 号:T69336产 地:中国大陆
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T68585Piroximone;化合物 PiroximonePiroximone
Piroximone is a phosphodiesterase (PDE) inhibitor.
价 格:¥电议型 号:T68585产 地:中国大陆