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  • T5784TopotecanTopotecan,SKF 104864A,NSC 609669

    Topotecan is a Topoisomerase I inhibitor,and is an antineoplastic agent used to treat ovarian cancer that works by inhibiting DNA topoisomerases.

    价 格：￥电议型 号：T5784产 地：美洲

  • T5S0669BergamotineBergamotine,Bergaptin,5-Geranoxypsoralen

    1. Bergamotine can significantly reduce blood glucose and increase glucose tolerance and insulin sensitivity in KK-Aydiabetic mice.

    价 格：￥电议型 号：T5S0669产 地：美洲

  • T83669PMX-53 TFA；化合物 PMX-53 TFAAcPhe-[Orn-Pro-D-Cyclohexylalanine-Trp-Arg]|||AcF-[OPdChaWR]|||3D53；AcPhe-[

    PMX-53, a macrocyclic complement 5a (C5a) peptidomimetic and C5a receptor antagonist (IC50 = 0.3 ?M), effectively inhibits the C5a-induced secretion of myeloperoxidase (MPO) in isolated human polymorphonuclear leukocytes (PMNs). Administered orally at 10 mg/kg, PMX-53 mitigates vascular leakage, PMN infiltration, and the production of TNF-α and IL-6 in a rat peritoneal Arthus reaction model. Additionally, in a 3-nitropropionic acid (3-NP)-induced Huntington’s disease rat model, it alleviates bod

    价 格：￥电议型 号：T83669产 地：中国大陆

  • T82669Crocetin dialdehyde；化合物 Crocetin dialdehydeCrocetin dialdehyde

    Crocetin dialdehyde, a natural product, is present in saffron [1].

    价 格：￥电议型 号：T82669产 地：中国大陆

  • T81669NKG2D-IN-2；化合物 NKG2D-IN-2NKG2D-IN-2

    NKG2D-IN-2 (compound 47) is an inhibitor of the natural killer group 2D receptor (NKG2D), demonstrating half-maximal inhibitory concentrations (IC50s) of 0.1 ?M for NKG2D/MICA and 0.2 ?M for ULBP6 in time-resolved fluorescence resonance energy transfer (TR-FRET) assays [1].

    价 格：￥电议型 号：T81669产 地：中国大陆

  • T79669FD2157；化合物 FD2157FD2157

    FD2157, a photosensitive PI3K inhibitor, exhibits inhibitory IC50 values of 43 nM for PI3Kα, 83 nM for PI3Kβ, 84 nM for PI3Kγ, and 14 nM for PI3Kδ. Upon exposure to 365 nm UV light, FD2157 effectively inhibits cancer cell proliferation and induces apoptosis [1].

    价 格：￥电议型 号：T79669产 地：中国大陆

  • T78756Yhhu6669；化合物 Yhhu6669Yhhu6669

    Yhhu6669 is an anti-HBV agent that suppresses viral DNA and replication by promoting DNA-free capsid assembly, effectively reducing HBV DNA and HBcAg levels in AAV/HBV-infected mice and demonstrating favorable pharmacokinetic (PK) properties [1].

    价 格：￥电议型 号：T78756产 地：中国大陆

  • T78669(1R,4S)-Yimitasvir diphosphate；化合物 (1R,4S)-Yimitasvir diphosphate(1R,4S)-DAG-181 diphosphate|||(1R,4

    Yimitasvir diphosphate, also known as Emitasvir, is an orally-administered inhibitor of the hepatitis C virus (HCV) nonstructural protein 5A (NS5A). It is utilized in the study of chronic hepatitis C virus infections [1].

    价 格：￥电议型 号：T78669产 地：中国大陆

  • T76699Sabatolimab；Sabatolimab单抗MBG453|||NVP-MBG453；MBG453|||NVP-MBG453

    Sabatolimab (MBG453), a humanized IgG4 (S228P) antibody targeting TIM-3, is a potent inhibitory receptor that regulates adaptive and innate immune responses. Sabatolimab has potential immunosuppressive activity and selectively binds to TIM-3 on immune cells and bone marrow cells.

    价 格：￥电议型 号：T76699产 地：中国大陆

  • T76698Rovalpituzumab；洛伐妥珠单抗Rovalpituzumab

    Rovalpituzumab is a humanized monoclonal antibody targeting delta-like protein 3 (DLL3). Rovalpituzumab can be used to synthesize antibody-active molecule conjugates (ADCs). Rovalpituzumab has anticancer activity and is used to treat small cell lung cancer (SCLC).

