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  • T77621Z16078526化合物Z16078526Z 16078526|||Z16078526|||Z16078526

    Z16078526 enhances thermogenesis in mice by inducing endogenous Ucp1 expression, promoting p38 MAPK phosphorylation, and stimulating lipolysis in primary mouse brown adipocytes. Additionally, it activates thermogenic gene expression and mitochondrial activity, specifically uncoupled respiration, in these cells.

    价 格:¥电议型 号:T77621产 地:中国大陆

  • T76621Suc-Ala-Ala-Pro-Phe-SBzl;化合物 Suc-Ala-Ala-Pro-Phe-SBzlSuc-Ala-Ala-Pro-Phe-SBzl

    Suc-Ala-Ala-Pro-Phe-SBzl serves as a substrate for rat intestinal mast cell protease (RMCP I), rat skeletal muscle mast cell protease (RMCP II), and Chymotrypsin. Additionally, it undergoes hydrolysis by glycine (R208G) [1] [2].

    价 格:¥电议型 号:T76621产 地:中国大陆

  • T76219LMDP1 acetate;化合物 MDP1 acetateMDP1 acetate

    MDP1 acetate, a derivative of Melittin, compromises the membrane integrity of both Gram-positive and Gram-negative bacteria leading to bacterial death through membrane damage. It exhibits potent antibacterial activity against multidrug-resistant (MDR) and reference strains of S. aureus, E. coli, and P. aeruginosa [1].

    价 格:¥电议型 号:T76219L产 地:中国大陆

  • T76219MDP1;化合物 MDP1MDP1

    MDP1, derived from Melittin, disrupts the membrane integrity of both Gram-positive and Gram-negative bacteria, leading to bacterial death through membrane damage. This compound exhibits potent antibacterial activity against multidrug-resistant (MDR) and reference strains of S. aureus, E. coli, and P. aeruginosa [1].

    价 格:¥电议型 号:T76219产 地:中国大陆

  • T76218Targeting the bacterial sliding clamp peptide 46;化合物 Targeting the bacterial sliding clamp peptide 4

    Peptide 46 is a short peptide that inhibits SC-dependent DNA synthesis by targeting the bacterial sliding clamp (SC).

    价 格:¥电议型 号:T76218产 地:中国大陆

  • T76217Ac-Val-Gln-aIle-Val-aTyr-Lys-NH2;化合物 Ac-Val-Gln-aIle-Val-aTyr-Lys-NH2Ac-Val-Gln-aIle-Val-aTyr-Lys-NH

    Ac-Val-Gln-aIle-Val-aTyr-Lys-NH2 demonstrates serum stability and non-toxicity to neuronal cells, while selectively inhibiting the fibrilization of tau in preference to Aβ 42.

    价 格:¥电议型 号:T76217产 地:中国大陆

  • T76216Lonodelestat TFA;化合物 Lonodelestat TFALonodelestat TFA

    Lonodelestat TFA (POL6014 TFA) is a potent, selective peptide inhibitor of human neutrophil elastase (hNE), demonstrating oral activity. It holds promise for cystic fibrosis (CF) research [1] [2] [3].

    价 格:¥电议型 号:T76216产 地:中国大陆

  • T76215LKRpep-2d TFA;化合物 KRpep-2d TFAKRpep-2d TFA

    KRpep-2d (TFA) is a potent inhibitor of K-Ras, effectively hindering the proliferation of K-Ras-driven cancer cells, thereby serving as a valuable asset for cancer research [1].

    价 格:¥电议型 号:T76215L产 地:中国大陆

  • T76215KRpep-2d;化合物 KRpep-2dKRpep-2d

    KRpep-2d, a potent inhibitor of K-Ras, effectively suppresses the proliferation of cancer cells driven by K-Ras. This compound is suitable for use in cancer research [1].

    价 格:¥电议型 号:T76215产 地:中国大陆

  • T762145′-Nucleotidase;化合物 5′-Nucleotidase5′-Nucleotidase

    5′-Nucleotidase (CD73), an ectoenzyme and intrinsic membrane glycoprotein, catalyzes the hydrolysis of 5-nucleotides into their corresponding nucleosides [1].

