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T16679PT2977PT2977,MK-6482,
PT2977 is a potential treatment for clear cell renal cell carcinoma (ccRCC). PT2977 is an orally active and selective HIF-2α inhibitor (IC50: 9 nM). PT2977, as a second-generation HIF-2α inhibitor, increases potency and improves pharmacokinetic profile.
价 格:¥电议型 号:T16679产 地:美洲
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T16759RitanserinRitanserin,R 55667,
Ritanserin is a highly effective, relatively selective, long-acting antagonist of 5-HT2 receptor (IC50: 0.9 nM).
价 格:¥电议型 号:T16759产 地:美洲
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T1984CinaciguatCinaciguat,BAY 58-2667,
Cinaciguat (BAY 58-2667) is the first of a new class of soluble guanylate cyclase (sGC) activators in clinical development for acute decompensated heart failure.
价 格:¥电议型 号:T1984产 地:美洲
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T2332ElvitegravirElvitegravir,D06677,JTK-303
Elvitegravir is a Human Immunodeficiency Virus Integrase Strand Transfer Inhibitor. The mechanism of action of elvitegravir is as an HIV Integrase Inhibitor, and Cytochrome P450 2C9 Inducer.
价 格:¥电议型 号:T2332产 地:美洲
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T2667PIK75PIK75
PIK-75, a DNA-PK and PI3K inhibitor, suppresses DNA-PK(IC50=2 nM), p110α(IC50=5.8 nM) and p110γ(IC50=76 nM).
价 格:¥电议型 号:T2667产 地:美洲
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T4538palovarotenepalovarotene,Ro 3300074,R 667
Palovarotene is an agonist of nuclear retinoic acid receptor γ (RAR-γ).
价 格:¥电议型 号:T4538产 地:美洲
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T5667Acetic acid octyl esterAcetic acid octyl ester
Acetic acid octyl ester is the acetate ester of octan-1-ol. It has a role as a plant metabolite.Acetic acid octyl ester is present in citrus peel oils.
价 格:¥电议型 号:T5667产 地:美洲
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T6261CP-466722CP-466722,CP466722,CP 466722
CP-466722, an effective and reversible ATM inhibitor, does not inhibit ATR and PI3K or PIKK family members in cells.
价 格:¥电议型 号:T6261产 地:美洲
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T8667MC-Gly-Gly-Phe-Gly;化合物DSN28369DSN28369;DSN28369
MC-Gly-Gly-Phe-Gly (DSN28369) is a heterobifunctional linker, and useful to make antibody drug conjuate (ADC).
价 格:¥电议型 号:T8667产 地:中国大陆
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T83667A11 TFA;化合物 A11 TFACPP-EYVQTVKSSKG;CPP-EYVQTVKSSKG
A11, a cell-penetrating peptide, integrates the HIV-1 Tat protein transduction domain with an 11-amino acid segment from the annexin A1 N-terminus (residues 20-30). This compound disrupts the interaction between annexin A1 and the Eph receptor tyrosine kinase A2 (EphA2), leading to enhanced EphA2 ubiquitination in HK1 nasopharyngeal carcinoma (NPC) cells. At a concentration of 10 ?M, A11 curtails proliferation, migration, and invasion of HK1 and 5-8F NPC cells. Furthermore, A11 demonstrably dimi
价 格:¥电议型 号:T83667产 地:中国大陆
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T82667CRT0063465;化合物 CRT0063465CRT0063465
CRT0063465 is a ligand for both human Phosphoglycerate Kinase 1 (PGK1) and the stress sensor protein DJ-1, exhibiting a dissociation constant (Kd) of 24 μM for PGK1. Additionally, it influences the composition of the shelterin complex and modulates telomere length [1].
价 格:¥电议型 号:T82667产 地:中国大陆
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T81667NLRP3 agonist 2;化合物 NLRP3 agonist 2NLRP3 agonist 2
NLRP3 agonist 2 (compound 22) is an orally active agent that activates Caspase-1 in THP1 cells [1].
价 格:¥电议型 号:T81667产 地:中国大陆
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T80733ZH8667;化合物 ZH8667ZH8667
ZH8667 is a TAAR1-Gs agonist that holds potential for schizophrenia research [1].
价 格:¥电议型 号:T80733产 地:中国大陆
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T806672-Methyl-1-Pyrroline;2-甲基吡咯啉2-Methyl-1-Pyrroline
2-Methyl-1-Pyrroline (2-MPN) is an intermediate of a photochemical dye that induces the formation of (R)-2-MP.
价 格:¥电议型 号:T80667产 地:中国大陆
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T79667YCH1899;化合物 YCH1899YCH1899
YCH1899, an orally active PARP inhibitor, demonstrates potent inhibition of PARP1/2 with an IC50 of less than 0.001 nM. It shows marked antiproliferative efficacy against Olaparib-resistant (Capan-1/OP) and Talazoparib-resistant (Capan-1/TP) cells with IC50 values of 0.89 nM and 1.13 nM, respectively. Moreover, YCH1899 possesses favorable pharmacokinetic attributes in rats [1].
价 格:¥电议型 号:T79667产 地:中国大陆
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T79500LKSK94 FA;KSK94 甲酸盐KSK94 FA(2566716-07-0 Free base);KSK94 FA(2566716-07-0 Free base)
KSK94 FA is a potent histamine H3 receptor antagonist that inhibits H3 receptors and is used in the study of neuropathic pain and obesity.
价 格:¥电议型 号:T79500L产 地:中国大陆
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T78667FAPI-74;化合物 FAPI-74FAPI-74
FAPI-74 serves as a positron emission tomography (PET) tracer specifically targeting fibroblast activation protein (FAP), utilized in the study of FAP-positive tumors [1].
价 格:¥电议型 号:T78667产 地:中国大陆
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T77807CHI-000-667;化合物 CHI-000-667CHI-000-667
CHI-000-667 can be used in studies about Ras.
价 格:¥电议型 号:T77807产 地:中国大陆
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T76679Etokimab;化合物 EtokimabEtokimab
Etokimab (Antibody ANB 020), a humanized monoclonal antibody, specifically targets IL-33. It is utilized in the research of atopic dermatitis [1].
价 格:¥电议型 号:T76679产 地:中国大陆
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T76678Eptinezumab;化合物 EptinezumabEptinezumab
Eptinezumab, a human monoclonal antibody, specifically binds to and blocks the calcitonin gene-related peptide (CGRP) from binding to its receptor, thus acting as a preventive treatment for migraine in adults [1].
价 格:¥电议型 号:T76678产 地:中国大陆