    价 格：￥电议型 号：T76698产 地：中国大陆

  • T76697Panitumumab (anti-EGFR)；化合物 Panitumumab (anti-EGFR)Panitumumab (anti-EGFR)

    Panitumumab, a fully human IgG2 anti-EGFR monoclonal antibody, exerts anti-tumor effects by inhibiting tumor cell proliferation, survival, and angiogenesis. It is utilized in researching various cancers, including colon cancer [1] [2] [4].

    价 格：￥电议型 号：T76697产 地：中国大陆

  • T76696Onvatilimab；奥瓦利单抗JNJ-61610588；JNJ-61610588

    Onvatilimab (JNJ-61610588) is a human IgG1 κ-anti-Vista (T-cell-activated V-domain Ig inhibitor) monoclonal antibody. Onvatilimab has antitumor activity and can be used to treat advanced head and neck cancers.

    价 格：￥电议型 号：T76696产 地：中国大陆

  • T76695Oleclumab；化合物 OleclumabOleclumab

    Oleclumab (MEDI9447), a human IgG1λ monoclonal antibody, targets and inhibits CD73 functionality, demonstrating anti-tumor activity [1].

    价 格：￥电议型 号：T76695产 地：中国大陆

  • T76694Odronextamab；化合物 OdronextamabOdronextamab

    Odronextamab, a fully human, hinge-stabilized IgG4-based bispecific antibody, targets CD3 receptors on T cells and CD20 receptors on B cells [1].

    价 格：￥电议型 号：T76694产 地：中国大陆

  • T76693Moxetumomab；化合物 MoxetumomabMoxetumomab

    Moxetumomab, a recombinant immunotoxin targeting CD22, is utilized in the study of hairy cell leukemia (HCL) [1] [2].

    价 格：￥电议型 号：T76693产 地：中国大陆

  • T76692Mosunetuzumab；莫妥珠单抗BTCT-4465A；BTCT-4465A

    Mosunetuzumab (BCT-4465A) is a humanized antibody based on immunoglobulin G1 that targets CD20 (B cells) and CD3 (T cells). Mosunetuzumab redirects T cells to engage and eliminate malignant B cells and can be used to study relapsed or refractory (R/R) B-cell non-Hodgkin lymphoma (B-NHL) and refractory follicular lymphoma.

    价 格：￥电议型 号：T76692产 地：中国大陆

  • T76691Monalizumab；莫那利珠单抗Monalizumab

    Monalizumab is a novel immune checkpoint inhibitor targeting natural killer cell population 2A (NKG2A). Monalizumab is a humanized monoclonal antibody against NKG2A that induces IFN-γ production, thereby activating natural killer cell function. Monalizumab has antitumor activity and can be used to study neck squamous cell carcinoma (HNSCC).

    价 格：￥电议型 号：T76691产 地：中国大陆

  • T76690Mavrilimumab；玛弗利木单抗CAM 3001；CAM 3001

    Mavrilimumab (CAM 3001) is a monoclonal antibody with antiviral activity that has an affinity for the α subunit of the granulocytic-macrophage colony-stimulating factor (GM-CSF) receptor and blocks downstream intracellular signaling of GM-CSF. GM-CSF may be associated with an overactive inflammatory response associated with respiratory failure and death, and could be used to study rheumatoid arthritis.

    价 格：￥电议型 号：T76690产 地：中国大陆

  • T7669RPW-24；化合物RPW-24RPW-24

    RPW-24 is a stimulator of host immune defenses, has antibacterial activity.

    价 格：￥电议型 号：T7669产 地：中国大陆

  • T76669Anti-MERS-D12 mAb；化合物 Anti-MERS-D12 mAbAnti-MERS-D12 mAb

    Anti-MERS-D12 mAb (MERS-D12; MERS Antibody-D12), a human monoclonal IgG1, specifically targets the DPP4 interacting region of the MERS-CoV Spike receptor binding domain (RBD). By directly binding to this region, it effectively neutralizes the virus by blocking its ability to bind to receptors [1].

    价 格：￥电议型 号：T76669产 地：中国大陆

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