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T62420P2Y2R/GPR17 antagonist 1
P2Y2R/GPR17 antagonist 1 (Compound 14m) is a dual P2Y2R and GPR17 antagonist. P2Y2R/GPR17 antagonist 1 shows IC50 values of 3.17 ?M and 1.67 ?M against P2Y2R and GPR17, respectively. P2Y2R/GPR17 antagonist 1 shows excellent metabolic stability in human liver microsomes.
价 格：￥电议型 号：T62420产 地：中国大陆
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T6462DeltarasinDeltarasin,Phosphodiesterase (PDE),inhibit,Inhibitor,Ras
Deltarasin is a small molecular inhibitor of KRAS-PDEδ interaction with Kd of 38 nM for binding to purified PDEδ.
价 格：￥电议型 号：T6462产 地：中国大陆
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T7165Basmisanilα subunit-containing GABAA receptors (GABAAα5),RO-5186582,RG-1662,psychiatric disorders,ne
Basmisanil is a negative allosteric modulator/inverse agonist of GABAAα5 receptors.Formulations containing basmisanil are in clinical trials for the treatment of cognitive impairments associated with Down syndrome.
价 格：￥电议型 号：T7165产 地：中国大陆
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TP1459LGly-Arg-Gly-Asp-Ser acetate(96426-21-0 free base)GlyArgGlyAspSer acetate(96426210 free base),Gly Arg
Gly-Arg-Gly-Asp-Ser (GRGDS) acetate is a cell binding protein domain derived from the cell-binding region of fibronectin.
价 格：￥电议型 号：TP1459L产 地：中国大陆
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T10762Ceranib1Ceranib-1,Ceranib1
Ceranib1 is an inhibitor of ceramidase. It inhibits the proliferation of ovarian cancer cells. Ceranib1 inhibits ceramidase activity toward an exogenous ceramide analog, induces the accumulation of multiple ceramide species, decreases levels of S1P and sphingosine.
价 格：￥电议型 号：T10762产 地：中国大陆
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TN1620Eriocalyxin BEriocalyxin B,inhibit,Apoptosis,Inhibitor
Eriocalyxin B induces apoptosis and cell cycle arrest in pancreatic adenocarcinoma cells through caspase- and p53-dependent pathways, should be considered a candidate for pancreatic cancer treatment; it is a specific inhibitor of STAT3, it directly targets STAT3 through a covalent linkage to inhibit the phosphorylation and activation of STAT3 and induces apoptosis of STAT3-dependent tumor cells.
价 格：￥电议型 号：TN1620产 地：中国大陆
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T8970ML162p62,Glutathione Peroxidase,GPX4,ML-162,Nrf2,anticancer,HRAS,Ferroptosis,Inhibitor,inhibit,ML 16
ML162 is an inhibitor of GPX4 that is selectively lethal to mutant RAS oncogene-expressing cell lines (IC50s = 25 and 578 nM for HRASG12V-expressing and wild-type BJ fibroblasts, respectively)
价 格：￥电议型 号：T8970产 地：中国大陆
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T6843GDC-0623Mitogen-activated protein kinase kinase,Apoptosis,inhibit,MEK,Inhibitor,MAP2K,MAPKK,MEK inhi
GDC-0623 is a potent and ATP-uncompetitive MEK1 inhibitor with Ki of 0.13 nM. Phase 1.
价 格：￥电议型 号：T6843产 地：中国大陆
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T91118-Azaadenosinethyroid,inhibit,editing,LIN28B,invasion,proliferation,Cal62,migration,8Azaadenosine,RN
8-Azaadenosine is a potent ADAR1 inhibitor and an A-to-I editing inhibitor. It blocks RNA editing and inhibits proliferation, 3D growth, invasion, and migration in thyroid cancer cells.
价 格：￥电议型 号：T9111产 地：中国大陆
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T12629LMIK665
MIK665 (S-64315) has an inhibitory effect on myeloid leukemia.
价 格：￥电议型 号：T12629L产 地：中国大陆
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T76216-?ThioinosineNucleoside Antimetabolite/Analog,6 ?Thioinosine,6-?Thioinosine,inhibit,Inhibitor,6?Thi
6- Thioinosine (6TI) is a purine antimetabolite, acts as an anti-adipogenesis agent.
价 格：￥电议型 号：T7621产 地：中国大陆
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T6620Ospemifeneinhibit,Ospemifene,Inhibitor,Estrogen Receptor/ERR
Ospemifene is a new selective non-hormonal estrogen receptor modulator (SERM) that is used for the treatment of moderate to severe dyspareunia, a symptom of vulvar and vaginal atrophy, due to menopause. FDA approved on February 26, 2013.
价 格：￥电议型 号：T6620产 地：中国大陆
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T7629OlesoximeInhibitor,NSC21311,NSC-21311,TRO19622,Olesoxime,inhibit,TRO-19622,Mitochondrial Metabolism
Olesoxime (TRO19622), A Mitochondrial-Targeted Neuroprotective Compound,is an experimental neuroprotective drug.
价 格：￥电议型 号：T7629产 地：中国大陆
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TP1627LPrepro VIP (111-122), human acetatePrepro VIP (111122), human acetate,Prepro VIP (111 122), human ac
Prepro VIP (111-122), human acetate is a prepro-vasoactive intestinal polypeptide (VIP)–derived peptide, corresponding to residues 111-122.
价 格：￥电议型 号：TP1627L产 地：中国大陆
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T6626PF-3758309proliferation,tumor,PF-3758309,oncogenic,survival,PF03758309,PF3758309,inhibit,p21 activat
PF-03758309 (IC50=1.3 nM), a pyrrolopyrazole inhibitor of PAK4, has effective ATP-competition.
价 格：￥电议型 号：T6626产 地：中国大陆
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T9572BMS986299
BMS986299 is a modulator of NLRP3 with an EC50 of 1.28 μM and can be used in studies about NLRP3 signaling and the treatment of associated diseases.
价 格：￥电议型 号：T9572产 地：中国大陆
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T7362O-304O 304,AMPK,O-304,inhibit,Inhibitor,AMP-activated protein kinase,O304
O-304 is a pan-activator of AMP-activated protein kinase (AMPK).
价 格：￥电议型 号：T7362产 地：中国大陆
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T7609ARS-1620inhibit,Ras,Inhibitor,ARS-1620,ARS 1620,ARS1620
ARS-1620 is a covalent inhibitor of K-RASG12C.
价 格：￥电议型 号：T7609产 地：中国大陆
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T6641Rilmenidine Phosphatecells,inhibit,Imidazoline Receptor,Beta Receptor,Rilmenidine Phosphate,K562,pro
Rilmenidine Phosphate is a selective I(1) imidazoline receptor agonist, used to treat hypertension.
价 格：￥电议型 号：T6641产 地：中国大陆
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T7624DAPTAHIV,DAPTA,CC chemokine receptor,Human immunodeficiency virus,inhibit,CCR,Inhibitor
DAPTA(TFA) is an inhibitor of CCR5, shows potent anti-HIV activities.
价 格：￥电议型 号：T7624产 地：中国大陆