    价 格:¥电议型 号:T76214产 地:中国大陆

  • T76213HXR9 hydrochloride;化合物 HXR9 hydrochlorideHXR9 hydrochloride

    HXR9 hydrochloride, a cell-permeable peptide and competitive antagonist of the HOX/PBX interaction, selectively reduces cell proliferation and induces apoptosis in cells with elevated HOXA/PBX3 gene expression, notably MLL-rearranged leukemic cells [1] [2] [3]. By inhibiting the interaction between HOX proteins and the transcription factor PBX, which associates with HOX proteins in paralogue groups 1 to 8, it disrupts a critical regulatory mechanism in these cells.

    价 格:¥电议型 号:T76213产 地:中国大陆

  • T76212B 9430;化合物 B 9430B 9430

    B 9430 is a potent bradykinin B1/B2 receptor antagonist [1] .

    价 格:¥电议型 号:T76212产 地:中国大陆

  • T76211[Asp5]-Oxytocin acetate;化合物 [Asp5]-Oxytocin acetate[Asp5]-Oxytocin acetate

    [Asp5]-Oxytocin acetate is a neurohypophyseal hormone analogue positioned at the 5-position, noted for its significant biological activity. It stimulates uterine contractions in vitro, an effect that is amplified by the presence of Mg 2+. Furthermore, this compound exhibits rat uteroconstrictor, avian vasodilator, and rat antidiuretic capabilities.

    价 格:¥电议型 号:T76211产 地:中国大陆

  • T76210POT-4 TFA;化合物 POT-4 TFAPOT-4 TFA

    POT-4 TFA (AL-78898A TFA), a derivative of Compstatin, effectively inhibits the activation of complement factor C3. This compound is utilized in research related to age-related macular degeneration [1] [2].

    价 格:¥电议型 号:T76210产 地:中国大陆

  • T76216-?Thioinosine;6-疏基嘌呤核苷6-Mercaptopurine riboside|||6TI;6-Mercaptopurine riboside|||6-疏基嘌呤核苷|||6TI

    6-?Thioinosine (6TI) is a purine antimetabolite, acts as an anti-adipogenesis agent.

    价 格:¥电议型 号:T7621产 地:中国大陆

  • T75621Secalonic acid D;化合物 Secalonic acid DSecalonic acid D

    Secalonic acid D, a toxic compound effective against tumor cells, is derived from the metabolites of Aspergillus aculeatus. It operates by activating GSK3-β and degrading β-catenin, consequently down-regulating c-Myc expression, arresting the cell cycle at the G1 phase, and inducing cell apoptosis [1] [2].

    价 格:¥电议型 号:T75621产 地:中国大陆

  • T74621STING agonist-9;化合物 STING agonist-9STING agonist-9

    STING Agonist-9 (Compound 45) is a powerful stimulator of the STING pathway, demonstrating potent activity with an EC50 of 1.2 nM against human STING (h-STING) and 32.82 μM against mouse STING (m-STING). It exhibits antitumor activity [1].

    价 格:¥电议型 号:T74621产 地:中国大陆

  • T73698Basiliximab;巴利昔单抗CHI 621;CHI 621

    Basiliximab (CHI 621) is a chimeric mouse/human IgG1 monoclonal recombinant antibody against the interleukin-2 receptor. Basiliximab has good immunosuppressive activity and can be used in the study of kidney transplantation.

    价 格:¥电议型 号:T73698产 地:中国大陆

  • T72819UNC6212 (Kme2);化合物 UNC6212 (Kme2)UNC6212 (Kme2)

    UNC6212 (Kme2), a dimethyllysine (Kme2)-containing ligand, has a K D for CBX5 of 5.7 μM [1] .

    价 格:¥电议型 号:T72819产 地:中国大陆

  • T72621GCGR antagonist 2;化合物 GCGR antagonist 2GCGR antagonist 2

    GCGR Antagonist 2, a Furan-2-carbohydrazide, serves as an orally active antagonist of the glucagon receptor. It exhibits affinity for the human glucagon receptor (hGluR) with a dissociation constant (Kd) of 2.3 nM and demonstrates inhibitory activity against the rat receptor with a half-maximal inhibitory concentration (IC50) of 0.43 nM. Additionally, this compound effectively prevents glucagon-stimulated glycogenolysis.

    价 格:¥电议型 号:T72621产 地:中国大陆

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